Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies
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Title
Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies
Authors
Keywords
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Journal
Frontiers in Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-02-28
DOI
10.3389/fnins.2019.00164
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Note: Only part of the references are listed.- Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells
- (2018) Martina Zandl-Lang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Clusterin Reduces Cold Ischemia-Reperfusion Injury in Heart Transplantation Through Regulation of NF-kB Signaling and Bax/Bcl-xL Expression
- (2018) Guodong Liu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Associations of plasma clusterin and Alzheimer’s disease-related MRI markers in adults at mid-life: The CARDIA Brain MRI sub-study
- (2018) Thaddeus Haight et al. PLoS One
- Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis
- (2018) Lizzy Peix et al. Scientific Reports
- Association of the Alzheimer's Disease Clusterin Risk Allele with Plasma Clusterin Concentration
- (2018) Britta Schürmann et al. JOURNAL OF ALZHEIMERS DISEASE
- Blood Clusterin Levels, rs9331888 Polymorphism, and the Risk of Alzheimer's Disease
- (2018) Yao-Yao Xing et al. JOURNAL OF ALZHEIMERS DISEASE
- Association of K832R and R952K SNPs of Wilson's Disease Gene with Alzheimer's Disease
- (2018) Serena Bucossi et al. JOURNAL OF ALZHEIMERS DISEASE
- Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons
- (2018) Jacqueline P. Robbins et al. Frontiers in Neuroscience
- Common Variants in PLXNA4 and Correlation to CSF-related Phenotypes in Alzheimer's Disease
- (2018) Qiu Han et al. Frontiers in Neuroscience
- Pseudoexfoliation and Alzheimer’s associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression
- (2017) Biswajit Padhy et al. HUMAN MOLECULAR GENETICS
- Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial
- (2017) Kim N Chi et al. LANCET ONCOLOGY
- Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
- (2017) Tomasz M Beer et al. LANCET ONCOLOGY
- Correlation of rs9331888 polymorphism with Alzheimer’s disease among Caucasian and Chinese populations: a meta-analysis and systematic review
- (2017) Bin Zhu et al. METABOLIC BRAIN DISEASE
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
- (2017) Rebecca Sims et al. NATURE GENETICS
- Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways
- (2017) Aleksandra M. Wojtas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clusterin protects neurons against intracellular proteotoxicity
- (2017) Jenna M. Gregory et al. Acta Neuropathologica Communications
- 2016 Alzheimer's disease facts and figures
- (2016) Alzheimers & Dementia
- Impact ofPICALMandCLUon hippocampal degeneration
- (2016) Xianfeng Yang et al. HUMAN BRAIN MAPPING
- Identification of plexin A4 as a novel clusterin receptor links two Alzheimer’s disease risk genes
- (2016) Silvia S. Kang et al. HUMAN MOLECULAR GENETICS
- Modulation of Amyloid-β1–40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier
- (2016) Cristina Merino-Zamorano et al. JOURNAL OF ALZHEIMERS DISEASE
- The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort
- (2016) Merve Alaylıoğlu et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- Metallo-pathways to Alzheimer's disease: lessons from genetic disorders of copper trafficking
- (2016) M. A. Greenough et al. Metallomics
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Association between clusterin gene polymorphism rs11136000 and late-onset Alzheimer's disease susceptibility: A review and meta-analysis of case-control studies
- (2016) Wenjin Du et al. Experimental and Therapeutic Medicine
- Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts
- (2016) Lin Tan et al. Scientific Reports
- Plasma Clusterin and the CLU Gene rs11136000 Variant Are Associated with Mild Cognitive Impairment in Type 2 Diabetic Patients
- (2016) Rongrong Cai et al. Frontiers in Aging Neuroscience
- Alzheimer's disease risk variant in CLU is associated with neural inefficiency in healthy individuals
- (2015) Thomas M. Lancaster et al. Alzheimers & Dementia
- Clusterin gene is predominantly regulated by histone modifications in human colon cancer and ectopic expression of the nuclear isoform induces cell death
- (2015) Moonmoon Deb et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Exploring the possible link between MeCP2 and oxidative stress in Rett syndrome
- (2015) Stefania Filosa et al. FREE RADICAL BIOLOGY AND MEDICINE
- The genetic landscape of Alzheimer disease: clinical implications and perspectives
- (2015) Caroline Van Cauwenberghe et al. GENETICS IN MEDICINE
- Exosomal clusterin, identified in the pericardial fluid, improves myocardial performance following MI through epicardial activation, enhanced arteriogenesis and reduced apoptosis
- (2015) Eleonora Foglio et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- CLU rs9331888 Polymorphism Contributes to Alzheimer’s Disease Susceptibility in Caucasian But Not East Asian Populations
- (2015) Shuyan Zhang et al. MOLECULAR NEUROBIOLOGY
- Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations
- (2015) Karolien Bettens et al. Molecular Neurodegeneration
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Late-onset Alzheimer’s risk variants in memory decline, incident mild cognitive impairment, and Alzheimer’s disease
- (2015) Minerva M. Carrasquillo et al. NEUROBIOLOGY OF AGING
- Genetic associations of CLU rs9331888 polymorphism with Alzheimer’s disease: A meta-analysis
- (2015) Ping Shuai et al. NEUROSCIENCE LETTERS
- Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation
- (2015) Nuala A. O'Leary et al. NUCLEIC ACIDS RESEARCH
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- (2015) Angela Baralla et al. PLoS One
- Increased extracellular clusterin in the prefrontal cortex in schizophrenia
- (2015) Katina M. Athanas et al. SCHIZOPHRENIA RESEARCH
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- (2015) Teresia Hallström et al. PLoS One
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- (2014) X. Liu et al. Acta Physiologica
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- (2014) Gyungah Jun et al. ANNALS OF NEUROLOGY
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- (2014) Priyanka Narayan et al. BIOCHEMISTRY
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- (2014) Peng Zhang et al. Brain Structure & Function
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- (2014) Philipp Rohne et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
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- (2014) Biswajit Padhy et al. EXPERIMENTAL EYE RESEARCH
- The role of epigenetics in age-related macular degeneration
- (2014) M Gemenetzi et al. EYE
- Two Alzheimer’s disease risk genes increase entorhinal cortex volume in young adults
- (2014) Amanda Marie DiBattista et al. Frontiers in Human Neuroscience
- Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microgliain vitro
- (2014) Sandra D. Mulder et al. GLIA
- CLU rs2279590 polymorphism contributes to Alzheimer’s disease susceptibility in Caucasian and Asian populations
- (2014) Shuyan Zhang et al. JOURNAL OF NEURAL TRANSMISSION
- Molecular Profiles of Pyramidal Neurons in the Superior Temporal Cortex in Schizophrenia
- (2014) Charmaine Y. Pietersen et al. JOURNAL OF NEUROGENETICS
- Molecular Profiles of Parvalbumin-Immunoreactive Neurons in the Superior Temporal Cortex in Schizophrenia
- (2014) Charmaine Y. Pietersen et al. JOURNAL OF NEUROGENETICS
- Combined Effects of Alzheimer Risk Variants in the CLU and ApoE Genes on Ventricular Expansion Patterns in the Elderly
- (2014) F. F. Roussotte et al. JOURNAL OF NEUROSCIENCE
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Inhibition of Intracellular Clusterin Attenuates Cell Death in Nephropathic Cystinosis
- (2014) P. Sansanwal et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings
- (2014) Samantha L. Rosenthal et al. PLoS One
- Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease
- (2014) Yuan Zhou et al. PLoS One
- Many players in BCL-2 family affairs
- (2014) Tudor Moldoveanu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival
- (2014) Fan Zhang et al. Nature Communications
- Complement activation in multiple sclerosis plaques: an immunohistochemical analysis
- (2014) Gillian Ingram et al. Acta Neuropathologica Communications
- Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects
- (2013) Otto Pedraza et al. Alzheimers & Dementia
- Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci
- (2013) Patrick Holton et al. ANNALS OF HUMAN GENETICS
- Extracellular chaperones prevent Aβ42-induced toxicity in rat brains
- (2013) Roberta Cascella et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Expression of the protein chaperone, clusterin, in spinal cord cells constitutively and following cellular stress, and upregulation by treatment with Hsp90 inhibitor
- (2013) Samantha Zinkie et al. CELL STRESS & CHAPERONES
- Plasma Clusterin Levels and the rs11136000 Genotype in Individuals with Mild Cognitive Impairment and Alzheimer’s Disease
- (2013) Gemma Mullan et al. Current Alzheimer Research
- Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
- (2013) J Chapuis et al. MOLECULAR PSYCHIATRY
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- The CLU Gene rs11136000 Variant is Significantly Associated with Alzheimer’s Disease in Caucasian and Asian Populations
- (2013) Guiyou Liu et al. NEUROMOLECULAR MEDICINE
- Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78
- (2013) Cun Wang et al. PLoS One
- SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians
- (2013) Akinori Miyashita et al. PLoS One
- Non-Secreted Clusterin Isoforms Are Translated in Rare Amounts from Distinct Human mRNA Variants and Do Not Affect Bax-Mediated Apoptosis or the NF-κB Signaling Pathway
- (2013) Hans Prochnow et al. PLoS One
- What are lipoproteins doing in the brain?
- (2013) Hong Wang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Clusterin in Alzheimer’s disease: a player in the biological behavior of amyloid-beta
- (2013) Xiang Li et al. Neuroscience Bulletin
- Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis
- (2013) Jonathon Telianidis et al. Frontiers in Aging Neuroscience
- What does complement do in Alzheimer’s disease? Old molecules with new insights
- (2013) Yong Shen et al. Translational Neurodegeneration
- Association of GWAS Top Hits With Late-onset Alzheimer Disease in Korean Population
- (2012) Sun Ju Chung et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Association Study of Clusterin Polymorphism rs11136000 With Late Onset Alzheimer’s Disease in Chinese Han Population
- (2012) Jian-Fang Ma et al. American Journal of Alzheimers Disease and Other Dementias
- Effect of Alzheimer’s Disease Risk Genes on Trajectories of Cognitive Function in the Cardiovascular Health Study
- (2012) Robert A. Sweet et al. AMERICAN JOURNAL OF PSYCHIATRY
- Multiple loci influencing hippocampal degeneration identified by genome scan
- (2012) Scott A. Melville et al. ANNALS OF NEUROLOGY
- Clusterin induces the secretion of TNF-α and the chemotactic migration of macrophages
- (2012) Young-Jun Shim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Alzheimer Risk Variant CLU and Brain Function During Aging
- (2012) Madhav Thambisetty et al. BIOLOGICAL PSYCHIATRY
- Clusterin inhibition using OGX-011 synergistically enhances antitumour activity of sorafenib in a human renal cell carcinoma model
- (2012) Y Kususda et al. BRITISH JOURNAL OF CANCER
- Secretory clusterin contributes to oxaliplatin resistance by activating Akt pathway in hepatocellular carcinoma
- (2012) Peng Xiu et al. CANCER SCIENCE
- Genetic polymorphisms of clusterin gene are associated with a decreased risk of Alzheimer’s disease
- (2012) Yen-Ling Lin et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Custirsen (OGX-011): a second-generation antisense inhibitor of clusterin in development for the treatment of prostate cancer
- (2012) Robert Zielinski et al. Future Oncology
- Small heat shock proteins in cancer therapy and prognosis
- (2012) Amina Zoubeidi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Knockdown of clusterin sensitizes pancreatic cancer cells to gemcitabine chemotherapy by ERK1/2 inactivation
- (2012) Yong Tang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid -Mediated Synaptic Loss
- (2012) S. A. Purro et al. JOURNAL OF NEUROSCIENCE
- Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk
- (2012) Karolien Bettens et al. Molecular Neurodegeneration
- Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway
- (2012) R Killick et al. MOLECULAR PSYCHIATRY
- Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory
- (2012) S. Barral et al. NEUROLOGY
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer
- (2012) N Li et al. ONCOGENE
- Genetics of Clusterin Isoform Expression and Alzheimer's Disease Risk
- (2012) I-Fang Ling et al. PLoS One
- Association study of susceptibility genes for late-onset Alzheimer’s disease in the Japanese population
- (2012) Tomoyuki Ohara et al. PSYCHIATRIC GENETICS
- Linkage Disequilibrium and Haplotype Analysis of the ATP7B Gene in Alzheimer's Disease
- (2012) Rosanna Squitti et al. REJUVENATION RESEARCH
- Association of the Alzheimer's GeneSORL1With Hippocampal Volume in Young, Healthy Adults
- (2011) Janita Bralten et al. AMERICAN JOURNAL OF PSYCHIATRY
- The Role of Clusterin, Complement Receptor 1, and Phosphatidylinositol Binding Clathrin Assembly Protein in Alzheimer Disease Risk and Cerebrospinal Fluid Biomarker Levels
- (2011) Brit-Maren M. Schjeide et al. ARCHIVES OF GENERAL PSYCHIATRY
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- (2011) C. Wang et al. CANCER RESEARCH
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- (2011) F. Lamoureux et al. CANCER RESEARCH
- Randomized Phase II Trial of Custirsen (OGX-011) in Combination with Docetaxel or Mitoxantrone as Second-line Therapy in Patients with Metastatic Castrate-Resistant Prostate Cancer Progressing after First-line Docetaxel: CUOG Trial P-06c
- (2011) F. Saad et al. CLINICAL CANCER RESEARCH
- Association of Clusterin Gene Polymorphisms with Late-Onset Alzheimer’s Disease
- (2011) Huiying Gu et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Neural hyperactivation in carriers of the Alzheimer's risk variant on the clusterin gene
- (2011) Thomas M. Lancaster et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
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- (2011) Hyoung-Oh Jun et al. EXPERIMENTAL AND MOLECULAR MEDICINE
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- (2011) Stephanie Materia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Stephanie Materia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Konstantin S. Leskov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Nayoung Kim et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2011) Young-Jun Shim et al. JOURNAL OF LEUKOCYTE BIOLOGY
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- (2011) Adam C Naj et al. NATURE GENETICS
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- (2011) Paul Hollingworth et al. NATURE GENETICS
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- (2011) Priyanka Narayan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2011) Lu Hua Chen et al. NEUROBIOLOGY OF AGING
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- (2011) L. D. Ward et al. NUCLEIC ACIDS RESEARCH
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- (2011) Madhav Thambisetty et al. PLoS One
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- (2011) Silvia Leoncini et al. REDOX REPORT
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- (2011) M Szymanski et al. Translational Psychiatry
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- (2009) Teri A. Manolio et al. NATURE
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- (2009) Jean-Charles Lambert et al. NATURE GENETICS
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- (2009) Denise Harold et al. NATURE GENETICS
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- (2009) John Hardy et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2009) N.-W. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) James T. Kapron et al. PROTEIN SCIENCE
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- (2008) Phullara B. Shelat et al. JOURNAL OF NEUROCHEMISTRY
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- (2007) O. Takase et al. KIDNEY INTERNATIONAL
- The BCL-2 protein family: opposing activities that mediate cell death
- (2007) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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