Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research

IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury

(2017) Victoria E. Thaney et al.   Scientific Reports

Expression of gp120 in mice evokes anxiety behavior: Co-occurrence with increased dendritic spines and brain-derived neurotrophic factor in the amygdala

(2016) Alessia Bachis et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of HIV and Methamphetamine on Brain and Behavior: Evidence from Human Studies and Animal Models

(2016) Virawudh Soontornniyomkij et al.   Journal of Neuroimmune Pharmacology

Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity

(2016) Jerel A. Fields et al.   Journal of Neuroinflammation

HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders

(2016) Jerel Adam Fields et al.   NEUROBIOLOGY OF DISEASE

The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons

(2016) Valeria Avdoshina et al.   NEUROTOXICITY RESEARCH

Impaired neurogenesis by HIV-1-Gp120 is rescued by genetic deletion of fatty acid amide hydrolase enzyme

(2015) H K Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cognitive deficits associated with combined HIV gp120 expression and chronic methamphetamine exposure in mice

(2015) James P. Kesby et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Combination of methamphetamine and HIV-1 gp120 causes distinct long-term alterations of behavior, gene expression, and injury in the central nervous system

(2015) Melanie M. Hoefer et al.   EXPERIMENTAL NEUROLOGY

Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model

(2015) Nobuki Nakanishi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

HIV-1 and interferons: who's interfering with whom?

(2015) Tomas Doyle et al.   NATURE REVIEWS MICROBIOLOGY

Methamphetamine Exposure Combined with HIV-1 Disease or gp120 Expression: Comparison of Learning and Executive Functions in Humans and Mice

(2015) James P Kesby et al.   NEUROPSYCHOPHARMACOLOGY

Cerebrospinal Fluid HIV Escape from Antiretroviral Therapy

(2015) Francesca Ferretti et al.   Current HIV/AIDS Reports

Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders

(2014) Wolf Wrasidlo et al.   BRITISH JOURNAL OF PHARMACOLOGY

CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-Using HIV-1 Glycoprotein 120

(2014) Ricky Maung et al.   JOURNAL OF IMMUNOLOGY

Role of Neurotrophic Factor Alterations in the Neurodegenerative Process in HIV Associated Neurocognitive Disorders

(2014) Jerel Fields et al.   Journal of Neuroimmune Pharmacology

Activation of TRPML1 Clears Intraneuronal A  in Preclinical Models of HIV Infection

(2014) M. Bae et al.   JOURNAL OF NEUROSCIENCE

Interaction of Paroxetine with Mitochondrial Proteins Mediates Neuroprotection

(2014) Joseph P. Steiner et al.   Neurotherapeutics

Is the central nervous system a reservoir of HIV-1?

(2014) Lachlan R. Gray et al.   Current Opinion in HIV and AIDS

Prepulse inhibition in HIV-1 gp120 transgenic mice after withdrawal from chronic methamphetamine

(2013) Brook L. Henry et al.   BEHAVIOURAL PHARMACOLOGY

The cannabinoid CB2receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis

(2013) Hava Karsenty Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Prepulse Inhibition in HIV-Associated Neurocognitive Disorders

(2013) Arpi Minassian et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Where does HIV hide? A focus on the central nervous system

(2013) Melissa Churchill et al.   Current Opinion in HIV and AIDS

Expression of HIV gp120 protein increases sensitivity to the rewarding properties of methamphetamine in mice

(2012) James P. Kesby et al.   ADDICTION BIOLOGY

Behavioral effects of chronic methamphetamine treatment in HIV-1 gp120 transgenic mice

(2012) Brook L. Henry et al.   BEHAVIOURAL BRAIN RESEARCH

Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in synaptosomes of HIV/gp120 transgenic mice: Implications for HIV-associated neurodegeneration

(2012) Sugato Banerjee et al.   EXPERIMENTAL NEUROLOGY

Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

(2011) Christina Patrick et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis

(2011) Dejiang Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-1 Tat-Mediated Neurotoxicity in Retinal Cells

(2011) Nivedita Chatterjee et al.   Journal of Neuroimmune Pharmacology

A Failure to Normalize Biochemical and Metabolic Insults During Morphine Withdrawal Disrupts Synaptic Repair in Mice Transgenic for HIV-gp120

(2011) Veera Venkata Ratnam Bandaru et al.   Journal of Neuroimmune Pharmacology

Loss of Neuronal Integrity during Progressive HIV-1 Infection of Humanized Mice

(2011) P. K. Dash et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

(2011) Leslie Crews et al.   Molecular Neurodegeneration

Interactive Comorbidity between Opioid Drug Abuse and HIV-1 Tat

(2010) Sylvia Fitting et al.   AMERICAN JOURNAL OF PATHOLOGY

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders

(2010) Yeon-Joo Kang et al.   ANNALS OF NEUROLOGY

HIV-Associated Neurocognitive Disorder: Pathogenesis and Therapeutic Opportunities

(2010) Kathryn A. Lindl et al.   Journal of Neuroimmune Pharmacology

Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease

(2010) Myoung-Hwa Lee et al.   NEUROBIOLOGY OF DISEASE

A Reverse-Translational Study of Dysfunctional Exploration in Psychiatric Disorders

(2009) William Perry et al.   ARCHIVES OF GENERAL PSYCHIATRY

Interferon-  Causes Neuronal Dysfunction in Encephalitis

(2009) A. R. Sas et al.   JOURNAL OF NEUROSCIENCE

Alteration of Methamphetamine-induced stereotypic behaviour in transgenic mice expressing HIV-1 envelope protein gp120

(2009) Amanda J. Roberts et al.   JOURNAL OF NEUROSCIENCE METHODS

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

(2009) Brandon F. Keele et al.   NATURE

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

(2009) Shu-ichi Okamoto et al.   NATURE MEDICINE

The utilization of humanized mouse models for the study of human retroviral infections

(2009) Rachel Van Duyne et al.   Retrovirology

Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 tat transgenic mice

(2008) Annadora J. Bruce-Keller et al.   GLIA

HIV-1 Tat and morphine have interactive effects on oligodendrocyte survival and morphology

(2008) Kurt F. Hauser et al.   GLIA

Neurodegeneration and Ageing in the HAART Era

(2008) Bruce J. Brew et al.   Journal of Neuroimmune Pharmacology

HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis

(2007) Marcus Kaul   Frontiers in Bioscience-Landmark