β-Catenin and interleukin-1β-dependent chemokine (C-X-C motif) ligand 10 production drives progression of disease in a mouse model of congenital hepatic fibrosis

Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease

(2017) Carlo Spirli et al.   JOURNAL OF HEPATOLOGY

Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies

(2016) Cynthia Ju et al.   Cellular & Molecular Immunology

The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity

(2016) Romina Fiorotto et al.   HEPATOLOGY

Macrophage recruitment by fibrocystin-defective biliary epithelial cells promotes portal fibrosis in congenital hepatic fibrosis

(2016) Luigi Locatelli et al.   HEPATOLOGY

A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues

(2016) Yen-Rei A. Yu et al.   PLoS One

CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

(2016) Kyoko Tomita et al.   Scientific Reports

Molecular Mechanisms in Genetically Defined Autoinflammatory Diseases: Disorders of Amplified Danger Signaling

(2015) Adriana Almeida de Jesus et al.   Annual Review of Immunology

Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage

(2015) Carlo Spirli et al.   HEPATOLOGY

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Roles for Chemokines in Liver Disease

(2014) Fabio Marra et al.   GASTROENTEROLOGY

β-catenin regulates NF-κB activity and inflammatory cytokine expression in bronchial epithelial cells treated with lipopolysaccharide

(2014) JAEWOONG JANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis

(2014) Xiang Zhang et al.   JOURNAL OF HEPATOLOGY

Protein kinase a-dependent pSer675 -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis

(2013) Carlo Spirli et al.   HEPATOLOGY

Synergistic Expression of the CXCL10 Gene in Response to IL-1  and IFN-  Involves NF- B, Phosphorylation of STAT1 at Tyr701, and Acetylation of Histones H3 and H4

(2013) S. J. Burke et al.   JOURNAL OF IMMUNOLOGY

Induction of an Inflammatory Loop by Interleukin-1β and Tumor Necrosis Factor-α Involves NF-kB and STAT-1 in Differentiated Human Neuroprogenitor Cells

(2013) Subbiah Pugazhenthi et al.   PLoS One

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice

(2012) Marie Anson et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Development of the bile ducts: Essentials for the clinical hepatologist

(2012) Mario Strazzabosco et al.   JOURNAL OF HEPATOLOGY

Inflammasomes in liver diseases

(2012) Gyongyi Szabo et al.   JOURNAL OF HEPATOLOGY

Polycystic Liver Diseases: Congenital Disorders of Cholangiocyte Signaling

(2011) Mario Strazzabosco et al.   GASTROENTEROLOGY

Epithelial-Mesenchymal Interactions in Biliary Diseases

(2011) Luca Fabris et al.   SEMINARS IN LIVER DISEASE

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation

(2010) Edith Hintermann et al.   JOURNAL OF AUTOIMMUNITY

TNFα and IFNγ Synergistically Enhance Transcriptional Activation ofCXCL10in Human Airway Smooth Muscle Cells via STAT-1, NF-κB, and the Transcriptional Coactivator CREB-binding Protein

(2010) Deborah L. Clarke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shear-induced Interleukin-6 Synthesis in Chondrocytes

(2010) Pu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

ERK1/2-Dependent Vascular Endothelial Growth Factor Signaling Sustains Cyst Growth in Polycystin-2 Defective Mice

(2009) Carlo Spirli et al.   GASTROENTEROLOGY

Lymphoid Enhancer Binding Factor 1 Regulates Transcription through Gene Looping

(2009) K. Yun et al.   JOURNAL OF IMMUNOLOGY

Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1

(2008) Anna-Rachel Gallagher et al.   AMERICAN JOURNAL OF PATHOLOGY

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

E-cadherin controls  -catenin and NF- B transcriptional activity in mesenchymal gene expression

(2008) G. Solanas et al.   JOURNAL OF CELL SCIENCE