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Title
Cholangiocyte pathobiology
Authors
Keywords
-
Journal
Nature Reviews Gastroenterology & Hepatology
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-03-08
DOI
10.1038/s41575-019-0125-y
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- (2018) Claudio Pinto et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pathophysiologic implications of innate immunity and autoinflammation in the biliary epithelium
- (2018) Mario Strazzabosco et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations
- (2018) Emma R. Andersson et al. GASTROENTEROLOGY
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- (2018) Dipen Vyas et al. HEPATOLOGY
- β-Catenin and interleukin-1β-dependent chemokine (C-X-C motif) ligand 10 production drives progression of disease in a mouse model of congenital hepatic fibrosis
- (2018) Eleanna Kaffe et al. HEPATOLOGY
- MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation
- (2018) Oihane Erice et al. HEPATOLOGY
- MAIT cells are chronically activated in patients with autoimmune liver disease and promote profibrogenic hepatic stellate cell activation
- (2018) Katrin Böttcher et al. HEPATOLOGY
- The immunobiology of mucosal-associated invariant T cell (MAIT) function in primary biliary cholangitis: Regulation by cholic acid-induced Interleukin-7
- (2018) Xiang Jiang et al. JOURNAL OF AUTOIMMUNITY
- Development of the liver: Insights into organ and tissue morphogenesis
- (2018) Elke A. Ober et al. JOURNAL OF HEPATOLOGY
- Ductular reaction in liver diseases: pathological mechanisms and translational significances
- (2018) Keisaku Sato et al. HEPATOLOGY
- Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases
- (2018) Diletta Overi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation
- (2018) Johanna R. Schaub et al. NATURE
- Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
- (2018) Francesca Zanconato et al. NATURE MEDICINE
- Cholangiocytes and the environment in primary sclerosing cholangitis: where is the link?
- (2017) Steven P O’Hara et al. GUT
- Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
- (2017) Rudi Alberts et al. GUT
- Hepatostat: Liver regeneration and normal liver tissue maintenance
- (2017) George K. Michalopoulos HEPATOLOGY
- Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/− ) mice
- (2017) Anja Moncsek et al. HEPATOLOGY
- Primary sclerosing cholangitis – a comprehensive review
- (2017) Tom H. Karlsen et al. JOURNAL OF HEPATOLOGY
- SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma
- (2017) Maite Merino-Azpitarte et al. JOURNAL OF HEPATOLOGY
- Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
- (2017) Mette Vesterhus et al. JOURNAL OF HEPATOLOGY
- Structural and functional integrity of human serum albumin: Analytical approaches and clinical relevance in patients with liver cirrhosis
- (2017) Marina Naldi et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis
- (2017) Lorena Loarca et al. LABORATORY INVESTIGATION
- Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
- (2017) Alexander Raven et al. NATURE
- Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
- (2017) Fotios Sampaziotis et al. Nature Protocols
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Notch signaling and progenitor/ductular reaction in steatohepatitis
- (2017) Carola M. Morell et al. PLoS One
- The Microbiome in Primary Sclerosing Cholangitis: Current Evidence and Potential Concepts
- (2017) Johannes Hov et al. SEMINARS IN LIVER DISEASE
- Regenerative Medicine and the Biliary Tree
- (2017) Thiago De Assuncao et al. SEMINARS IN LIVER DISEASE
- Update on the Mechanisms of Liver Regeneration
- (2017) Morgan Preziosi et al. SEMINARS IN LIVER DISEASE
- Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications
- (2017) Eduardo Cervantes-Alvarez et al. Organogenesis
- Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes
- (2017) Bin Li et al. Stem Cell Reports
- Laminin 411 and 511 promote the cholangiocyte differentiation of human induced pluripotent stem cells
- (2016) Kazuo Takayama et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Galectin-3 regulates inflammasome activation in cholestatic liver injury
- (2016) Jijing Tian et al. FASEB JOURNAL
- Stem/progenitor cells in liver regeneration
- (2016) Tohru Itoh HEPATOLOGY
- Macrophage recruitment by fibrocystin-defective biliary epithelial cells promotes portal fibrosis in congenital hepatic fibrosis
- (2016) Luigi Locatelli et al. HEPATOLOGY
- Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1
- (2016) Hannah C. Jeffery et al. JOURNAL OF HEPATOLOGY
- Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis
- (2016) Serge J. Zweers et al. LIVER INTERNATIONAL
- Stem cells versus plasticity in liver and pancreas regeneration
- (2016) Janel L. Kopp et al. NATURE CELL BIOLOGY
- Primary Sclerosing Cholangitis
- (2016) Konstantinos N. Lazaridis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling
- (2016) Kenji Kamimoto et al. eLife
- Revisiting Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Clues for a Better Understanding of the “Reactive” Biliary Epithelial Phenotype
- (2016) Luca Fabris et al. Stem Cells International
- Cellular Homeostasis and Repair in the Mammalian Liver
- (2015) Ben Z. Stanger Annual Review of Physiology
- Homeostasis, Inflammation, and Disease Susceptibility
- (2015) Maya E. Kotas et al. CELL
- Orchestrating liver development
- (2015) M. Gordillo et al. DEVELOPMENT
- Liver Stem Cells: Experimental Findings and Implications for Human Liver Disease
- (2015) George K. Michalopoulos et al. GASTROENTEROLOGY
- Determining the fate of hepatic cells by lineage tracing: Facts and pitfalls
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- (2015) Rui Dong et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes
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- (2015) Mina Ogawa et al. NATURE BIOTECHNOLOGY
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- (2015) Wei-Yu Lu et al. NATURE CELL BIOLOGY
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- (2015) Dale I Godfrey et al. NATURE IMMUNOLOGY
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- (2014) Axel R. Concepcion et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2014) Fabian Geisler et al. HEPATOLOGY
- Clonal tracing of Sox9+liver progenitors in mouse oval cell injury
- (2014) Branden D. Tarlow et al. HEPATOLOGY
- The biliary epithelium gives rise to liver progenitor cells
- (2014) Daniel Rodrigo-Torres et al. HEPATOLOGY
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- (2014) James H Tabibian et al. LABORATORY INVESTIGATION
- Stress, Inflammation, and Defense of Homeostasis
- (2014) Raj Chovatiya et al. MOLECULAR CELL
- Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury
- (2014) Johanna R. Schaub et al. Cell Reports
- Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
- (2013) Anatoliy I. Masyuk et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Inhibition of Toll-like receptor 4 suppresses liver injury induced by biliary obstruction and subsequent intraportal lipopolysaccharide injection
- (2013) Shingo Oya et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Recent advances in the morphological and functional heterogeneity of the biliary epithelium
- (2013) Yuyan Han et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Extensive Conversion of Hepatic Biliary Epithelial Cells to Hepatocytes After Near Total Loss of Hepatocytes in Zebrafish
- (2013) Tae–Young Choi et al. GASTROENTEROLOGY
- Regeneration of Liver After Extreme Hepatocyte Loss Occurs Mainly via Biliary Transdifferentiation in Zebrafish
- (2013) Jianbo He et al. GASTROENTEROLOGY
- Vascular cell adhesion molecule 1 expression by biliary epithelium promotes persistence of inflammation by inhibiting effector T-cell apoptosis
- (2013) Simon C. Afford et al. HEPATOLOGY
- Liver regeneration by stem/progenitor cells
- (2013) Tohru Itoh et al. HEPATOLOGY
- Vascular biology of the biliary epithelium
- (2013) Carola M Morell et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
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- (2013) Romina Fiorotto et al. JOURNAL OF HEPATOLOGY
- In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
- (2013) Meritxell Huch et al. NATURE
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- (2013) Ingmar Mederacke et al. Nature Communications
- Liver Progenitor Cells Yield Functional Hepatocytes in Response to Chronic Liver Injury in Mice
- (2012) Regina Español–Suñer et al. GASTROENTEROLOGY
- Up-regulation of microRNA 506 leads to decreased Cl−/HCO3− anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis
- (2012) Jesús M. Banales et al. HEPATOLOGY
- Development of the bile ducts: Essentials for the clinical hepatologist
- (2012) Mario Strazzabosco et al. JOURNAL OF HEPATOLOGY
- CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver
- (2012) Ye Htun Oo et al. JOURNAL OF HEPATOLOGY
- The dynamic biliary epithelia: Molecules, pathways, and disease
- (2012) Steven P. O’Hara et al. JOURNAL OF HEPATOLOGY
- Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
- (2012) Luke Boulter et al. NATURE MEDICINE
- Correction: Expensive Egos: Narcissistic Males Have Higher Cortisol
- (2012) David A. Reinhard et al. PLoS One
- Molecular mechanisms of liver and bile duct development
- (2012) Yiwei Zong et al. Wiley Interdisciplinary Reviews-Developmental Biology
- Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone
- (2011) Fuquan Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Loss of CFTR Affects Biliary Epithelium Innate Immunity and Causes TLR4–NF-κB—Mediated Inflammatory Response in Mice
- (2011) Romina Fiorotto et al. GASTROENTEROLOGY
- A biliary HCO3−umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes
- (2011) Simon Hohenester et al. HEPATOLOGY
- Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
- (2011) Yann Malato et al. JOURNAL OF CLINICAL INVESTIGATION
- A Step Further in the Analysis of Human Bile Proteome
- (2011) Annarita Farina et al. JOURNAL OF PROTEOME RESEARCH
- Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis
- (2011) Tobias Mueller et al. LIVER INTERNATIONAL
- Epithelial-Mesenchymal Interactions in Biliary Diseases
- (2011) Luca Fabris et al. SEMINARS IN LIVER DISEASE
- Bile Ductular Cells Undergoing Cellular Senescence Increase in Chronic Liver Diseases Along With Fibrous Progression
- (2010) Motoko Sasaki et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia
- (2010) Anatoliy I. Masyuk et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Identification and Functional Characterization of TMEM16A, a Ca2+-activated Cl−Channel Activated by Extracellular Nucleotides, in Biliary Epithelium
- (2010) Amal K. Dutta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
- (2010) Kenichiro Furuyama et al. NATURE GENETICS
- Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte
- (2010) Kantima Ninlawan et al. PARASITOLOGY INTERNATIONAL
- OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids
- (2009) Nazzareno Ballatori Frontiers in Bioscience-Landmark
- The enterohepatic circulation of bile acids in mammals: form and functions
- (2009) Alan et al. Frontiers in Bioscience-Landmark
- Mechanisms of Liver Development: Concepts for Understanding Liver Disorders and Design of Novel Therapies
- (2009) Frédéric P. Lemaigre GASTROENTEROLOGY
- Stem Cells and Liver Regeneration
- (2009) Andrew W. Duncan et al. GASTROENTEROLOGY
- Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice
- (2009) Jan S. Tchorz et al. HEPATOLOGY
- Biliary differentiation and bile duct morphogenesis in development and disease
- (2009) Peggy Raynaud et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Lymphocyte recruitment and homing to the liver in primary biliary cirrhosis and primary sclerosing cholangitis
- (2009) Andrea T. Borchers et al. Seminars in Immunopathology
- Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms
- (2008) Shannon Glaser et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors
- (2008) Anatoliy I. Masyuk et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Functional Anatomy of Normal Bile Ducts
- (2008) Mario Strazzabosco et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Cholangiocyte primary cilia in liver health and disease
- (2008) Anatoliy I. Masyuk et al. DEVELOPMENTAL DYNAMICS
- FGF signaling segregates biliary cell-lineage from chick hepatoblasts cooperatively with BMP4 and ECM components in vitro
- (2008) Masaaki Yanai et al. DEVELOPMENTAL DYNAMICS
- Ae2a,b-Deficient Mice Develop Antimitochondrial Antibodies and Other Features Resembling Primary Biliary Cirrhosis
- (2008) January T. Salas et al. GASTROENTEROLOGY
- Bile Salts Control the Antimicrobial Peptide Cathelicidin Through Nuclear Receptors in the Human Biliary Epithelium
- (2008) Emilie D'Aldebert et al. GASTROENTEROLOGY
- Foxl1 is a marker of bipotential hepatic progenitor cells in mice
- (2008) Sara D. Sackett et al. HEPATOLOGY
- Cholangiocarcinoma: Advances in pathogenesis, diagnosis, and treatment
- (2008) Boris Blechacz et al. HEPATOLOGY
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
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