Self-assembled liver organoids recapitulate hepatobiliary organogenesis in vitro

Fluid Flow Regulation of Revascularization and Cellular Organization in a Bioengineered Liver Platform

(2016) Pedro M. Baptista et al.   TISSUE ENGINEERING PART C-METHODS

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

(2015) Meritxell Huch et al.   CELL

Human pluripotent stem cell-derived cholangiocytes

(2015) Akihide Kamiya et al.   CURRENT OPINION IN GASTROENTEROLOGY

Directed differentiation of cholangiocytes from human pluripotent stem cells

(2015) Mina Ogawa et al.   NATURE BIOTECHNOLOGY

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

(2015) Fotios Sampaziotis et al.   NATURE BIOTECHNOLOGY

Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance

(2015) Baltasar Lucendo Villarin et al.   Advanced Healthcare Materials

Modeling human development in 3D culture

(2014) Marius Ader et al.   CURRENT OPINION IN CELL BIOLOGY

On human development: lessons from stem cell systems

(2014) A. Medvinsky et al.   DEVELOPMENT

Therapeutic modulation of Notch signalling — are we there yet?

(2014) Emma R. Andersson et al.   NATURE REVIEWS DRUG DISCOVERY

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biliary Epithelial Cells Play an Essential Role in the Reconstruction of Hepatic Tissue with a Functional Bile Ductular Network

(2013) Takeshi Katsuda et al.   TISSUE ENGINEERING PART A

Developing High-Fidelity Hepatotoxicity Models From Pluripotent Stem Cells

(2013) Claire N. Medine et al.   Stem Cells Translational Medicine

Liver Regenerative Medicine: Advances and Challenges

(2012) Dimitry A. Chistiakov   CELLS TISSUES ORGANS

Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues

(2011) Maren Drewitz et al.   Biotechnology Journal

Humanized mice with ectopic artificial liver tissues

(2011) A. A. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome

(2010) J. J. Hofmann et al.   DEVELOPMENT

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds

(2010) Yunfang Wang et al.   HEPATOLOGY

The use of whole organ decellularization for the generation of a vascularized liver organoid

(2010) Pedro M. Baptista et al.   HEPATOLOGY

Molecular mechanisms of bile duct development

(2010) Yiwei Zong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

(2009) Aline Antoniou et al.   GASTROENTEROLOGY

Biliary differentiation and bile duct morphogenesis in development and disease

(2009) Peggy Raynaud et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Liver-specific inactivation ofNotch2, but notNotch1, compromises intrahepatic bile duct development in mice

(2008) Fabian Geisler et al.   HEPATOLOGY