Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab

Selective identification and differentiation of N-and O-linked oligosaccharides in glycoproteins by liquid chromatography-mass spectrometry

(2010) Steven A. Carr et al.   PROTEIN SCIENCE

Glycosylation profiling of a therapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer

(2008) Amareth Lim et al.   ANALYTICAL BIOCHEMISTRY

Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells

(2008) Panagiotis Karagiannis et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Evaluation of glycosylation for quality assurance of antibody pharmaceuticals by capillary electrophoresis

(2008) Satoru Kamoda et al.   ELECTROPHORESIS

Comparison of LC and LC/MS methods for quantifying N-glycosylation in recombinant IgGs

(2008) Sandipan Sinha et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Quantitative aspects of the analysis of the monoclonal antibody trastuzumab using high-performance liquid chromatography coupled with electrospray mass spectrometry

(2007) Carola W.N. Damen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Determination of N-glycosylation sites and site heterogeneity in a monoclonal antibody by electrospray quadrupole ion-mobility time-of-flight mass spectrometry

(2007) Petra Olivova et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS