Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 43, Pages 26043-26050
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-09-16
DOI
10.1074/jbc.m115.679043
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response
- (2015) Li Zhong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway
- (2015) Caroline S. Casey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 sustains microglial expansion during aging and response to demyelination
- (2015) Pietro Luigi Poliani et al. JOURNAL OF CLINICAL INVESTIGATION
- TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
- (2015) Taylor R. Jay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke
- (2015) M. Kawabori et al. JOURNAL OF NEUROSCIENCE
- TREM2 is associated with increased risk for Alzheimer’s disease in African Americans
- (2015) Sheng Chih Jin et al. Molecular Neurodegeneration
- More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk
- (2015) Samantha L. Rosenthal et al. NEUROBIOLOGY OF AGING
- TREM2 R47H variant and risk of essential tremor: A cross-sectional international multicenter study
- (2015) Sara Ortega-Cubero et al. PARKINSONISM & RELATED DISORDERS
- R47H Variant ofTREM2Associated With Alzheimer Disease in a Large Late-Onset Family
- (2015) Olena Korvatska et al. JAMA Neurology
- Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk
- (2014) Leon M Tai et al. Molecular Neurodegeneration
- Homozygous TREM2 mutation in a family with atypical frontotemporal dementia
- (2014) Isabelle Le Ber et al. NEUROBIOLOGY OF AGING
- ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?
- (2014) Takahisa Kanekiyo et al. NEURON
- Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease
- (2014) Teng Jiang et al. NEUROPSYCHOPHARMACOLOGY
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis
- (2014) Janet Cady et al. JAMA Neurology
- TREM2 and the neuroimmunology of Alzheimer's disease
- (2013) Suzanne E. Hickman et al. BIOCHEMICAL PHARMACOLOGY
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease
- (2013) Sruti Rayaprolu et al. Molecular Neurodegeneration
- Blood–brain-barriers in aging and in Alzheimer’s disease
- (2013) Fernanda Marques et al. Molecular Neurodegeneration
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease
- (2013) Margarita Giraldo et al. NEUROBIOLOGY OF AGING
- TREM2 is associated with the risk of Alzheimer's disease in Spanish population
- (2013) Bruno A. Benitez et al. NEUROBIOLOGY OF AGING
- Heterozygous TREM2 mutations in frontotemporal dementia
- (2013) Barbara Borroni et al. NEUROBIOLOGY OF AGING
- Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
- (2013) Elise Cuyvers et al. NEUROBIOLOGY OF AGING
- ApoE influences amyloid- (A ) clearance despite minimal apoE/A association in physiological conditions
- (2013) P. B. Verghese et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement
- (2013) Rita João Guerreiro et al. JAMA Neurology
- LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid-
- (2012) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Variant TREM2 as Risk Factor for Alzheimer's Disease
- (2012) Harald Neumann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
- (2011) Hiroaki Ito et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid- Uptake
- (2011) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Excitotoxicity of TNFα derived from KA activated microglia on hippocampal neurons in vitro and in vivo
- (2010) Wei Zhu et al. JOURNAL OF NEUROCHEMISTRY
- TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria
- (2009) Elsa-Noah N'Diaye et al. JOURNAL OF CELL BIOLOGY
- A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
- (2009) Christine L. Hsieh et al. JOURNAL OF NEUROCHEMISTRY
- Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
- (2009) Guojun Bu NATURE REVIEWS NEUROSCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started