Mir-21 Mediates the Inhibitory Effect of Ang (1–7) on AngII-induced NLRP3 Inflammasome Activation by Targeting Spry1 in lung fibroblasts

Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation

(2016) Heather W. Stout-Delgado et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease

(2016) Seonmin Lee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Celastrol-Induced Suppression of the MiR-21/ERK Signalling Pathway Attenuates Cardiac Fibrosis and Dysfunction

(2016) Mian Cheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Inhibiting miR-21 attenuates experimental hepatic fibrosis by suppressing both the ERK1 pathway in HSC and hepatocyte EMT

(2016) K. Wu et al.   CLINICAL SCIENCE

NLRP3 inflammasome expression in idiopathic pulmonary fibrosis and rheumatoid lung

(2016) Ismini Lasithiotaki et al.   EUROPEAN RESPIRATORY JOURNAL

Fibroproliferative effect of microRNA-21 in hypertrophic scar derived fibroblasts

(2016) Guangzao Li et al.   EXPERIMENTAL CELL RESEARCH

Inhibition of MicroRNA-21 induces apoptosis in dermal fibroblasts of patients with systemic sclerosis

(2016) Saeideh Jafarinejad-Farsangi et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

(2016) Isis Ludwig-Portugall et al.   KIDNEY INTERNATIONAL

MicroRNA-21 is associated with fibrosis in a rat model of nonalcoholic steatohepatitis and serves as a plasma biomarker for fibrotic liver disease

(2016) Ayano Takeuchi-Yorimoto et al.   TOXICOLOGY LETTERS

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular Activation of the NLRP3 Inflammasome in Fibrosis: Common Threads Linking Divergent Fibrogenic Diseases

(2015) Carol M. Artlett et al.   ANTIOXIDANTS & REDOX SIGNALING

The Angiotensin-Converting Enzyme 2/Angiotensin (1–7)/Mas Axis Protects Against Lung Fibroblast Migration and Lung Fibrosis by Inhibiting the NOX4-Derived ROS-Mediated RhoA/Rho Kinase Pathway

(2015) Ying Meng et al.   ANTIOXIDANTS & REDOX SIGNALING

Angiotensin-Converting Enzyme 2 Attenuates Bleomycin-Induced Lung Fibrosis in Mice

(2015) Lifang Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Microrna-21: A Central Regulator of Fibrotic Diseases Via Various Targets

(2015) Ying Huang et al.   CURRENT PHARMACEUTICAL DESIGN

Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis

(2015) Johan M. Lorenzen et al.   EUROPEAN HEART JOURNAL

Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells

(2015) Xiujuan Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Vector-mediated microRNA-21 silencing ameliorates granulomatous liver fibrosis inSchistosoma japonicuminfection

(2015) Martina Sombetzki et al.   HEPATOLOGY

Tanshinone IIA Attenuates Bleomycin-Induced Pulmonary Fibrosis via Modulating Angiotensin-Converting Enzyme 2/ Angiotensin-(1-7) Axis in Rats

(2014) Huajie Wu et al.   International Journal of Medical Sciences

Anti–microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways

(2014) Ivan G. Gomez et al.   JOURNAL OF CLINICAL INVESTIGATION

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

(2014) Alexander Wree et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Axis Protects against Lung Fibrosis by Inhibiting the MAPK/NF-κB Pathway

(2013) Ying Meng et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Angiotensin II type 1 and 2 receptors and lymphatic vessels modulate lung remodeling and fibrosis in systemic sclerosis and idiopathic pulmonary fibrosis

(2013) ER Parra et al.   Clinics

Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling

(2013) María José Acuña et al.   HUMAN MOLECULAR GENETICS

The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells

(2013) Mitsuhiro Yamada et al.   RESPIRATORY RESEARCH

Role of miR-21 in the pathogenesis of atrial fibrosis

(2012) Oliver Adam et al.   BASIC RESEARCH IN CARDIOLOGY

Angiotensin-(1–7): beyond the cardio-renal actions

(2012) Danielle G. Passos-Silva et al.   CLINICAL SCIENCE

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammasomes in liver diseases

(2012) Gyongyi Szabo et al.   JOURNAL OF HEPATOLOGY

MicroRNA-21: a ubiquitously expressed pro-survival factor in cancer and other diseases

(2011) Si Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension

(2010) Vinayak Shenoy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammation and Fibrosis during Chlamydia pneumoniae Infection Is Regulated by IL-1 and the NLRP3/ASC Inflammasome

(2010) X. He et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE