Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Extracellular Vesicles and MicroRNAs: Their Role in Tumorigenicity and Therapy for Brain Tumors

(2016) Agnieszka Bronisz et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Manufacturing of recombinant adeno-associated viral vectors for clinical trials

(2016) Nathalie Clément et al.   Molecular Therapy-Methods & Clinical Development

Glioblastoma: pathology, molecular mechanisms and markers

(2015) Kenneth Aldape et al.   ACTA NEUROPATHOLOGICA

Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma

(2015) Francisco Azuaje et al.   Cell Communication and Signaling

New Strategies in Glioblastoma: Exploiting the New Biology

(2015) H. A. Fine   CLINICAL CANCER RESEARCH

Engineering the AAV capsid to optimize vector–host-interactions

(2015) Hildegard Büning et al.   CURRENT OPINION IN PHARMACOLOGY

Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps

(2015) Christina Kober et al.   Journal of Translational Medicine

Sui generis: gene therapy and delivery systems for the treatment of glioblastoma

(2015) J. R. Kane et al.   NEURO-ONCOLOGY

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012

(2015) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

Cytotoxic and immunogenic mechanisms of recombinant oncolytic poliovirus

(2015) Michael C Brown et al.   Current Opinion in Virology

Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates

(2015) Michel Zerah et al.   Human Gene Therapy Clinical Development

Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma

(2014) M J Hicks et al.   CANCER GENE THERAPY

Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma

(2014) A. Omuro et al.   CLINICAL CANCER RESEARCH

Bevacizumab for the treatment of high-grade glioma: an update after Phase III trials

(2014) Mustafa Khasraw et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Adenoviral vector-mediated gene therapy for gliomas: coming of age

(2014) Maria G Castro et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

IND-Directed Safety and Biodistribution Study of Intravenously Injected Cetuximab-IRDye800 in Cynomolgus Macaques

(2014) Kurt R. Zinn et al.   MOLECULAR IMAGING AND BIOLOGY

Adeno-Associated Virus Vectors and Neurological Gene Therapy

(2014) David S. Ojala et al.   NEUROSCIENTIST

EPIDERMAL GROWTH FACTOR RECEPTOR TARGETED THERAPIES FOR SOLID TUMOURS

(2014) M Van den Eynde et al.   ACTA CLINICA BELGICA

Biology of adeno-associated viral vectors in the central nervous system

(2014) Giridhar Murlidharan et al.   Frontiers in Molecular Neuroscience

Systemic gene delivery to the central nervous system using Adeno-associated virus

(2014) Mathieu Bourdenx et al.   Frontiers in Molecular Neuroscience

Comparative Efficacy and Safety of Multiple Routes of Direct CNS Administration of Adeno-Associated Virus Gene Transfer Vector Serotype rh.10 Expressing the Human Arylsulfatase A cDNA to Nonhuman Primates

(2014) Jonathan B. Rosenberg et al.   Human Gene Therapy Clinical Development

Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline

(2013) John R. Goffin et al.   CLINICAL THERAPEUTICS

Brain Bioavailability of Human Intravenous Immunoglobulin and its Transport through the Murine Blood–Brain Barrier

(2013) Isabelle St-Amour et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry techniques

(2013) Daniel Ayoub et al.   mAbs

Humoral Immune Response to AAV

(2013) Roberto Calcedo et al.   Frontiers in Immunology

Strategies in Gene Therapy for Glioblastoma

(2013) Aneta Kwiatkowska et al.   Cancers

Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

(2012) C Allen et al.   GENE THERAPY

The art of gene therapy for glioma: a review of the challenging road to the bedside

(2012) Alex Tobias et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Current status of gene therapy for brain tumors

(2012) Andrea M. Murphy et al.   Translational Research

Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme

(2011) Marie-Thérése Stockhausen et al.   EXPERIMENTAL CELL RESEARCH

Genetic therapy for the nervous system

(2011) W. J. Bowers et al.   HUMAN MOLECULAR GENETICS

AAVrh.10-mediated genetic delivery of bevacizumab to the pleura to provide local anti-VEGF to suppress growth of metastatic lung tumors

(2010) M Watanabe et al.   GENE THERAPY

Gene therapy for high-grade glioma

(2010) Atsushi Natsume et al.   Cell Adhesion & Migration

Directed evolution of adeno-associated virus for glioma cell transduction

(2009) Casey A. Maguire et al.   JOURNAL OF NEURO-ONCOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

(2009) K. Al-Nedawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A New Model for Prediction of Drug Distribution in Tumor and Normal Tissues: Pharmacokinetics of Temozolomide in Glioma Patients

(2008) L. Rosso et al.   CANCER RESEARCH

Tailoring the AAV vector capsid for gene therapy

(2008) L H Vandenberghe et al.   GENE THERAPY

Treatment of Late Infantile Neuronal Ceroid Lipofuscinosis by CNS Administration of a Serotype 2 Adeno-Associated Virus Expressing CLN2 cDNA

(2008) Stefan Worgall et al.   HUMAN GENE THERAPY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY