In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap

Development of a Native Nanoelectrospray Mass Spectrometry Method for Determination of the Drug-to-Antibody Ratio of Antibody–Drug Conjugates

(2013) Jia Chen et al.   ANALYTICAL CHEMISTRY

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG

(2013) Rebecca J. Rose et al.   mAbs

Performing native mass spectrometry analysis on therapeutic antibodies

(2013) Natalie J. Thompson et al.   METHODS

Proteoform: a single term describing protein complexity

(2013) Lloyd M Smith et al.   NATURE METHODS

Qualitative and Semiquantitative Analysis of Composite Mixtures of Antibodies by Native Mass Spectrometry

(2012) Sara Rosati et al.   ANALYTICAL CHEMISTRY

Characterization of Therapeutic Antibodies and Related Products

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

Native Intact Mass Determination of Antibodies Conjugated with Monomethyl Auristatin E and F at Interchain Cysteine Residues

(2012) John F. Valliere-Douglass et al.   ANALYTICAL CHEMISTRY

Direct Approach for Qualitative and Quantitative Characterization of Glycoproteins Using Tandem Mass Tags and an LTQ Orbitrap XL Electron Transfer Dissociation Hybrid Mass Spectrometer

(2012) Hongping Ye et al.   ANALYTICAL CHEMISTRY

Exploring an Orbitrap Analyzer for the Characterization of Intact Antibodies by Native Mass Spectrometry

(2012) Sara Rosati et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibody-Drug Conjugates in Cancer Therapy

(2012) Eric L. Sievers et al.   Annual Review of Medicine

Structure of the O-Glycosylated Conopeptide CcTx fromConus consorsVenom

(2012) Henry G. Hocking et al.   CHEMISTRY-A EUROPEAN JOURNAL

Strategies for the profiling, characterisation and detailed structural analysis of N-linked oligosaccharides

(2012) Tharmala Tharmalingam et al.   GLYCOCONJUGATE JOURNAL

N- and O-Glycosylation of a Commercial Bovine Whey Protein Product

(2012) Sander S. van Leeuwen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Rapid evaluation for heterogeneities in monoclonal antibodies by liquid chromatography/mass spectrometry with a column-switching system

(2012) Ryosuke Kuribayashi et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Higher Energy Collision Dissociation (HCD) Product Ion-Triggered Electron Transfer Dissociation (ETD) Mass Spectrometry for the Analysis of N-Linked Glycoproteins

(2012) Charandeep Singh et al.   JOURNAL OF PROTEOME RESEARCH

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies

(2012) Rebecca J Rose et al.   NATURE METHODS

A MALDI-TOF MS method for the simultaneous and quantitative analysis of neutral and sialylated glycans of CHO-expressed glycoproteins

(2011) Samnang Tep et al.   CARBOHYDRATE RESEARCH

Recent advances in hydrophilic interaction liquid chromatography (HILIC) for structural glycomics

(2011) Gerhild Zauner et al.   ELECTROPHORESIS

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry

(2011) Rebecca J. Rose et al.   STRUCTURE

High Throughput Quantification of N-Glycans Using One-Pot Sialic Acid Modification and Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry

(2010) Geun-Cheol Gil et al.   ANALYTICAL CHEMISTRY

Simultaneous Glycan-Peptide Characterization Using Hydrophilic Interaction Chromatography and Parallel Fragmentation by CID, Higher Energy Collisional Dissociation, and Electron Transfer Dissociation MS Applied to theN-Linked Glycoproteome ofCampylobacter jejuni

(2010) Nichollas E. Scott et al.   MOLECULAR & CELLULAR PROTEOMICS

Terminal sugars of Fc glycans influence antibody effector functions of IgGs

(2008) T Shantha Raju   CURRENT OPINION IN IMMUNOLOGY

On-line separations combined with MS for analysis of glycosaminoglycans

(2008) Joseph Zaia   MASS SPECTROMETRY REVIEWS

Native mass spectrometry: a bridge between interactomics and structural biology

(2008) Albert J R Heck   NATURE METHODS

Identification of a receptor required for the anti-inflammatory activity of IVIG

(2008) R. M. Anthony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

(2008) R. M. Anthony et al.   SCIENCE

Determination of N-glycosylation sites and site heterogeneity in a monoclonal antibody by electrospray quadrupole ion-mobility time-of-flight mass spectrometry

(2007) Petra Olivova et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS