NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology

Anti-Gag antibodies gag HIV infection and slow disease progression

(2018) Ali Ahmad et al.   AIDS

Interleukin-1β Stimulates BDNF Production in Eutopic Endometriosis Stromal Cell Cultures A Model for Cytokine Regulation of Neuroangiogenesis

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Targeting the NLRP3 inflammasome in inflammatory diseases

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Prediction of HIV-associated neurocognitive disorder (HAND) from three genetic features of envelope gp120 glycoprotein

(2018) Masato Ogishi et al.   Retrovirology

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Microglia and CNS Interleukin-1: Beyond Immunological Concepts

(2018) Xiaoyu Liu et al.   Frontiers in Neurology

The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo

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Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

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HIV-1 gp120 Upregulates Brain-Derived Neurotrophic Factor (BDNF) Expression in BV2 Cells via the Wnt/β-Catenin Signaling Pathway

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HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation

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Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research

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Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

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Mir-21 Mediates the Inhibitory Effect of Ang (1–7) on AngII-induced NLRP3 Inflammasome Activation by Targeting Spry1 in lung fibroblasts

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Group A streptococcal M protein activates the NLRP3 inflammasome

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Novel p75 neurotrophin receptor ligand stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV associated neuropathogenesis

(2016) Rick B. Meeker et al.   EXPERIMENTAL NEUROLOGY

Fate of microglia during HIV-1 infection: From activation to senescence?

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

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A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

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Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic Escherichia coli K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier

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Macrophage–sensory neuronal interaction in HIV-1 gp120-induced neurotoxicity

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Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

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Vimentin regulates activation of the NLRP3 inflammasome

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CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-Using HIV-1 Glycoprotein 120

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Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120-mediated brain inflammation

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The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

(2014) John G Walsh et al.   Retrovirology

Fingolimod phosphate promotes the neuroprotective effects of microglia

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HIV-associated neurocognitive disorder

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

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Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

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IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

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NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

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Involvement of Kv1.3 and p38 MAPK signaling in HIV-1 glycoprotein 120-induced microglia neurotoxicity

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HIV-1 gp120 enhances outward potassium current via CXCR4 and cAMP-dependent protein kinase a signaling in cultured rat microglia

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Association of Anti-Modified Citrullinated Vimentin with Subclinical Atherosclerosis in Early Rheumatoid Arthritis Compared with Anti-Cyclic Citrullinated Peptide

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M-tropic HIV envelope protein gp120 exhibits a different neuropathological profile than T-tropic gp120 in rat striatum

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Influenza virus activates inflammasomes via its intracellular M2 ion channel

(2010) Takeshi Ichinohe et al.   NATURE IMMUNOLOGY