Pseudoexfoliation and Alzheimer’s associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression

Reduced Insulin/IGF-1 Signaling Restores the Dynamic Properties of Key Stress Granule Proteins during Aging

(2017) Marie C. Lechler et al.   Cell Reports

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

(2016) Julien Chapuis et al.   ACTA NEUROPATHOLOGICA

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

(2016) P Dourlen et al.   MOLECULAR PSYCHIATRY

NEDD4-mediated HSF1 degradation underlies α-synucleinopathy

(2015) Eunhee Kim et al.   HUMAN MOLECULAR GENETICS

CD33 modulates TREM2: convergence of Alzheimer loci

(2015) Gail Chan et al.   NATURE NEUROSCIENCE

An artificial HSE promoter for efficient and selective detection of heat shock pathway activity

(2014) Viktoria Ortner et al.   CELL STRESS & CHAPERONES

Role of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

(2014) Biswajit Padhy et al.   EXPERIMENTAL EYE RESEARCH

HSF1 Protects Neurons through a Novel Trimerization- and HSP-Independent Mechanism

(2014) P. Verma et al.   JOURNAL OF NEUROSCIENCE

The Systemic Amyloid Precursor Transthyretin (TTR) Behaves as a Neuronal Stress Protein Regulated by HSF1 in SH-SY5Y Human Neuroblastoma Cells and APP23 Alzheimer's Disease Model Mice

(2014) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease

(2014) Yuan Zhou et al.   PLoS One

Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease

(2013) Yu-Qing Jiang et al.   BRAIN RESEARCH

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice

(2013) Christoph Köhler et al.   NEUROBIOLOGY OF AGING

mTOR: at the crossroads of aging, chaperones, and Alzheimer's disease

(2012) Gunnar K. Gouras   JOURNAL OF NEUROCHEMISTRY

Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains

(2012) Celeste M. Karch et al.   PLoS One

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

(2011) Daniel W. Neef et al.   NATURE REVIEWS DRUG DISCOVERY

Association of the clusterin gene polymorphisms with type 2 diabetes mellitus

(2010) Makoto Daimon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Advances and Challenges in Basic and Translational Research on Clusterin

(2009) I. P. Trougakos et al.   CANCER RESEARCH

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS