sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

(2015) J. Yun et al.   SCIENCE

Mitochondrial oxidative stress is the achille’s heel of melanoma cells resistant to Braf-mutant inhibitor

(2015) Paola Corazao-Rozas et al.   Oncotarget

Loss of  -catenin triggers oxidative stress and impairs hematopoietic regeneration

(2014) W. Lento et al.   GENES & DEVELOPMENT

Aging and epigenetic drift: a vicious cycle

(2014) Jean-Pierre Issa   JOURNAL OF CLINICAL INVESTIGATION

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

(2014) Tobias Bald et al.   NATURE

Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53

(2014) Amaya Viros et al.   NATURE

A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors

(2014) D. J. Konieczkowski et al.   Cancer Discovery

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

(2013) P. P. Shah et al.   GENES & DEVELOPMENT

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

(2013) Myriam N. Bouchlaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hypoxia Induces Phenotypic Plasticity and Therapy Resistance in Melanoma via the Tyrosine Kinase Receptors ROR1 and ROR2

(2013) M. P. O'Connell et al.   Cancer Discovery

Biological Aging and Social Characteristics: Gerontology, the Baltimore City Hospitals, and the National Institutes of Health

(2011) H. W. Park   JOURNAL OF THE HISTORY OF MEDICINE AND ALLIED SCIENCES

Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance

(2011) Edward H. Flach et al.   MOLECULAR PHARMACEUTICS

In melanoma, beta-catenin is a suppressor of invasion

(2011) I Arozarena et al.   ONCOGENE

MITF: the power and the glory

(2011) Keith S. Hoek   Pigment Cell & Melanoma Research

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

(2009) A. J. Chien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

MiTF Regulates Cellular Response to Reactive Oxygen Species through Transcriptional Regulation of APE-1/Ref-1

(2008) Feng Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY