Exosomes in Inflammation and Inflammatory Disease

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

(2018) Maitrayee Sardar Sinha et al.   ACTA NEUROPATHOLOGICA

Lymphatic exosomes promote dendritic cell migration along guidance cues

(2018) Markus Brown et al.   JOURNAL OF CELL BIOLOGY

Characterization of rat primary trigeminal satellite glial cells and associated extracellular vesicles under normal and inflammatory conditions

(2018) Hye Sook Han Vinterhøj et al.   Journal of Proteomics

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

(2018) Tian Fang et al.   Nature Communications

Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection

(2018) Patricia Jeannin et al.   Scientific Reports

Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis

(2018) Stella Cosenza et al.   Theranostics

Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris

(2018) Sarah Caruso et al.   Frontiers in Immunology

Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells

(2017) Sang Bum Kim et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin Conjugation Probed by Inflammation in Myeloid-Derived Suppressor Cell Extracellular Vesicles

(2017) Katherine R. Adams et al.   JOURNAL OF PROTEOME RESEARCH

Exosome-Mediated miR-155 Transfer from Smooth Muscle Cells to Endothelial Cells Induces Endothelial Injury and Promotes Atherosclerosis

(2017) Bin Zheng et al.   MOLECULAR THERAPY

Exosomes: Therapy delivery tools and biomarkers of diseases

(2017) Lucio Barile et al.   PHARMACOLOGY & THERAPEUTICS

Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation

(2017) Diana Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation

(2017) Yvonne Couch et al.   STROKE

Exosomes, DAMPs and miRNA: Features of Stress Physiology and Immune Homeostasis

(2017) Monika Fleshner et al.   TRENDS IN IMMUNOLOGY

Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90

(2017) Guohua Zhang et al.   Nature Communications

Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis

(2017) Stella Cosenza et al.   Scientific Reports

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix

(2017) Yafei Wang et al.   Stem Cell Research & Therapy

Salivary exosomal PSMA7: a promising biomarker of inflammatory bowel disease

(2017) Xiaowen Zheng et al.   Protein & Cell

Extracellular Vesicles Secreted by Atherogenic Macrophages Transfer MicroRNA to Inhibit Cell Migration

(2017) My-Anh Nguyen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes

(2017) Marta Garcia-Contreras et al.   Scientific Reports

Exosomal microRNA signatures in multiple sclerosis reflect disease status

(2017) Saeideh Ebrahimkhani et al.   Scientific Reports

Noncanonical WNT-5B signaling induces inflammatory responses in human lung fibroblasts

(2016) Eline M. van Dijk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Wnt5b-associated exosomes promote cancer cell migration and proliferation

(2016) Takeshi Harada et al.   CANCER SCIENCE

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Exosomes Released from Cells Infected with Crohnʼs Disease–associated Adherent-Invasive Escherichia coli Activate Host Innate Immune Responses and Enhance Bacterial Intracellular Replication

(2016) Jessica Carrière et al.   INFLAMMATORY BOWEL DISEASES

Luminal Extracellular Vesicles (EVs) in Inflammatory Bowel Disease (IBD) Exhibit Proinflammatory Effects on Epithelial Cells and Macrophages

(2016) Shuji Mitsuhashi et al.   INFLAMMATORY BOWEL DISEASES

Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosisviamembrane TNF-α mediated NF-κB pathway

(2016) Wei Gao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation

(2016) Cecilia Lässer et al.   Journal of Translational Medicine

Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth

(2016) M.A. Lopez-Verrilli et al.   NEUROSCIENCE

Proteomic profiling of dextran sulfate sodium induced acute ulcerative colitis mice serum exosomes and their immunomodulatory impact on macrophages

(2016) Wing-Yan Wong et al.   PROTEOMICS

Extracellular miRNA: A Collision of Two Paradigms

(2016) Andrey Turchinovich et al.   TRENDS IN BIOCHEMICAL SCIENCES

Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression

(2016) Lijun Wu et al.   TUMOR BIOLOGY

Exosomes Mediate LTB4 Release during Neutrophil Chemotaxis

(2016) Ritankar Majumdar et al.   PLOS BIOLOGY

Urinary Exosomal miRNA Signature in Type II Diabetic Nephropathy Patients

(2016) Denis Delić et al.   PLoS One

Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets

(2016) Laurent Muller et al.   Scientific Reports

Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

(2016) Kanna Nagaishi et al.   Scientific Reports

Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

(2015) Kobina Essandoh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study

(2015) MikoŁaj P. Zaborowski et al.   BIOSCIENCE

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies

(2015) Anne Stuendl et al.   BRAIN

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS

(2015) Fatemeh Momen-Heravi et al.   Scientific Reports

Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers

(2015) Giovanni Lugli et al.   PLoS One

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

EVpedia: a community web portal for extracellular vesicles research

(2014) D.-K. Kim et al.   BIOINFORMATICS

Acceleration of α-Synuclein Aggregation by Exosomes

(2014) Marie Grey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells

(2014) Dhafer Mrizak et al.   JNCI-Journal of the National Cancer Institute

Functional significance of macrophage-derived exosomes in inflammation and pain

(2014) Marguerite K. McDonald et al.   PAIN

Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease

(2014) Davide Povero et al.   PLoS One

Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes

(2014) Tomohiro Kato et al.   ARTHRITIS RESEARCH & THERAPY

Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB

(2014) Amy Chow et al.   Scientific Reports

The emerging role of miRNAs in inflammatory bowel disease: a review

(2014) Christopher G. Chapman et al.   Therapeutic Advances in Gastroenterology

Intercellular Transport of MicroRNAs

(2013) Reinier A. Boon et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

(2013) Niko P. Bretz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Essential nontranslational functions of tRNA synthetases

(2013) Min Guo et al.   Nature Chemical Biology

Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy

(2013) Federica Barutta et al.   PLoS One

Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes

(2013) Takeshi Katsuda et al.   Scientific Reports

Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS

(2012) Michelle Demory Beckler et al.   MOLECULAR & CELLULAR PROTEOMICS

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

miRandola: Extracellular Circulating MicroRNAs Database

(2012) Francesco Russo et al.   PLoS One

Activated Human T Cells Secrete Exosomes That Participate in IL-2 Mediated Immune Response Signaling

(2012) Jessica Wahlgren et al.   PLoS One

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production

(2011) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes

(2010) O. Ashiru et al.   CANCER RESEARCH

Microparticles From Human Atherosclerotic Plaques Promote Endothelial ICAM-1–Dependent Monocyte Adhesion and Transendothelial Migration

(2010) Pierre-Emmanuel Rautou et al.   CIRCULATION RESEARCH

Exosomal Hsp70 Induces a Pro-Inflammatory Response to Foreign Particles Including Mycobacteria

(2010) Paras K. Anand et al.   PLoS One

Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis

(2010) K. R. Qazi et al.   THORAX

MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome

(2009) Q. Zhou et al.   GUT