Dietary Polyphenols—Important Non-Nutrients in the Prevention of Chronic Noncommunicable Diseases. A Systematic Review

Lipid peroxidation diminishing perspective of isolated theaflavins and thearubigins from black tea in arginine induced renal malfunctional rats

(2018) Ali Imran et al.   Lipids in Health and Disease

Glycemic index, glycemic load, and chronic disease risk—a meta-analysis of observational studies

(2018) Alan W Barclay et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Major Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate, Inhibits Obesity, Metabolic Syndrome, and Fatty Liver Disease in High-Fat–Fed Mice

(2018) Mousumi Bose et al.   JOURNAL OF NUTRITION

Quercetin ameliorates chronic unpredicted stress-mediated memory dysfunction in male Swiss albino mice by attenuating insulin resistance and elevating hippocampal GLUT4 levels independent of insulin receptor expression

(2017) Vineet Mehta et al.   HORMONES AND BEHAVIOR

Anticancer and apoptosis-inducing effects of quercetin in vitro and in vivo

(2017) Mahmoud Hashemzaei et al.   ONCOLOGY REPORTS

Hesperidin inhibits ovarian cancer cell viability through endoplasmic reticulum stress signaling pathways

(2017) Jun Zhao et al.   Oncology Letters

Quercetin inhibits angiogenesis-mediated human retinoblastoma growth by targeting vascular endothelial growth factor receptor

(2017) Wei Song et al.   Oncology Letters

A Systematic Review and Meta-Analysis of the Effects of Flavanol-Containing Tea, Cocoa and Apple Products on Body Composition and Blood Lipids: Exploring the Factors Responsible for Variability in Their Efficacy

(2017) Antonio González-Sarrías et al.   Nutrients

Quercetin and Green Tea Extract Supplementation Downregulates Genes Related to Tissue Inflammatory Responses to a 12-Week High Fat-Diet in Mice

(2017) Lynn Cialdella-Kam et al.   Nutrients

Apigenin inhibits renal cell carcinoma cell proliferation

(2017) Shuai Meng et al.   Oncotarget

Research progress on theaflavins: efficacy, formation, and preparation

(2017) Hua-Feng He   Food & Nutrition Research

Type 2 diabetes: A 21st century epidemic

(2016) Lindsay M. Jaacks et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The influence of common free radicals and antioxidants on development of Alzheimer’s Disease

(2016) Karolina A. Wojtunik-Kulesza et al.   BIOMEDICINE & PHARMACOTHERAPY

Recent advances in obesity: the role of turmeric tuber and its metabolites in the prophylaxis and therapeutical strategies

(2016) Agata Jarząb et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1expression

(2016) Tsui-Hwa Tseng et al.   ENVIRONMENTAL TOXICOLOGY

Application of pH-zone refining hydrostatic countercurrent chromatography (hCCC) for the recovery of antioxidant phenolics and the isolation of alkaloids from Siberian barberry herb

(2016) Wirginia Kukula-Koch et al.   FOOD CHEMISTRY

Oxidative challenge in Alzheimer's disease: state of knowledge and future needs

(2016) Carlo Cervellati et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Green tea EGCG, T-cell function, and T-cell-mediated autoimmune encephalomyelitis

(2016) Dayong Wu   JOURNAL OF INVESTIGATIVE MEDICINE

Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling

(2016) Seon-Yeong Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Preventive Effects of Catechins on Cardiovascular Disease

(2016) Xiao-Qiang Chen et al.   MOLECULES

Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice

(2016) Subhayan Sur et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells

(2016) Jin Dai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure

(2016) Shoko Ohno et al.   Scientific Reports

Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma

(2016) Hui-Hui Cao et al.   Scientific Reports

Therapies for Prevention and Treatment of Alzheimer’s Disease

(2016) J. Mendiola-Precoma et al.   Biomed Research International

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Apigenin Attenuates Experimental Autoimmune Myocarditis by Modulating Th1/Th2 Cytokine Balance in Mice

(2015) Shouxin Zhang et al.   INFLAMMATION

Evaluation of thein vitro α-glucosidase inhibitory activity of green tea polyphenols and different tea types

(2015) Xiaoping Yang et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Dietary flavonoid intake and cardiovascular risk: a population-based cohort study

(2015) Valentina Ponzo et al.   Journal of Translational Medicine

The role of leptin in the sporadic form of Alzheimer's disease. Interactions with the adipokines amylin, ghrelin and the pituitary hormone prolactin

(2015) Jaume Folch et al.   LIFE SCIENCES

Biomarkers of Parkinson’s disease: Present and future

(2015) Diane B. Miller et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways

(2015) Ratana Banjerdpongchai et al.   TUMOR BIOLOGY

Dietary intake of specific phenolic compounds and their effect on the antioxidant activity of daily food rations

(2015) Wojciech Koch et al.   Open Chemistry

Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice

(2015) Sanjeev Shukla et al.   PLoS One

Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70–Bax interaction in prostate cancer

(2014) Sanjeev Shukla et al.   APOPTOSIS

The anti-obesity effects of green tea in human intervention and basic molecular studies

(2014) J Huang et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Epigallocatechin-3-gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non-cancerous liver cells

(2014) YUNJUAN ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective effect of quercetin on hyperglycemia, oxidative stress and DNA damage in alloxan induced type 2 diabetic mice

(2014) Md. Maroof Alam et al.   LIFE SCIENCES

Dietary Quercetin Supplementation in Mice Increases Skeletal Muscle PGC1α Expression, Improves Mitochondrial Function and Attenuates Insulin Resistance in a Time-Specific Manner

(2014) Tara M. Henagan et al.   PLoS One

Hesperidin Produces Cardioprotective Activity via PPAR-γ Pathway in Ischemic Heart Disease Model in Diabetic Rats

(2014) Yogeeta O. Agrawal et al.   PLoS One

Beyond Obesity and Lifestyle: A Review of 21st Century Chronic Disease Determinants

(2014) Garry Egger et al.   Biomed Research International

Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer’s Disease

(2013) Filipa I. Baptista et al.   ACS Chemical Neuroscience

Inhibitory effect of catechin-related compounds on renin activity

(2013) Fengjuan LI et al.   BIOMEDICAL RESEARCH-TOKYO

Tea: A new perspective on health benefits

(2013) Marcia da Silva Pinto   FOOD RESEARCH INTERNATIONAL

Quercetin can reduce insulin resistance without decreasing adipose tissue and skeletal muscle fat accumulation

(2013) N. Arias et al.   Genes and Nutrition

Inhibition of NADPH Oxidase by Apocynin Attenuates Progression of Atherosclerosis

(2013) Kara Kinkade et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quercetin differently regulates insulin-mediated glucose transporter 4 translocation under basal and inflammatory conditions in adipocytes

(2013) Manli Xu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary protein and plasma total homocysteine, cysteine concentrations in coronary angiographic subjects

(2013) Yunjun Xiao et al.   Nutrition Journal

Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review

(2013) Janett Barbaresko et al.   NUTRITION REVIEWS

Scientific Validation of the Medicinal Efficacy ofTinospora cordifolia

(2013) Amita Mishra et al.   TheScientificWorldJOURNAL

Chemistry and Biological Activities of Flavonoids: An Overview

(2013) Shashank Kumar et al.   TheScientificWorldJOURNAL

Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications

(2013) Munkyong Pae et al.   Food & Function

Thrombospondin-1 Regulates Blood Flow via CD47 Receptor–Mediated Activation of NADPH Oxidase 1

(2012) Gábor Csányi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apigenin Attenuates 2-Deoxy-D-ribose-Induced Oxidative Cell Damage in HIT-T15 Pancreatic β-Cells

(2012) Kwang Sik Suh et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The dietary flavonoids naringenin and quercetin acutely impair glucose metabolism in rodents possibly via inhibition of hypothalamic insulin signalling

(2012) Christiane E. Koch et al.   BRITISH JOURNAL OF NUTRITION

Improving the Polyphenol Content of Tea

(2012) T. Tounekti et al.   CRITICAL REVIEWS IN PLANT SCIENCES

Influence of extraction procedures on phenolic content and antioxidant activity of Cretan barberry herb

(2012) Wirginia Kukula-Koch et al.   FOOD CHEMISTRY

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Habitual intake of dietary flavonoids and risk of Parkinson disease

(2012) X. Gao et al.   NEUROLOGY

Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients

(2012) Pawel Bogdanski et al.   NUTRITION RESEARCH

Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice

(2012) Soo-Mi Jeong et al.   Nutrition Research and Practice

Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes

(2012) Chang Hwa Jung et al.   PHYTOTHERAPY RESEARCH

Alpha-synuclein: from secretion to dysfunction and death

(2012) O Marques et al.   Cell Death & Disease

Food Sources of Energy and Nutrients among Adults in the US: NHANES 2003–2006

(2012) Carol O'Neil et al.   Nutrients

In Search of a Germ Theory Equivalent for Chronic Disease

(2012) G Egger   Preventing Chronic Disease

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet

(2011) Peng Pu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dietary Antioxidants: Immunity and Host Defense

(2011) Maria A. Puertollano et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Effects of Vitamin Treatment or Supplements with Purported Antioxidant Properties on Skin Cancer Prevention: A Meta-Analysis of Randomized Controlled Trials

(2011) Yoon Jung Chang et al.   DERMATOLOGY

Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension

(2011) Manuel Gómez-Guzmán et al.   FREE RADICAL BIOLOGY AND MEDICINE

The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects

(2010) Joshua Tarini et al.   Applied Physiology Nutrition and Metabolism

The history of the cholinergic hypothesis

(2010) Antonio Contestabile   BEHAVIOURAL BRAIN RESEARCH

Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR)

(2010) Song Yi Bae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet

(2010) Remko S. Kuipers et al.   BRITISH JOURNAL OF NUTRITION

99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Darwinian medicine and the ‘hygiene’ or ‘old friends’ hypothesis

(2010) G. A. W. Rook   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Identification of the 100 richest dietary sources of polyphenols: an application of the Phenol-Explorer database

(2010) J Pérez-Jiménez et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

(2010) Wan Namkung et al.   FASEB JOURNAL

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

(2010) Adam Smith et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Systematic Analysis of the Content of 502 Polyphenols in 452 Foods and Beverages: An Application of the Phenol-Explorer Database

(2010) Jara Pérez-Jiménez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary Hesperidin Exerts Hypoglycemic and Hypolipidemic Effects in Streptozotocin-Induced Marginal Type 1 Diabetic Rats

(2010) Satoko Akiyama et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Pharmacokinetics and Tissue Distribution of 14C-Labeled Grape Polyphenols in the Periphery and the Central Nervous System Following Oral Administration

(2010) Elsa M. Janle et al.   JOURNAL OF MEDICINAL FOOD

The effects of theaflavin-enriched black tea extract on muscle soreness, oxidative stress, inflammation, and endocrine responses to acute anaerobic interval training: a randomized, double-blind, crossover study

(2010) Shawn M Arent et al.   Journal of the International Society of Sports Nutrition

Stimulation of AMP-activated protein kinase and enhancement of basal glucose uptake in muscle cells by quercetin and quercetin glycosides, active principles of the antidiabetic medicinal plant Vaccinium vitis-idaea

(2010) Hoda M. Eid et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Diet and Inflammation

(2010) Leo Galland   NUTRITION IN CLINICAL PRACTICE

Non-nutrient causes of low-grade, systemic inflammation: support for a ‘canary in the mineshaft’ view of obesity in chronic disease

(2010) G. Egger et al.   Obesity Reviews

Antihyperglycaemic and protective effects of flavonoids on streptozotocin-induced diabetic rats

(2010) Amélia P. Rauter et al.   PHYTOTHERAPY RESEARCH

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenol-Explorer: an online comprehensive database on polyphenol contents in foods

(2010) V. Neveu et al.   Database-The Journal of Biological Databases and Curation

Sleep Duration in the United States: A Cross-sectional Population-based Study

(2009) P. M. Krueger et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Phenolic Compounds Prevent Alzheimer’s Pathology through Different Effects on the Amyloid-β Aggregation Pathway

(2009) Tsuyoshi Hamaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Vitamin D and the evolution of human depigmentation

(2009) George Chaplin et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

(2009) H. Kolb et al.   DIABETOLOGIA

Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models

(2009) Damla Pinar Karpinar et al.   EMBO JOURNAL

Luteolin enhances insulin sensitivity via activation of PPARγ transcriptional activity in adipocytes

(2009) Li Ding et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary quercetin alleviates diabetic symptoms and reduces streptozotocin-induced disturbance of hepatic gene expression in mice

(2009) Msauko Kobori et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammatory effects of nutritional stimuli: further support for the need for a big picture approach to tackling obesity and chronic disease

(2009) G. Egger et al.   Obesity Reviews

Hesperidin suppressed proliferations of both Human breast cancer and androgen-dependent prostate cancer cells

(2009) Choong Jae Lee et al.   PHYTOTHERAPY RESEARCH

Reduced Sleep Duration or Quality: Relationships With Insulin Resistance and Type 2 Diabetes

(2009) Esra Tasali et al.   PROGRESS IN CARDIOVASCULAR DISEASES

The Preventable Causes of Death in the United States: Comparative Risk Assessment of Dietary, Lifestyle, and Metabolic Risk Factors

(2009) Goodarz Danaei et al.   PLOS MEDICINE

Apigenin inhibited migration and invasion of human ovarian cancer A2780 cells through focal adhesion kinase

(2008) X.-W. Hu et al.   CARCINOGENESIS

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(2008) Herbert Tilg et al.   MOLECULAR MEDICINE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Oxidative and Inflammatory Pathways in Parkinson’s Disease

(2008) Rebecca L. Miller et al.   NEUROCHEMICAL RESEARCH

Adverse cardiovascular effects of air pollution

(2008) Nicholas L Mills et al.   Nature clinical practice. Cardiovascular medicine

The epidemiological transition: the current status of infectious diseases in the developed world versus the developing world

(2008) John W. Sanders et al.   SCIENCE PROGRESS

Brain iron pathways and their relevance to Parkinson's disease

(2003) D Berg et al.   JOURNAL OF NEUROCHEMISTRY