Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

Localisation and trafficking of Toll-like receptors: an important mode of regulation

(2010) Anne F McGettrick et al.   CURRENT OPINION IN IMMUNOLOGY

NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice

(2010) X. Kong et al.   JOURNAL OF IMMUNOLOGY

Deletion ofKeap1in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation

(2009) David J. Blake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

(2009) Vincent Paupe et al.   PLoS One

Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4

(2009) T. Roger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

(2009) X. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis

(2009) J. C. Alves-Filho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

(2008) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adverse functions of IL-17A in experimental sepsis

(2008) Michael A. Flierl et al.   FASEB JOURNAL

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

(2008) Karen A. Cavassani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis

(2008) George Plitas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR4-induced IFN-γ production increases TLR2 sensitivity and drives Gram-negative sepsis in mice

(2008) Stephan Spiller et al.   JOURNAL OF EXPERIMENTAL MEDICINE