Linkage Disequilibrium and Haplotype Analysis of the ATP7B Gene in Alzheimer's Disease

Copper Hypothesis in the Missing Hereditability of Sporadic Alzheimer's Disease: ATP7B Gene as Potential Harbor of Rare Variants

(2018) Rosanna Squitti et al.   JOURNAL OF ALZHEIMERS DISEASE

Association of K832R and R952K SNPs of Wilson's Disease Gene with Alzheimer's Disease

(2018) Serena Bucossi et al.   JOURNAL OF ALZHEIMERS DISEASE

Diverse Functional Properties of Wilson Disease ATP7B Variants

(2012) Dominik Huster et al.   GASTROENTEROLOGY

Copper dysfunction in Alzheimer's disease: From meta-analysis of biochemical studies to new insight into genetics

(2012) Rosanna Squitti   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Copper toxicity in Alzheimer's disease: Cognitive loss from ingestion of inorganic copper

(2012) George J. Brewer   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Copper in Alzheimer disease: too much, too little, or misplaced?

(2011) Peter Faller   FREE RADICAL BIOLOGY AND MEDICINE

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease

(2011) Simon A. James et al.   FREE RADICAL BIOLOGY AND MEDICINE

Difference in Stability of the N-domain Underlies Distinct Intracellular Properties of the E1064A and H1069Q Mutants of Copper-transporting ATPase ATP7B

(2011) Oleg Y. Dmitriev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of hemochromatosis and transferrin gene mutations on iron dyshomeostasis, liver dysfunction and on the risk of Alzheimer's disease

(2011) Federica Giambattistelli et al.   NEUROBIOLOGY OF AGING

Functional analysis of mutations in the ATP loop of the Wilson disease copper transporter, ATP7B

(2010) Leiah M. Luoma et al.   HUMAN MUTATION

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Neurologic Wilson's disease

(2009) Matthew T. Lorincz   Annals of the New York Academy of Sciences

Agents Complexing Copper as a Therapeutic Strategy for the Treatment of Alzheimers Disease

(2009) Rosanna Squitti et al.   Current Alzheimer Research

Interactions between Copper-binding Sites Determine the Redox Status and Conformation of the Regulatory N-terminal Domain of ATP7B

(2009) Erik S. LeShane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc and tetrathiomolybdate for the treatment of Wilson’s disease and the potential efficacy of anticopper therapy in a wide variety of diseases

(2009) George J. Brewer   Metallomics

Longitudinal prognostic value of serum "free" copper in patients with Alzheimer disease

(2009) R. Squitti et al.   NEUROLOGY

PGA: power calculator for case-control genetic association analyses

(2008) Idan Menashe et al.   BMC GENETICS

Stability and ATP Binding of the Nucleotide-binding Domain of the Wilson Disease Protein: Effect of the Common H1069Q Mutation

(2008) Agustina Rodriguez-Granillo et al.   JOURNAL OF MOLECULAR BIOLOGY

Therapeutics for Alzheimer’s disease based on the metal hypothesis

(2008) Ashley I. Bush et al.   Neurotherapeutics