Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis

Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles

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Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1β-Primed Mesenchymal Stem Cells Against Sepsis

(2017) Yuxian Song et al.   STEM CELLS

Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

(2017) Yu Zhu et al.   Stem Cell Research & Therapy

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix

(2017) Yafei Wang et al.   Stem Cell Research & Therapy

Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model

(2017) Shi-Cong Tao et al.   Theranostics

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis

(2016) Harini Raghu et al.   ANNALS OF THE RHEUMATIC DISEASES

Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis

(2016) Alexandre T.J. Maria et al.   JOURNAL OF AUTOIMMUNITY

Alarmin S100A9 Induces Proinflammatory and Catabolic Effects Predominantly in the M1 Macrophages of Human Osteoarthritic Synovium

(2016) M. H. van den Bosch et al.   JOURNAL OF RHEUMATOLOGY

Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial

(2016) Yves-Marie Pers et al.   Stem Cells Translational Medicine

Utility of a Mouse Model of Osteoarthritis to Demonstrate Cartilage Protection by IFNγ-Primed Equine Mesenchymal Stem Cells

(2016) Marie Maumus et al.   Frontiers in Immunology

Therapeutic application of mesenchymal stem cells in osteoarthritis

(2015) Maxime Ruiz et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Exosomes in Mesenchymal Stem Cells, a New Therapeutic Strategy for Cardiovascular Diseases?

(2015) Lina Huang et al.   International Journal of Biological Sciences

Survival and Biodistribution of Xenogenic Adipose Mesenchymal Stem Cells Is Not Affected by the Degree of Inflammation in Arthritis

(2015) Karine Toupet et al.   PLoS One

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

(2015) Sarah E. Headland et al.   Science Translational Medicine

Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation

(2015) Patricia Luz-Crawford et al.   STEM CELLS

Mesenchymal Stem Cells Suppress Fibroblast Proliferation and Reduce Skin Fibrosis Through a TGF-β3-Dependent Activation

(2015) Yan Wu et al.   International Journal of Lower Extremity Wounds

Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels

(2014) R.F. Schelbergen et al.   OSTEOARTHRITIS AND CARTILAGE

The Burden of Musculoskeletal Conditions

(2014) Clémence Palazzo et al.   PLoS One

Adipose-Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E2

(2013) Cristina Manferdini et al.   ARTHRITIS AND RHEUMATISM

Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis

(2013) Marie Maumus et al.   Stem Cell Research

Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model

(2013) Giovanna Desando et al.   ARTHRITIS RESEARCH & THERAPY

Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis

(2012) Menno ter Huurne et al.   ARTHRITIS AND RHEUMATISM

The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis

(2012) Mária Pásztói et al.   IMMUNOLOGY LETTERS

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity

(2012) Alessandra Lo Cicero et al.   MATRIX BIOLOGY

Multimodal imaging demonstrates concomitant changes in bone and cartilage after destabilisation of the medial meniscus and increased joint laxity

(2010) J.P. Moodie et al.   OSTEOARTHRITIS AND CARTILAGE

Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

(2010) Julian Maggini et al.   PLoS One

Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models

(2009) Nicole R. Bianco et al.   ARTHRITIS AND RHEUMATISM

TGF-β3: A potential biological therapy for enhancing chondrogenesis

(2009) Quen Oak Tang et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts

(2009) Mária Pásztói et al.   ARTHRITIS RESEARCH & THERAPY

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols