- Home
- Publications
- Publication Search
- Publication Details
Title
Fibroblasts as Modulators of Local and Systemic Cancer Metabolism
Authors
Keywords
-
Journal
Cancers
Volume 11, Issue 5, Pages 619
Publisher
MDPI AG
Online
2019-05-07
DOI
10.3390/cancers11050619
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tumor-Derived Ligands Trigger Tumor Growth and Host Wasting via Differential MEK Activation
- (2019) Wei Song et al. DEVELOPMENTAL CELL
- A stromal lysolipid-autotaxin signaling axis promotes pancreatic tumor progression
- (2019) Francesca R. Auciello et al. Cancer Discovery
- Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
- (2019) Javier Garcia-Bermudez et al. NATURE
- Stellate Cells in Tissue Repair, Inflammation, and Cancer
- (2018) Mara H. Sherman Annual Review of Cell and Developmental Biology
- PEDF regulates plasticity of a novel lipid–MTOC axis in prostate cancer-associated fibroblasts
- (2018) Francesca Nardi et al. JOURNAL OF CELL SCIENCE
- Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts
- (2018) Linda Ziani et al. Frontiers in Immunology
- Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
- (2018) William J. Sullivan et al. CELL
- Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
- (2018) Laura Hulea et al. Cell Metabolism
- Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis
- (2018) Marion Curtis et al. Cell Metabolism
- Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies
- (2018) Alexander Muir et al. Disease Models & Mechanisms
- Metabolic Signaling to the Nucleus in Cancer
- (2018) Sydney L. Campbell et al. MOLECULAR CELL
- Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
- (2018) Thomas Bertero et al. Cell Metabolism
- Epiregulin induces leptin secretion and energy expenditure in high-fat diet-fed mice
- (2018) Rumana Yasmeen et al. JOURNAL OF ENDOCRINOLOGY
- Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer
- (2018) Yael Raz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma
- (2018) Giulia Biffi et al. Cancer Discovery
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- High Serum Essential Amino Acids as a Predictor of Skeletal Muscle Depletion in Patients With Cachexia and Advanced Gastrointestinal Cancers
- (2017) Moeko Kitagawa et al. NUTRITION IN CLINICAL PRACTICE
- IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma
- (2017) Y Qiao et al. ONCOGENE
- Stromal cues regulate the pancreatic cancer epigenome and metabolome
- (2017) Mara H. Sherman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions
- (2017) Orianne Olivares et al. Nature Communications
- IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
- (2017) Xiongyan Wu et al. Oncotarget
- The reverse Warburg effect is likely to be an Achilles’ heel of cancer that can be exploited for cancer therapy
- (2017) Yaojie Fu et al. Oncotarget
- Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer
- (2017) Luisa Iommarini et al. Frontiers in Oncology
- p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
- (2016) Angeles Duran et al. CANCER CELL
- Metabolic exchanges within tumor microenvironment
- (2016) Paola Chiarugi et al. CANCER LETTERS
- Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer
- (2016) Weimin Wang et al. CELL
- Metabolic Heterogeneity in Human Lung Tumors
- (2016) Christopher T. Hensley et al. CELL
- Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
- (2016) Dan Y. Gui et al. Cell Metabolism
- Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
- (2016) Lifeng Yang et al. Cell Metabolism
- Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity
- (2016) Thomas R. Flint et al. Cell Metabolism
- Mechanisms of metabolic dysfunction in cancer-associated cachexia
- (2016) Michele Petruzzelli et al. GENES & DEVELOPMENT
- sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
- (2016) Amanpreet Kaur et al. NATURE
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- (2016) Cristovão M. Sousa et al. NATURE
- Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells
- (2016) K E Richards et al. ONCOGENE
- Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers
- (2016) J. R. Mayers et al. SCIENCE
- Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis
- (2016) Ya-Ling Hsu et al. Oncotarget
- Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
- (2016) Hongyun Zhao et al. eLife
- Hypoxia and metabolic adaptation of cancer cells
- (2016) K L Eales et al. Oncogenesis
- Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma
- (2016) Martin J. Hicks et al. PLoS One
- Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
- (2015) J. J. Kamphorst et al. CANCER RESEARCH
- Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumour chemoresistance
- (2015) C. Duluc et al. EMBO Molecular Medicine
- Stromal biology and therapy in pancreatic cancer: a changing paradigm
- (2015) Albrecht Neesse et al. GUT
- Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation
- (2015) Daoxiang Zhang et al. Cell Reports
- Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
- (2014) Tania Valencia et al. CANCER CELL
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
- (2014) Serkan Kir et al. NATURE
- Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
- (2014) Jared R Mayers et al. NATURE MEDICINE
- Stromal response to Hedgehog signaling restrains pancreatic cancer progression
- (2014) J. J. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
- (2014) Lahiru Gangoda et al. PROTEOMICS
- Serine and glycine metabolism in cancer
- (2014) Ivano Amelio et al. TRENDS IN BIOCHEMICAL SCIENCES
- Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
- (2013) Y. Zhang et al. CANCER RESEARCH
- Tumor fibroblast–derived epiregulin promotes growth of colitis-associated neoplasms through ERK
- (2013) Clemens Neufert et al. JOURNAL OF CLINICAL INVESTIGATION
- Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
- (2013) Edward W. Roberts et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
- (2013) J. J. Kamphorst et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
- (2013) F. Guillaumond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice
- (2012) M. Tsoli et al. CANCER RESEARCH
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production
- (2012) Carmela Guido et al. CELL CYCLE
- Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways
- (2012) Kenneth C.H. Fearon et al. Cell Metabolism
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- At the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of bone
- (2012) John Foley et al. Odontology
- Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells
- (2011) Y Fuyuhiro et al. BRITISH JOURNAL OF CANCER
- Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
- (2011) Tuanjie Li et al. CANCER LETTERS
- HB-EGF and PDGF Mediate Reciprocal Interactions of Carcinoma Cells with Cancer-Associated Fibroblasts to Support Progression of Uterine Cervical Cancers
- (2011) T. Murata et al. CANCER RESEARCH
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
- (2011) Stephanos Pavlides et al. CELL CYCLE
- Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata
- (2011) Chad E. Brokopp et al. EUROPEAN HEART JOURNAL
- Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment
- (2011) Yanique I. Rattigan et al. EXPERIMENTAL CELL RESEARCH
- Definition and classification of cancer cachexia: an international consensus
- (2011) Kenneth Fearon et al. LANCET ONCOLOGY
- STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia
- (2011) Andrea Bonetto et al. PLoS One
- Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
- (2010) Neta Erez et al. CANCER CELL
- Hallmarks of cancer: Interactions with the tumor stroma
- (2010) Kristian Pietras et al. EXPERIMENTAL CELL RESEARCH
- Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences
- (2010) Virgil Paunescu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
- (2008) Pierre Sonveaux et al. JOURNAL OF CLINICAL INVESTIGATION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More