Quercetin and Green Tea Extract Supplementation Downregulates Genes Related to Tissue Inflammatory Responses to a 12-Week High Fat-Diet in Mice

The Major Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate, Inhibits Obesity, Metabolic Syndrome, and Fatty Liver Disease in High-Fat–Fed Mice

(2018) Mousumi Bose et al.   JOURNAL OF NUTRITION

Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by PI3K-AKT signaling in 3T3-L1 cells

(2017) Mengqing Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?

(2017) Shirin Pournourmohammadi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Quercetin, a functional compound of onion peel, remodels white adipocytes to brown-like adipocytes

(2017) Sang Gil Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Epigallocatechin-3-gallate ameliorates insulin resistance in hepatocytes

(2017) Shan-Bo Ma et al.   Molecular Medicine Reports

EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation ofDnmt1andMLH1in C57BL/6J Male Mice

(2017) Marlene Remely et al.   Oxidative Medicine and Cellular Longevity

Effects of green tea supplementation on inflammation markers, antioxidant status and blood pressure in NaCl-induced hypertensive rat model

(2017) Monika Szulińska et al.   Food & Nutrition Research

Quercetin lowers plasma uric acid in pre-hyperuricaemic males: a randomised, double-blinded, placebo-controlled, cross-over trial

(2016) Yuanlu Shi et al.   BRITISH JOURNAL OF NUTRITION

Stress Hyperglycemia During Surgery and Anesthesia: Pathogenesis and Clinical Implications

(2016) Nadine E. Palermo et al.   Current Diabetes Reports

Effects of Quercetin on Adiponectin-Mediated Insulin Sensitivity in Polycystic Ovary Syndrome: A Randomized Placebo-Controlled Double-Blind Clinical Trial

(2016) N. Rezvan et al.   HORMONE AND METABOLIC RESEARCH

Consumption of Quercetin and Quercetin-Containing Apple and Cherry Extracts Affects Blood Glucose Concentration, Hepatic Metabolism, and Gene Expression Patterns in Obese C57BL/6J High Fat–Fed Mice

(2016) Sarah M Snyder et al.   JOURNAL OF NUTRITION

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

A Mixed Flavonoid-Fish Oil Supplement Induces Immune-Enhancing and Anti-Inflammatory Transcriptomic Changes in Adult Obese and Overweight Women—A Randomized Controlled Trial

(2016) Lynn Cialdella-Kam et al.   Nutrients

Quercetin Ameliorates Experimental Autoimmune Myocarditis in Rats

(2016) Marina Milenković et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Evaluation of the appropriateness of using glucometers for measuring the blood glucose levels in mice

(2016) Yu Togashi et al.   Scientific Reports

Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial

(2015) Verena Brüll et al.   BRITISH JOURNAL OF NUTRITION

Quercetin: A flavonol with multifaceted therapeutic applications?

(2015) Gabriele D'Andrea   FITOTERAPIA

From neutrophils to macrophages: differences in regional adipose tissue depots

(2015) V. Dam et al.   Obesity Reviews

Omega-3 fatty acids and inflammation: A perspective on the challenges of evaluating efficacy in clinical research

(2015) Ann C. Skulas-Ray   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials

(2014) Saman Khalesi et al.   EUROPEAN JOURNAL OF NUTRITION

Organic anion transporting polypeptides and organic cation transporter 1 contribute to the cellular uptake of the flavonoid quercetin

(2014) Hartmut Glaeser et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The effect of green tea on blood pressure and lipid profile: A systematic review and meta-analysis of randomized clinical trials

(2014) I. Onakpoya et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Epigallocatechin-3-gallate inhibits angiotensin II and interleukin-6-induced C-reactive protein production in macrophages

(2014) Ming Li et al.   Pharmacological Reports

Dietary Quercetin Supplementation in Mice Increases Skeletal Muscle PGC1α Expression, Improves Mitochondrial Function and Attenuates Insulin Resistance in a Time-Specific Manner

(2014) Tara M. Henagan et al.   PLoS One

Effect of green tea consumption on blood pressure: A meta-analysis of 13 randomized controlled trials

(2014) Xiaoli Peng et al.   Scientific Reports

Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials

(2013) Kai Liu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Modulation of adipose tissue inflammation by bioactive food compounds

(2013) Nalin Siriwardhana et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Green Tea Supplementation Affects Body Weight, Lipids, and Lipid Peroxidation in Obese Subjects with Metabolic Syndrome

(2013) Arpita Basu et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Green Tea Extract Supplementation Induces the Lipolytic Pathway, Attenuates Obesity, and Reduces Low-Grade Inflammation in Mice Fed a High-Fat Diet

(2013) Cláudio A. Cunha et al.   MEDIATORS OF INFLAMMATION

The Effect of High-Fat Diet-Induced Pathophysiological Changes in the Gut on Obesity: What Should be the Ideal Treatment?

(2013) Chooi Y Lee   Clinical and Translational Gastroenterology

The Effects of Green Tea on Obesity and Type 2 Diabetes

(2013) Hyun Min Kim et al.   Diabetes & Metabolism Journal

Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats

(2012) Qing-Hua Hu et al.   BIOCHEMICAL PHARMACOLOGY

Impact of Obesity on Drug Metabolism and Elimination in Adults and Children

(2012) Margreke J.E. Brill et al.   CLINICAL PHARMACOKINETICS

Opposite Effects of Quercetin, Luteolin, and Epigallocatechin Gallate on Insulin Sensitivity Under Normal and Inflammatory Conditions in Mice

(2012) Lu Shao et al.   INFLAMMATION

Transcriptomic and Metabonomic Profiling Reveal Synergistic Effects of Quercetin and Resveratrol Supplementation in High Fat Diet Fed Mice

(2012) Mingmei Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial

(2012) Simone Schmidt et al.   Lipids in Health and Disease

‘Sarcobesity’: A metabolic conundrum

(2012) Evelyn B. Parr et al.   MATURITAS

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

(2012) Saswata Talukdar et al.   NATURE MEDICINE

Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes

(2012) Chang Hwa Jung et al.   PHYTOTHERAPY RESEARCH

Quercetin increased bioavailability and decreased methylation of green tea polyphenols in vitro and in vivo

(2012) Piwen Wang et al.   Food & Function

Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials

(2011) Xin-Xin Zheng et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Quercetin with vitamin C and niacin does not affect body mass or composition

(2011) Amy M. Knab et al.   Applied Physiology Nutrition and Metabolism

Interactions of Green Tea Catechins with Organic Anion-Transporting Polypeptides

(2011) M. Roth et al.   DRUG METABOLISM AND DISPOSITION

Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?

(2011) Derliz Mereles et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media

(2011) A Overman et al.   INTERNATIONAL JOURNAL OF OBESITY

Suppression of Free Fatty Acid-Induced Insulin Resistance by Phytopolyphenols in C2C12 Mouse Skeletal Muscle Cells

(2011) Yea-Tzy Deng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Influence of Quercetin Supplementation on Disease Risk Factors in Community-Dwelling Adults

(2011) Amy M. Knab et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Green Tea Catechins Decrease Total and Low-Density Lipoprotein Cholesterol: A Systematic Review and Meta-Analysis

(2011) Amie Kim et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Polyphenols: Planting the seeds of treatment for the metabolic syndrome

(2011) E. Paul Cherniack   NUTRITION

Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-α–mediated inflammation and insulin resistance in primary human adipocytes

(2010) Chia-Chi Chuang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach

(2010) Gertruud CM Bakker et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A 12-week supplementation with quercetin does not affect natural killer cell activity, granulocyte oxidative burst activity or granulocyte phagocytosis in female human subjects

(2010) Serena A. Heinz et al.   BRITISH JOURNAL OF NUTRITION

Fruit polyphenols, immunity and inflammation

(2010) Javier González-Gallego et al.   BRITISH JOURNAL OF NUTRITION

Laboratory, Epidemiological, and Human Intervention Studies Show That Tea (Camellia sinensis) May Be Useful in the Prevention of Obesity

(2010) Kimberly A. Grove et al.   JOURNAL OF NUTRITION

Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice

(2010) Masuko Kobori et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Role of (−)-epigallocatechin-3-gallate in cell viability, lipogenesis, and retinol-binding protein 4 expression in adipocytes

(2010) Hye-Young Sung et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome

(2010) Arpita Basu et al.   NUTRITION

Quercetin supplementation and upper respiratory tract infection: A randomized community clinical trial

(2010) Serena A. Heinz et al.   PHARMACOLOGICAL RESEARCH

Weight control and prevention of metabolic syndrome by green tea

(2010) Sudathip Sae-tan et al.   PHARMACOLOGICAL RESEARCH

Metabolic fate of polyphenols in the human superorganism

(2010) J. van Duynhoven et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study

(2009) Sarah Egert et al.   BRITISH JOURNAL OF NUTRITION

Effects of Quercetin and EGCG on Mitochondrial Biogenesis and Immunity

(2009) DAVID C. NIEMAN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

(-)-Epigallocatechin gallate enhances the expression of genes related to insulin sensitivity and adipocyte differentiation in 3T3-L1 adipocytes at an early stage of differentiation

(2009) Naoko Sakurai et al.   NUTRITION

Epigallocatechin gallate promotes GLUT4 translocation in skeletal muscle

(2008) Manabu Ueda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways

(2008) Jiyun Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial

(2008) A. Louise Brown et al.   BRITISH JOURNAL OF NUTRITION

Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity

(2008) Xian-Kang Fang et al.   LIFE SCIENCES

Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet

(2008) Laura K. Stewart et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats

(2008) Leonor Rivera et al.   Obesity

Inhibitory effects of green tea catechin on the lipid accumulation in 3T3-L1 adipocytes

(2008) Mak-Soon Lee et al.   PHYTOTHERAPY RESEARCH