Rapid characterization of structural and functional similarity for a candidate bevacizumab (Avastin) biosimilar using a multipronged mass‐spectrometry‐based approach
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Rapid characterization of structural and functional similarity for a candidate bevacizumab (Avastin) biosimilar using a multipronged mass‐spectrometry‐based approach
Authors
Keywords
-
Journal
Drug Testing and Analysis
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-05-01
DOI
10.1002/dta.2609
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The growing role of structural mass spectrometry in the discovery and development of therapeutic antibodies
- (2018) Yuwei Tian et al. ANALYST
- Signature of Antibody Domain Exchange by Native Mass Spectrometry and Collision-Induced Unfolding
- (2018) Yasunori Watanabe et al. ANALYTICAL CHEMISTRY
- Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products
- (2017) Marco Tassi et al. JOURNAL OF SEPARATION SCIENCE
- Resolving the micro-heterogeneity and structural integrity of monoclonal antibodies by hybrid mass spectrometric approaches
- (2017) Yang Yang et al. mAbs
- Distinct Dynamic Modes Enable the Engagement of Dissimilar Ligands in a Promiscuous Atypical RNA Recognition Motif
- (2016) Kerene A. Brown et al. BIOCHEMISTRY
- Comparative higher-order structure analysis of antibody biosimilars using combined bottom-up and top-down hydrogen-deuterium exchange mass spectrometry
- (2016) Jingxi Pan et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- FDA's Approach to Regulating Biosimilars
- (2016) Steven J. Lemery et al. CLINICAL CANCER RESEARCH
- Evaluation of Ion Mobility-Mass Spectrometry for Comparative Analysis of Monoclonal Antibodies
- (2016) Carly N. Ferguson et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Evaluation of the structural, physicochemical, and biological characteristics of SB4, a biosimilar of etanercept
- (2016) Ick Hyun Cho et al. mAbs
- Advanced assessment of the physicochemical characteristics of Remicade® and Inflectra® by sensitive LC/MS techniques
- (2016) Jing Fang et al. mAbs
- Higher-order structural interrogation of antibodies using middle-down hydrogen/deuterium exchange mass spectrometry
- (2016) Jingxi Pan et al. Chemical Science
- Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures
- (2015) Yuwei Tian et al. ANALYTICAL CHEMISTRY
- Structure, Dynamics, Assembly, and Evolution of Protein Complexes
- (2015) Joseph A. Marsh et al. Annual Review of Biochemistry
- Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies
- (2015) Alain Beck et al. JOURNAL OF MASS SPECTROMETRY
- Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins
- (2015) Liming Liu JOURNAL OF PHARMACEUTICAL SCIENCES
- Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate
- (2015) Julien Marcoux et al. PROTEIN SCIENCE
- Quantifying the stabilizing effects of protein–ligand interactions in the gas phase
- (2015) Timothy M. Allison et al. Nature Communications
- Hyperphosphorylation of Intrinsically Disordered Tau Protein Induces an Amyloidogenic Shift in Its Conformational Ensemble
- (2015) Shaolong Zhu et al. PLoS One
- Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry
- (2014) Richard Y.-C. Huang et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Rapid comparison of a candidate biosimilar to an innovator monoclonal antibody with advanced liquid chromatography and mass spectrometry technologies
- (2014) Hongwei Xie et al. mAbs
- Bioanalytical strategy used in development of pharmacokinetic (PK) methods that support biosimilar programs
- (2014) Alex Colbert et al. mAbs
- Detailed mass analysis of structural heterogeneity in monoclonal antibodies using native mass spectrometry
- (2014) Sara Rosati et al. Nature Protocols
- In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap
- (2013) Sara Rosati et al. mAbs
- Performing native mass spectrometry analysis on therapeutic antibodies
- (2013) Natalie J. Thompson et al. METHODS
- Characterization of Therapeutic Antibodies and Related Products
- (2012) Alain Beck et al. ANALYTICAL CHEMISTRY
- Measuring Dynamics in Weakly Structured Regions of Proteins Using Microfluidics-Enabled Subsecond H/D Exchange Mass Spectrometry
- (2012) Tamanna Rob et al. ANALYTICAL CHEMISTRY
- Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry
- (2012) Alain Beck et al. ANALYTICAL CHEMISTRY
- Native ion mobility-mass spectrometry and related methods in structural biology
- (2012) A. Konijnenberg et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Therapeutic Recombinant Monoclonal Antibodies
- (2012) Ray Bakhtiar JOURNAL OF CHEMICAL EDUCATION
- The impact of glycosylation on monoclonal antibody conformation and stability
- (2012) Kai Zheng et al. mAbs
- Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars
- (2012) Steven A. Berkowitz et al. NATURE REVIEWS DRUG DISCOVERY
- RIBBON-1: Randomized, Double-Blind, Placebo-Controlled, Phase III Trial of Chemotherapy With or Without Bevacizumab for First-Line Treatment of Human Epidermal Growth Factor Receptor 2–Negative, Locally Recurrent or Metastatic Breast Cancer
- (2011) Nicholas J. Robert et al. JOURNAL OF CLINICAL ONCOLOGY
- Worldwide experience with biosimilar development
- (2011) Mark McCamish et al. mAbs
- Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer
- (2011) Robert A. Burger et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies
- (2010) Damian Houde et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Ion mobility–mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation
- (2010) Christian Bleiholder et al. Nature Chemistry
- Extending Mass Spectrometry Contribution to Therapeutic Monoclonal Antibody Lead Optimization: Characterization of Immune Complexes Using Noncovalent ESI-MS
- (2009) Cédric Atmanene et al. ANALYTICAL CHEMISTRY
- Therapeutic antibodies: successes, limitations and hopes for the future
- (2009) Patrick Chames et al. BRITISH JOURNAL OF PHARMACOLOGY
- Deciphering Drift Time Measurements from Travelling Wave Ion Mobility Spectrometry-Mass Spectrometry Studies
- (2009) David P. Smith et al. EUROPEAN JOURNAL OF MASS SPECTROMETRY
- Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer
- (2009) Pavel V. Bondarenko et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab
- (2009) Carola W. N. Damen et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action
- (2009) Royston Jefferis TRENDS IN PHARMACOLOGICAL SCIENCES
- Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins
- (2008) Alain Beck et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Ion mobility-mass spectrometry
- (2008) Abu B. Kanu et al. JOURNAL OF MASS SPECTROMETRY
- Ion mobility adds an additional dimension to mass spectrometric analysis of solution-phase hydrogen/deuterium exchange
- (2008) Roxana E. Iacob et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started