Hepatostat: Liver regeneration and normal liver tissue maintenance

Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs

(2016) Kristin A. Sauter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage

(2016) Ahmed Elbediwy et al.   BIOESSAYS

The plastic cellular states of liver cells: Are EpCAM and Lgr5 fit for purpose?

(2016) Meritxell Huch et al.   HEPATOLOGY

Combined systemic elimination of MET and epidermal growth factor receptor signaling completely abolishes liver regeneration and leads to liver decompensation

(2016) Shirish Paranjpe et al.   HEPATOLOGY

The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size

(2016) Lara Planas-Paz et al.   NATURE CELL BIOLOGY

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

(2015) Joan Font-Burgada et al.   CELL

The FXR-FGF19 Gut–Liver Axis as a Novel “Hepatostat”

(2015) Matias A. Avila et al.   GASTROENTEROLOGY

Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers

(2015) Willscott E. Naugler et al.   GASTROENTEROLOGY

Liver Stem Cells: Experimental Findings and Implications for Human Liver Disease

(2015) George K. Michalopoulos et al.   GASTROENTEROLOGY

Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass

(2015) Nicholas M. George et al.   MOLECULAR ENDOCRINOLOGY

Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

(2015) Bruce Wang et al.   NATURE

Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver

(2015) Sofi Eriksson et al.   Nature Communications

Cholic Acid Induces a Cftr Dependent Biliary Secretion and Liver Growth Response in Mice

(2015) Frank A. J. A. Bodewes et al.   PLoS One

Hippo Pathway Activity Influences Liver Cell Fate

(2014) Dean Yimlamai et al.   CELL

Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice

(2014) Junyan Tao et al.   GASTROENTEROLOGY

Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice

(2014) Susagna Padrissa-Altés et al.   GUT

Leukocyte-Specific Protein 1: ANovel Regulator of Hepatocellular Proliferation and Migration Deleted in Human Hepatocellular Carcinoma

(2014) Kelly Koral et al.   HEPATOLOGY

Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regeneration

(2014) Jingling Jin et al.   HEPATOLOGY

Bile Acid Flux Is Necessary for Normal Liver Regeneration

(2014) Willscott E. Naugler   PLoS One

Development of a Chemically Defined Medium and Discovery of New Mitogenic Growth Factors for Mouse Hepatocytes: Mitogenic Effects of FGF1/2 and PDGF

(2014) William C. Bowen et al.   PLoS One

Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli

(2014) Callie A. Norris et al.   PLoS One

Regulation of Liver Growth by Glypican 3, CD81, Hedgehog, and Hhex

(2013) Vishakha S. Bhave et al.   AMERICAN JOURNAL OF PATHOLOGY

TGR5 in cholangiocytes

(2013) Verena Keitel et al.   CURRENT OPINION IN GASTROENTEROLOGY

The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice

(2013) Noémie Péan et al.   HEPATOLOGY

Conditional Genetic Elimination of Hepatocyte Growth Factor in Mice Compromises Liver Regeneration after Partial Hepatectomy

(2013) Kari Nejak-Bowen et al.   PLoS One

To divide or not to divide: revisiting liver regeneration

(2013) Yuichiro Miyaoka et al.   Cell Division

Hypertrophy and Unconventional Cell Division of Hepatocytes Underlie Liver Regeneration

(2012) Yuichiro Miyaoka et al.   CURRENT BIOLOGY

A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration

(2012) Raymond Ng et al.   JOURNAL OF CLINICAL INVESTIGATION

Liver sinusoidal endothelial cell progenitor cells promote liver regeneration in rats

(2012) Lin Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals

(2012) S Moleirinho et al.   ONCOGENE

Hedgehog signaling in cholangiocytes

(2011) Alessia Omenetti et al.   CURRENT OPINION IN GASTROENTEROLOGY

Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells

(2011) Rodolphe Carpentier et al.   GASTROENTEROLOGY

Frequent Aneuploidy Among Normal Human Hepatocytes

(2011) Andrew W. Duncan et al.   GASTROENTEROLOGY

Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo

(2011) Vishakha S. Bhave et al.   HEPATOLOGY

Eight paths of ERK1/2 signalling pathway regulating hepatocyte proliferation in rat liver regeneration

(2011) J. W. LI et al.   JOURNAL OF GENETICS

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

A hepatocyte growth factor receptor (Met)−insulin receptor hybrid governs hepatic glucose metabolism

(2011) Arlee Fafalios et al.   NATURE MEDICINE

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

(2011) B. Mukhopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development

(2010) J Avruch et al.   BRITISH JOURNAL OF CANCER

Distinct proliferative and transcriptional effects of the D-type cyclins in vivo

(2010) Lisa K. Mullany et al.   CELL CYCLE

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

MicroRNAs control hepatocyte proliferation during liver regeneration

(2010) Guisheng Song et al.   HEPATOLOGY

Suppression of liver regeneration and hepatocyte proliferation in hepatocyte-targeted glypican 3 transgenic mice

(2010) Bowen Liu et al.   HEPATOLOGY

Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice

(2010) Begoña Ochoa et al.   HEPATOLOGY

Loss of transforming growth factor β adaptor protein β-2 spectrin leads to delayed liver regeneration in mice

(2010) Arun Thenappan et al.   HEPATOLOGY

The ploidy conveyor of mature hepatocytes as a source of genetic variation

(2010) Andrew W. Duncan et al.   NATURE

Investigation of the Role of Glypican 3 in Liver Regeneration and Hepatocyte Proliferation

(2009) Bowen Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver Regeneration after Partial Hepatectomy

(2009) George K. Michalopoulos   AMERICAN JOURNAL OF PATHOLOGY

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase

(2009) Udayan Apte et al.   HEPATOLOGY

Mechanisms of hepatocyte growth factor-mediated and epidermal growth factor-mediated signaling in transdifferentiation of rat hepatocytes to biliary epithelium

(2008) Pallavi B. Limaye et al.   HEPATOLOGY