Group A streptococcal M protein activates the NLRP3 inflammasome

Human Monocytes Engage an Alternative Inflammasome Pathway

(2016) Moritz M. Gaidt et al.   IMMUNITY

Coiled-coil destabilizing residues in the group AStreptococcusM1 protein are required for functional interaction

(2016) Chelsea M. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein

(2016) Cosmo Z. Buffalo et al.   Nature Microbiology

The Inflammasomes and Autoinflammatory Syndromes

(2015) Lori Broderick et al.   Annual Review of Pathology-Mechanisms of Disease

Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing

(2015) Christopher N. LaRock et al.   Cell Host & Microbe

Vigilant Keratinocytes Trigger Pathogen-Associated Molecular Pattern Signaling in Response to Streptococcal M1 Protein

(2015) Sandra T. Persson et al.   INFECTION AND IMMUNITY

A molecular trigger for intercontinental epidemics of group A Streptococcus

(2015) Luchang Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Inflammasome/IL-1β Responses to Streptococcal Pathogens

(2015) Christopher N. LaRock et al.   Frontiers in Immunology

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

(2014) M. J. Walker et al.   CLINICAL MICROBIOLOGY REVIEWS

A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development

(2014) Martina Sanderson-Smith et al.   JOURNAL OF INFECTIOUS DISEASES

HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon

(2014) Michael A. Chattergoon et al.   PLoS Pathogens

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

(2012) Haitao Wen et al.   NATURE IMMUNOLOGY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Streptococcal M1 protein constructs a pathological host fibrinogen network

(2011) Pauline Macheboeuf et al.   NATURE

Molecular insight into invasive group A streptococcal disease

(2011) Jason N. Cole et al.   NATURE REVIEWS MICROBIOLOGY

Streptococcal M proteins and their role as virulence determinants

(2010) Sonja Oehmcke et al.   CLINICA CHIMICA ACTA

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

(2010) Li-Chung Hsu et al.   NATURE IMMUNOLOGY

Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation

(2009) N. Marina-Garcia et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Activation of the Nlrp3 Inflammasome by Streptococcus pyogenes Requires Streptolysin O and NF- B Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor

(2009) J. Harder et al.   JOURNAL OF IMMUNOLOGY

M1 Protein Allows Group A Streptococcal Survival in Phagocyte Extracellular Traps through Cathelicidin Inhibition

(2009) Xavier Lauth et al.   Journal of Innate Immunity

Global emm type distribution of group A streptococci: systematic review and implications for vaccine development

(2009) Andrew C Steer et al.   LANCET INFECTIOUS DISEASES

Streptolysin O Promotes Group AStreptococcusImmune Evasion by Accelerated Macrophage Apoptosis

(2008) Anjuli M. Timmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil primary granule proteins HBP and HNP1–3 boost bacterial phagocytosis by human and murine macrophages

(2008) Oliver Soehnlein et al.   JOURNAL OF CLINICAL INVESTIGATION

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

(2008) C. McNamara et al.   SCIENCE