Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease
Authors
Keywords
-
Journal
Nature Reviews Neurology
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-03-20
DOI
10.1038/s41582-019-0157-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis
- (2018) Jade-Emmanuelle Deshaies et al. BRAIN
- Phase Transitions in the Assembly and Function of Human miRISC
- (2018) Jessica Sheu-Gruttadauria et al. CELL
- Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
- (2018) Mario Hofweber et al. CELL
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
- (2018) Ke Zhang et al. CELL
- Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
- (2018) Lin Guo et al. CELL
- FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
- (2018) Seema Qamar et al. CELL
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- Acetylation Disfavors Tau Phase Separation
- (2018) Josephine Ferreon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
- (2018) Thuy P. Dao et al. MOLECULAR CELL
- Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
- (2018) Veronica H. Ryan et al. MOLECULAR CELL
- Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
- (2018) Yong-Jie Zhang et al. NATURE MEDICINE
- Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation
- (2018) Elizabeth L. Guenther et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration
- (2018) Baskar Bakthavachalu et al. NEURON
- Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
- (2018) Aude Nicolas et al. NEURON
- RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome
- (2018) Briana Van Treeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA buffers the phase separation behavior of prion-like RNA binding proteins
- (2018) Shovamayee Maharana et al. SCIENCE
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation
- (2018) Elizabeth L. Guenther et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A New Lens for RNA Localization: Liquid-Liquid Phase Separation
- (2018) Erin M. Langdon et al. Annual Review of Microbiology
- Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies
- (2018) Briana Van Treeck et al. CELL
- The molecular language of membraneless organelles
- (2018) Edward Gomes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
- (2018) Leeanne McGurk et al. MOLECULAR CELL
- Liquid and Hydrogel Phases of PrPC Linked to Conformation Shifts and Triggered by Alzheimer’s Amyloid-β Oligomers
- (2018) Mikhail A. Kostylev et al. MOLECULAR CELL
- TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle
- (2018) Thomas O. Vogler et al. NATURE
- ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
- (2018) Jone López-Erauskin et al. NEURON
- The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules
- (2017) Anthony Khong et al. MOLECULAR CELL
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- Phase separation drives heterochromatin domain formation
- (2017) Amy R. Strom et al. NATURE
- Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
- (2017) Lindsay A. Becker et al. NATURE
- RNA phase transitions in repeat expansion disorders
- (2017) Ankur Jain et al. NATURE
- Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
- (2017) Adam G. Larson et al. NATURE
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
- (2017) Fatima Gasset-Rosa et al. NEURON
- TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
- (2017) Ian R. Mackenzie et al. NEURON
- Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases
- (2017) Hong Joo Kim et al. NEURON
- Toxic PRnpoly-dipeptides encoded by theC9orf72repeat expansion block nuclear import and export
- (2017) Kevin Y. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATP as a biological hydrotrope
- (2017) Avinash Patel et al. SCIENCE
- Liquid phase condensation in cell physiology and disease
- (2017) Yongdae Shin et al. SCIENCE
- Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis
- (2017) Bradley N. Smith et al. Science Translational Medicine
- Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
- (2017) Susmitha Ambadipudi et al. Nature Communications
- Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
- (2017) Amayra Hernández-Vega et al. Cell Reports
- Genetics of Amyotrophic Lateral Sclerosis
- (2017) Mehdi Ghasemi et al. Cold Spring Harbor Perspectives in Medicine
- RNA stores tau reversibly in complex coacervates
- (2017) Xuemei Zhang et al. PLOS BIOLOGY
- Spinocerebellar Ataxia Type 2: Clinicogenetic Aspects, Mechanistic Insights, and Management Approaches
- (2017) Luis C. Velázquez-Pérez et al. Frontiers in Neurology
- Stress granules at the intersection of autophagy and ALS
- (2016) Zachary Monahan et al. BRAIN RESEARCH
- ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure
- (2016) Saumya Jain et al. CELL
- C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
- (2016) Kyung-Ha Lee et al. CELL
- Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
- (2016) Yi Lin et al. CELL
- Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
- (2016) Kohsuke Kanekura et al. HUMAN MOLECULAR GENETICS
- Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies
- (2016) Dipen Rajgor et al. MOLECULAR BIOLOGY OF THE CELL
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- Whole-exome sequencing identifies a missense mutation in hnRNPA1 in a family with flail arm ALS
- (2016) Qing Liu et al. NEUROLOGY
- TDP-43/FUS in motor neuron disease: Complexity and challenges
- (2016) Erika N. Guerrero et al. PROGRESS IN NEUROBIOLOGY
- The Cajal body and the nucleolus: “In a relationship” or “It's complicated”?
- (2016) Laura Trinkle-Mulcahy et al. RNA Biology
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Principles and Properties of Stress Granules
- (2016) David S.W. Protter et al. TRENDS IN CELL BIOLOGY
- Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
- (2015) Martin H. Schludi et al. ACTA NEUROPATHOLOGICA
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Phase Transition of Spindle-Associated Protein Regulate Spindle Apparatus Assembly
- (2015) Hao Jiang et al. CELL
- Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
- (2015) Yuan Lin et al. MOLECULAR CELL
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
- (2015) Mercedes Prudencio et al. NATURE NEUROSCIENCE
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
- Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
- (2015) Ana Jovičić et al. NATURE NEUROSCIENCE
- Polymer physics of intracellular phase transitions
- (2015) Clifford P. Brangwynne et al. Nature Physics
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- RAN Translation in Huntington Disease
- (2015) Monica Bañez-Coronel et al. NEURON
- Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis
- (2015) Sami J. Barmada Neurotherapeutics
- Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy
- (2015) Agnieszka Wojtkowiak-Szlachcic et al. NUCLEIC ACIDS RESEARCH
- TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
- (2015) J. P. Ling et al. SCIENCE
- Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
- (2015) Matthias Altmeyer et al. Nature Communications
- GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function
- (2015) Alondra Schweizer Burguete et al. eLife
- Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
- (2015) Hermann Broder Schmidt et al. eLife
- Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy
- (2015) M. Carolina Gallego-Iradi et al. PLoS One
- TDP-43 regulatesβ-adducin(Add2) transcript stability
- (2015) Luisa Costessi et al. RNA Biology
- Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine
- (2014) David J. Irwin et al. ACTA NEUROPATHOLOGICA
- A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement
- (2014) Sylvie Bannwarth et al. BRAIN
- Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis
- (2014) Hannah M. Kaneb et al. HUMAN MOLECULAR GENETICS
- A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G)
- (2014) Natássia M. Vieira et al. HUMAN MOLECULAR GENETICS
- Poly(ADP-ribose): An organizer of cellular architecture
- (2014) Anthony K.L. Leung JOURNAL OF CELL BIOLOGY
- C9orf72 nucleotide repeat structures initiate molecular cascades of disease
- (2014) Aaron R. Haeusler et al. NATURE
- Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
- (2014) Janel O Johnson et al. NATURE NEUROSCIENCE
- Autophagy meets fused in sarcoma-positive stress granules
- (2014) Soledad Matus et al. NEUROBIOLOGY OF AGING
- Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
- (2014) Xinmei Wen et al. NEURON
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS
- (2014) Bradley N. Smith et al. NEURON
- mRNP granules
- (2014) J Ross Buchan RNA Biology
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
- (2014) S. Mizielinska et al. SCIENCE
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
- (2014) I. Kwon et al. SCIENCE
- Nucleoli and Stress Granules: Connecting Distant Relatives
- (2014) Hicham Mahboubi et al. TRAFFIC
- Phase transitions of multivalent proteins can promote clustering of membrane receptors
- (2014) Sudeep Banjade et al. eLife
- Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations
- (2013) Ian R. Mackenzie et al. ACTA NEUROPATHOLOGICA
- Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
- (2013) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum
- (2013) Matthew Thomas et al. BRAIN
- Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
- (2013) J. Ross Buchan et al. CELL
- Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders
- (2013) Mani Ramaswami et al. CELL
- Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis
- (2013) Tomohiko Ishihara et al. HUMAN MOLECULAR GENETICS
- Compromised paraspeckle formation as a pathogenic factor in FUSopathies
- (2013) Tatyana A. Shelkovnikova et al. HUMAN MOLECULAR GENETICS
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- CGG Repeat-Associated Translation Mediates Neurodegeneration in Fragile X Tremor Ataxia Syndrome
- (2013) Peter K. Todd et al. NEURON
- RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
- (2013) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration
- (2013) Z. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
- (2013) E. S. Arnold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
- (2013) Youn-Bok Lee et al. Cell Reports
- ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
- (2013) Yueqin Zhou et al. PLoS Genetics
- Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72
- (2013) David MA Mann et al. Acta Neuropathologica Communications
- The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
- (2012) Oliver D. King et al. BRAIN RESEARCH
- Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
- (2012) Eric T. Wang et al. CELL
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Nuclear bodies: multifunctional companions of the genome
- (2012) Miroslav Dundr CURRENT OPINION IN CELL BIOLOGY
- FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2
- (2012) J. C. Schwartz et al. GENES & DEVELOPMENT
- Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
- (2012) Julien Couthouis et al. HUMAN MOLECULAR GENETICS
- TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells
- (2012) Claudia Colombrita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
- (2012) Chi-Hong Wu et al. NATURE
- Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
- (2012) Clotilde Lagier-Tourenne et al. NATURE NEUROSCIENCE
- TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
- (2012) Y. Kawahara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation
- (2012) C. J. Decker et al. Cold Spring Harbor Perspectives in Biology
- C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
- (2012) Pietro Fratta et al. Scientific Reports
- FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA
- (2012) Tomohiro Yamazaki et al. Cell Reports
- Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins
- (2012) Stephanie C. Huelga et al. Cell Reports
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
- (2011) C. P. Brangwynne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A yeast functional screen predicts new candidate ALS disease genes
- (2011) J. Couthouis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
- (2011) Zhihui Sun et al. PLOS BIOLOGY
- ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
- (2010) Dorothee Dormann et al. EMBO JOURNAL
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- TDP43-Positive Intraneuronal Inclusions in a Patient with Motor Neuron Disease and Parkinson’s Disease
- (2010) Jean-Baptiste Chanson et al. Neurodegenerative Diseases
- Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS
- (2010) Janel O. Johnson et al. NEURON
- Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
- (2010) Liqun Liu-Yesucevitz et al. PLoS One
- Non-ATG-initiated translation directed by microsatellite expansions
- (2010) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transactive Response DNA-Binding Protein 43 Burden in Familial Alzheimer Disease and Down Syndrome
- (2009) Carol F. Lippa et al. ARCHIVES OF NEUROLOGY
- A new subtype of frontotemporal lobar degeneration with FUS pathology
- (2009) M. Neumann et al. BRAIN
- Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS)
- (2009) Kathryn Volkening et al. BRAIN RESEARCH
- Amyotrophic Lateral Sclerosis-linked Mutant SOD1 Sequesters Hu Antigen R (HuR) and TIA-1-related Protein (TIAR)
- (2009) Liang Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
- (2009) Brian S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
- (2009) Brian D. Freibaum et al. JOURNAL OF PROTEOME RESEARCH
- Sarcoplasmic redistribution of nuclear TDP-43 in inclusion body myositis
- (2009) Mohammad Salajegheh et al. MUSCLE & NERVE
- Molecular mechanisms for protein-encoded inheritance
- (2009) Jed J W Wiltzius et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation
- (2008) Matthew J. Winton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
- (2008) I.-Fan Wang et al. JOURNAL OF NEUROCHEMISTRY
- TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia
- (2008) C C Weihl et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Colocalization of Transactivation-Responsive DNA-Binding Protein 43 and Huntingtin in Inclusions of Huntington Disease
- (2008) Claudia Schwab et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Concomitant TAR-DNA-Binding Protein 43 Pathology Is Present in Alzheimer Disease and Corticobasal Degeneration but Not in Other Tauopathies
- (2008) Kunihiro Uryu et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Mutations in mRNA export mediator GLE1 result in a fetal motoneuron disease
- (2008) Heidi O Nousiainen et al. NATURE GENETICS
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Stress granules: the Tao of RNA triage
- (2008) Paul Anderson et al. TRENDS IN BIOCHEMICAL SCIENCES
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search