Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer

Stromal Clusterin Expression Predicts Therapeutic Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

(2018) Yihong Wang et al.   Clinical Breast Cancer

Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial

(2017) Tomasz M Beer et al.   LANCET ONCOLOGY

Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1

(2017) N Cohen et al.   ONCOGENE

The Role of Clusterin in Carcinogenesis and its Potential Utility as Therapeutic Target

(2016) T. Tellez et al.   CURRENT MEDICINAL CHEMISTRY

Carcinoma-associated fibroblasts: orchestrating the composition of malignancy

(2016) Philippe Gascard et al.   GENES & DEVELOPMENT

Downregulation of CXCL12 in mesenchymal stromal cells by TGFβ promotes breast cancer metastasis

(2016) P F Yu et al.   ONCOGENE

Tumor-associated fibroblasts predominantly come from local and not circulating precursors

(2016) Ainhoa Arina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1

(2016) Pedro Barcellos-de-Souza et al.   STEM CELLS

Tumor-Derived Osteopontin Reprograms Normal Mammary Fibroblasts to Promote Inflammation and Tumor Growth in Breast Cancer

(2015) Y. Sharon et al.   CANCER RESEARCH

IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis

(2015) Charles K. Pallangyo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Influence of mesenchymal stem cells on metastasis development in mice in vivo

(2015) Aleksandra V Meleshina et al.   Stem Cell Research & Therapy

PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche

(2015) Guillermo López-Ruano et al.   Stem Cell Reports

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma

(2015) Francois Lamoureux et al.   Oncotarget

Direct contacts with colon cancer cells regulate the differentiation of bone marrow mesenchymal stem cells into tumor associated fibroblasts

(2014) Yanan Peng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

(2014) Brian Ruffell et al.   CANCER CELL

Abstract 5347: MiRNA expression profile of tumor microenvironment in murine liver metastatic model.

(2014) Joana Marquez et al.   CANCER RESEARCH

Fibroblast heterogeneity in the cancer wound

(2014) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clusterin: a key player in cancer chemoresistance and its inhibition

(2014) Tomas Koltai   OncoTargets and Therapy

Cancer Associated Fibroblasts express pro-inflammatory factors in human breast and ovarian tumors

(2013) Neta Erez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer

(2013) L. Bochet et al.   CANCER RESEARCH

Overexpression of clusterin promotes angiogenesis via the vascular endothelial growth factor in primary ovarian cancer

(2013) YANXIA FU et al.   Molecular Medicine Reports

Distinct fibroblast lineages determine dermal architecture in skin development and repair

(2013) Ryan R. Driskell et al.   NATURE

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Multifarious functions of PDGFs and PDGFRs in tumor growth and metastasis

(2013) Yihai Cao   TRENDS IN MOLECULAR MEDICINE

Isolation of Normal and Cancer-associated Fibroblasts from Fresh Tissues by Fluorescence Activated Cell Sorting (FACS)

(2013) Yoray Sharon et al.   Jove-Journal of Visualized Experiments

Clusterin inhibition using OGX-011 synergistically enhances antitumour activity of sorafenib in a human renal cell carcinoma model

(2012) Y Kususda et al.   BRITISH JOURNAL OF CANCER

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Knockdown of clusterin sensitizes pancreatic cancer cells to gemcitabine chemotherapy by ERK1/2 inactivation

(2012) Yong Tang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation

(2012) Charlotte Servais et al.   JOURNAL OF PATHOLOGY

Inhibition of TGF-β/Smad Signaling by BAMBI Blocks Differentiation of Human Mesenchymal Stem Cells to Carcinoma-Associated Fibroblasts and Abolishes their Protumor Effects

(2012) Lei Shangguan et al.   STEM CELLS

Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth

(2011) Michael Quante et al.   CANCER CELL

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

(2011) Zhiyong Mi et al.   CARCINOGENESIS

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Bone marrow-derived mesenchymal stem cells and the tumor microenvironment

(2010) Scott A. Bergfeld et al.   CANCER AND METASTASIS REVIEWS

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

On the origin of cancer-associated fibroblasts

(2010) Charlotte Anderberg et al.   CELL CYCLE

Mesenchymal Stem Cells: Flip Side of the Coin

(2009) Pravin J. Mishra et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts

(2008) C. Anderberg et al.   CANCER RESEARCH

Three-dimensional context regulation of metastasis

(2008) Janine T. Erler et al.   CLINICAL & EXPERIMENTAL METASTASIS

Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting

(2008) Kristian Pietras et al.   PLOS MEDICINE