Active Wnt proteins are secreted on exosomes

Mechanism of Evenness Interrupted (Evi)-Exosome Release at Synaptic Boutons

(2012) Kate Koles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis

(2011) Sanyukta Rana et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SNARE Proteins Are Required for Macroautophagy

(2011) Usha Nair et al.   CELL

SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless

(2011) Peng Zhang et al.   CELL RESEARCH

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling

(2011) Lenka Doubravska et al.   CELLULAR SIGNALLING

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Porcupine-mediated lipidation is required for Wnt recognition by Wls

(2011) Patrick Herr et al.   DEVELOPMENTAL BIOLOGY

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

(2011) Iris Augustin et al.   EMBO Molecular Medicine

p24 proteins are required for secretion of Wnt ligands

(2011) Tina Buechling et al.   EMBO REPORTS

A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion

(2011) Fillip Port et al.   EMBO REPORTS

Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation

(2011) Kévin Carayon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

(2011) Martin Harterink et al.   NATURE CELL BIOLOGY

Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

(2011) K. A. Mulligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells

(2011) Tim Koppen et al.   PROTEOMICS

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein

(2010) Keiichi Tamai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

(2010) Vincent F. Taelman et al.   CELL

The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor

(2010) T. Vaccari et al.   DEVELOPMENT

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

(2010) G. S. Coombs et al.   JOURNAL OF CELL SCIENCE

E-RNAi: a web application for the multi-species design of RNAi reagents—2010 update

(2010) Thomas Horn et al.   NUCLEIC ACIDS RESEARCH

Human tumor virus utilizes exosomes for intercellular communication

(2010) D. G. Meckes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt Trafficking: New Insights into Wnt Maturation, Secretion and Spreading

(2010) Fillip Port et al.   TRAFFIC

Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless

(2009) Ceren Korkut et al.   CELL

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins

(2009) J. A. Sobota et al.   JOURNAL OF CELL SCIENCE

GM1 structure determines SV40-induced membrane invagination and infection

(2009) Helge Ewers et al.   NATURE CELL BIOLOGY

Mammalian Wnt3a is Released on Lipoprotein Particles

(2009) Sylvia Neumann et al.   TRAFFIC

Regulation of Wnt protein secretion and its role in gradient formation

(2008) Kerstin Bartscherer et al.   EMBO REPORTS

In vivo role of lipid adducts on Wingless

(2008) X. Franch-Marro et al.   JOURNAL OF CELL SCIENCE

Wingless secretion promotes and requires retromer-dependent cycling of Wntless

(2008) Fillip Port et al.   NATURE CELL BIOLOGY

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

(2008) Xavier Franch-Marro et al.   NATURE CELL BIOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Midbody Targeting of the ESCRT Machinery by a Noncanonical Coiled Coil in CEP55

(2008) H. H. Lee et al.   SCIENCE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Depalmitoylation of Ykt6 Prevents its Entry into the Multivesicular Body Pathway

(2008) Christoph T. A. Meiringer et al.   TRAFFIC

Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies

(2008) Véronique Pons et al.   PLOS BIOLOGY

The Retromer Complex Influences Wnt Secretion by Recycling Wntless from Endosomes to the Trans-Golgi Network

(2007) Tatyana Y. Belenkaya et al.   DEVELOPMENTAL CELL

Wnt Signaling Requires Retromer-Dependent Recycling of MIG-14/Wntless in Wnt-Producing Cells

(2007) Pei-Tzu Yang et al.   DEVELOPMENTAL CELL

C. elegans AP-2 and Retromer Control Wnt Signaling by Regulating MIG-14/Wntless

(2007) Chun-Liang Pan et al.   DEVELOPMENTAL CELL