Recent advances in the morphological and functional heterogeneity of the biliary epithelium

TGR5 in cholangiocytes

(2013) Verena Keitel et al.   CURRENT OPINION IN GASTROENTEROLOGY

Yes-associated protein regulates the hepatic response after bile duct ligation

(2012) Haibo Bai et al.   HEPATOLOGY

Up-regulation of microRNA 506 leads to decreased Cl−/HCO3− anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis

(2012) Jesús M. Banales et al.   HEPATOLOGY

Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease

(2012) Valerio Nobili et al.   HEPATOLOGY

Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats

(2012) Anastasia Renzi et al.   HEPATOLOGY

Analysis of altered microRNA expression profiles in peripheral blood mononuclear cells from patients with primary biliary cirrhosis

(2012) Baodong Qin et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Multipotent stem/progenitor cells in the human foetal biliary tree

(2012) Rossella Semeraro et al.   JOURNAL OF HEPATOLOGY

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

(2012) Luke Boulter et al.   NATURE MEDICINE

Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors

(2011) Anastasia Renzi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice

(2011) Shannon Glaser et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone

(2011) Fuquan Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma

(2011) Heather Francis et al.   GUT

Role of stem cell factor and granulocyte colony-stimulating factor in remodeling during liver regeneration

(2011) Fanyin Meng et al.   HEPATOLOGY

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

Human hepatic stem cell and maturational liver lineage biology

(2011) Rachael Turner et al.   HEPATOLOGY

Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages

(2011) Guido Carpino et al.   JOURNAL OF ANATOMY

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

(2011) Yann Malato et al.   JOURNAL OF CLINICAL INVESTIGATION

Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms

(2011) Heather L Francis et al.   LABORATORY INVESTIGATION

After Damage of Large Bile Ducts by Gamma-Aminobutyric Acid, Small Ducts Replenish the Biliary Tree by Amplification of Calcium-Dependent Signaling and de Novo Acquisition of Large Cholangiocyte Phenotypes

(2010) Romina Mancinelli et al.   AMERICAN JOURNAL OF PATHOLOGY

Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults

(2010) Alessia Omenetti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes

(2010) Verena Keitel et al.   BIOLOGICAL CHEMISTRY

Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats

(2010) Shannon Glaser et al.   DIGESTIVE AND LIVER DISEASE

Adenosine triphosphate release and purinergic (P2) receptor-mediated secretion in small and large mouse cholangiocytes

(2010) Kangmee Woo et al.   HEPATOLOGY

Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation

(2010) Shannon Glaser et al.   HEPATOLOGY

Activation of alpha1-adrenergic receptors stimulate the growth of small mouse cholangiocytes Via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1

(2010) Gianfranco Alpini et al.   HEPATOLOGY

Molecular mechanisms of bile duct development

(2010) Yiwei Zong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Identification and Functional Characterization of TMEM16A, a Ca2+-activated Cl−Channel Activated by Extracellular Nucleotides, in Biliary Epithelium

(2010) Amal K. Dutta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic Duodenal Homeobox-1 de novo expression drives cholangiocyte neuroendocrine-like transdifferentiation

(2010) Marco Marzioni et al.   JOURNAL OF HEPATOLOGY

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

A novel approach to biliary tract pathology based on similarities to pancreatic counterparts: Is the biliary tract an incomplete pancreas?

(2010) Yasuni Nakanuma   PATHOLOGY INTERNATIONAL

Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1

(2009) Romina Mancinelli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Sox17 Regulates Organ Lineage Segregation of Ventral Foregut Progenitor Cells

(2009) Jason R. Spence et al.   DEVELOPMENTAL CELL

New insights into liver stem cells

(2009) E. Gaudio et al.   DIGESTIVE AND LIVER DISEASE

Taurocholate Feeding to Bile Duct Ligated Rats Prevents Caffeic Acid-Induced Bile Duct Damage by Changes in Cholangiocyte VEGF Expression

(2009) Romina Mancinelli et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cholangiocyte proliferation and liver fibrosis

(2009) Shannon S. Glaser et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Mechanisms of Liver Development: Concepts for Understanding Liver Disorders and Design of Novel Therapies

(2009) Frédéric P. Lemaigre   GASTROENTEROLOGY

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

(2009) B. Spee et al.   GUT

Diferentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation

(2009) Mario Strazzabosco et al.   HEPATOLOGY

Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production

(2009) Alessia Omenetti et al.   HEPATOLOGY

Primary biliary cirrhosis is associated with altered hepatic microRNA expression

(2009) Kerstien A. Padgett et al.   JOURNAL OF AUTOIMMUNITY

EASL Clinical Practice Guidelines: Management of cholestatic liver diseases

(2009)   JOURNAL OF HEPATOLOGY

Morphological and functional heterogeneity of the mouse intrahepatic biliary epithelium

(2009) Shannon S Glaser et al.   LABORATORY INVESTIGATION

Dynamic Signaling Network for the Specification of Embryonic Pancreas and Liver Progenitors

(2009) E. Wandzioch et al.   SCIENCE

Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway

(2008) Heather Francis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms

(2008) Shannon Glaser et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Embryology of Extra- and Intrahepatic Bile Ducts, the Ductal plate

(2008) T. Roskams et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

The stem cell niche of human livers: Symmetry between development and regeneration

(2008) Lili Zhang et al.   HEPATOLOGY

Insulin-like growth factor-1 isoforms in rat hepatocytes and cholangiocytes and their involvement in protection against cholestatic injury

(2008) Manuela Gatto et al.   LABORATORY INVESTIGATION

Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation

(2007) Sharon DeMorrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY