Principles of early drug discovery

Target discovery from data mining approaches

(2009) Yongliang Yang et al.   DRUG DISCOVERY TODAY

HTS and hit finding in academia – from chemical genomics to drug discovery

(2009) Julie A. Frearson et al.   DRUG DISCOVERY TODAY

Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models

(2009) Kiran Boppana et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The multiple roles of computational chemistry in fragment-based drug design

(2009) Richard Law et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic

(2008) G. Kurosawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA