Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS
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Title
Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS
Authors
Keywords
Inflammmasome, NLRP3, IL-1beta, HIV-1, FIV, Caspase-1, ASC microglia, Nervous system
Journal
Retrovirology
Volume 11, Issue 1, Pages 35
Publisher
Springer Nature
Online
2014-05-14
DOI
10.1186/1742-4690-11-35
References
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Note: Only part of the references are listed.- Signaling Mechanism of HIV-1 gp120 and Virion-Induced IL-1 Release in Primary Human Macrophages
- (2014) R. Cheung et al. JOURNAL OF IMMUNOLOGY
- Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence
- (2013) Maria J. Polyak et al. FASEB JOURNAL
- Human astrocytes express a novel NLRP2 inflammasome
- (2013) Julia Minkiewicz et al. GLIA
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Monocyte/macrophages and their role in HIV neuropathogenesis
- (2013) Tricia H. Burdo et al. IMMUNOLOGICAL REVIEWS
- HIV-1 Induces the First Signal to Activate the NLRP3 Inflammasome in Monocyte-Derived Macrophages
- (2013) Juan C. Hernandez et al. INTERVIROLOGY
- MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury
- (2013) Nicolas Deroide et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease
- (2013) Amina A. Negash et al. PLoS Pathogens
- Targeting interleukin-1β in CAPS (cryopyrin-associated periodic) syndromes
- (2012) Isabelle Koné-Paut et al. AUTOIMMUNITY REVIEWS
- Neurosteroid-mediated regulation of brain innate immunity in HIV/AIDS: DHEA-S suppresses neurovirulence
- (2012) Ferdinand G. Maingat et al. FASEB JOURNAL
- Integrin α5β1 Activates the NLRP3 Inflammasome by Direct Interaction with a Bacterial Surface Protein
- (2012) Hye-Kyoung Jun et al. IMMUNITY
- Polymorphisms in Inflammasomeʼ Genes and Susceptibility to HIV-1 Infection
- (2012) Alessandra Pontillo et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Innate immunity in the central nervous system
- (2012) Richard M. Ransohoff et al. JOURNAL OF CLINICAL INVESTIGATION
- The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
- (2012) Fushan Shi et al. Journal of Neuroinflammation
- LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner
- (2012) Aedín M Minogue et al. Journal of Neuroinflammation
- Regulation of inflammasome signaling
- (2012) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- Toll-like receptor (TLR) and inflammasome actions in the central nervous system
- (2012) Richa Hanamsagar et al. TRENDS IN IMMUNOLOGY
- IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection
- (2012) Hilario J. Ramos et al. PLoS Pathogens
- Hiding in Plain Sight: How HIV Evades Innate Immune Responses
- (2011) Nicolas Manel et al. CELL
- Neurocognitive dysfunction in the highly active antiretroviral therapy era
- (2011) Nomvuyo Z. Mothobi et al. CURRENT OPINION IN INFECTIOUS DISEASES
- HIV-1 gp120 enhances outward potassium current via CXCR4 and cAMP-dependent protein kinase a signaling in cultured rat microglia
- (2011) Changshui Xu et al. GLIA
- The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release
- (2011) Tobias Hoegen et al. JOURNAL OF IMMUNOLOGY
- HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
- (2011) David C. Goldstone et al. NATURE
- SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
- (2011) Nadine Laguette et al. NATURE
- The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes
- (2011) Rebecca C. Coll et al. PLoS One
- Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence
- (2011) Hong Na et al. Retrovirology
- Innate Sensing of HIV-Infected Cells
- (2011) Alice Lepelley et al. PLoS Pathogens
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- A 3′UTR SNP in NLRP3 Gene is Associated With Susceptibility to HIV-1 Infection
- (2010) Alessandra Pontillo et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Plasmacytoid dendritic cells in HIV infection: striking a delicate balance
- (2010) Patricia Fitzgerald-Bocarsly et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Interleukin 18 in the CNS
- (2010) Silvia Alboni et al. Journal of Neuroinflammation
- The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
- (2010) Nan Yan et al. NATURE IMMUNOLOGY
- Neurologic disease burden in treated HIV/AIDS predicts survival: A population-based study
- (2010) P. Vivithanaporn et al. NEUROLOGY
- Hepatitis C Virus Core Protein Induces Neuroimmune Activation and Potentiates Human Immunodeficiency Virus-1 Neurotoxicity
- (2010) Pornpun Vivithanaporn et al. PLoS One
- Mutant superoxide dismutase 1-induced IL-1 accelerates ALS pathogenesis
- (2010) F. Meissner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome
- (2009) Joseph A. Duncan et al. JOURNAL OF IMMUNOLOGY
- A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury
- (2008) J. P. de Rivero Vaccari et al. JOURNAL OF NEUROSCIENCE
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
- Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections
- (2008) Judith N Mandl et al. NATURE MEDICINE
- HIV Infection of the Central Nervous System: Clinical Features and Neuropathogenesis
- (2008) Lysa Boissé et al. NEUROLOGIC CLINICS
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