Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers

Published 2016 View Full Article

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Title
Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
Authors
Keywords
labile, amyloid-like polymers, C9orf72, toxic PRn and GRn poly-dipeptides, low complexity sequence polymers, cellular puncta not invested by surrounding membranes, 1,6-hexanediol, intermediate filaments
Journal
CELL
Volume 167, Issue 3, Pages 789-802.e12
Publisher
Elsevier BV
Online
2016-10-21
DOI
10.1016/j.cell.2016.10.003

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