The many faces of tumor necrosis factor signaling in the intestinal epithelium
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Title
The many faces of tumor necrosis factor signaling in the intestinal epithelium
Authors
Keywords
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Journal
GENES AND IMMUNITY
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-03-08
DOI
10.1038/s41435-019-0057-0
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Note: Only part of the references are listed.- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort
- (2018) Kelly A. Shaw et al. GENES AND IMMUNITY
- The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis
- (2018) Laura Watts et al. GENES AND IMMUNITY
- RIP kinase 1–dependent endothelial necroptosis underlies systemic inflammatory response syndrome
- (2018) Matija Zelic et al. JOURNAL OF CLINICAL INVESTIGATION
- Local synthesis of immunosuppressive glucocorticoids in the intestinal epithelium regulates anti-viral immune responses
- (2018) Juan Huang et al. CELLULAR IMMUNOLOGY
- TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling
- (2018) Daniela Siegmund et al. Cell Death & Disease
- Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor–Mediated Destruction of Intestinal Epithelial Cells
- (2017) Thomas Grabinger et al. GASTROENTEROLOGY
- Transcriptome analysis of ankylosing spondylitis patients before and after TNF-α inhibitor therapy reveals the pathways affected
- (2017) X B Wang et al. GENES AND IMMUNITY
- Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation
- (2017) Conor M. Henry et al. MOLECULAR CELL
- Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency
- (2017) Evangelos Giampazolias et al. NATURE CELL BIOLOGY
- Glucocorticosteroid therapy in inflammatory bowel diseases: From clinical practice to molecular biology
- (2017) Karen Dubois-Camacho et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis
- (2017) Derrick D Eichele et al. WORLD JOURNAL OF GASTROENTEROLOGY
- RIPK3 Mediates Necroptosis during Embryonic Development and Postnatal Inflammation in Fadd -Deficient Mice
- (2017) Qun Zhao et al. Cell Reports
- TRAF2 multitasking in TNF receptor-induced signaling to NF-κB, MAP kinases and cell death
- (2016) Alice Borghi et al. BIOCHEMICAL PHARMACOLOGY
- RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
- (2016) K Newton et al. CELL DEATH AND DIFFERENTIATION
- The MUC1 mucin specifically inhibits activation of the NLRP3 inflammasome
- (2016) G Z Ng et al. GENES AND IMMUNITY
- GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis
- (2016) J P Hussman et al. GENES AND IMMUNITY
- NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
- (2016) Katerina Vlantis et al. IMMUNITY
- More to Life than NF-κB in TNFR1 Signaling
- (2016) Adrian T. Ting et al. TRENDS IN IMMUNOLOGY
- Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases
- (2016) Ulrike Billmeier et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis
- (2016) Daniela Siegmund et al. Cell Death & Disease
- Inactivation of CYLD in intestinal epithelial cells exacerbates colitis-associated colorectal carcinogenesis - a short report
- (2016) Demetrios N. Karatzas et al. CELLULAR ONCOLOGY
- Cell death at the intestinal epithelial front line
- (2015) Maria Eugenia Delgado et al. FEBS Journal
- Association of inflammatory cytokine gene polymorphisms with inflammatory bowel disease in a Moroccan cohort
- (2015) N Senhaji et al. GENES AND IMMUNITY
- NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
- (2015) Yves Dondelinger et al. MOLECULAR CELL
- Necroptosis and its role in inflammation
- (2015) Manolis Pasparakis et al. NATURE
- Anti-TNF levels and anti-drug antibodies, immunosuppressants and clinical outcomes in inflammatory bowel disease
- (2015) Christina Ha et al. Expert Review of Gastroenterology & Hepatology
- Paneth cells
- (2014) Johan H. van Es et al. CURRENT BIOLOGY
- TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants – past, present and future
- (2014) Lisa M. Sedger et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Targeting the Fc receptor in autoimmune disease
- (2014) Xinrui Li et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Pleiotropic functions of TNF- in the regulation of the intestinal epithelial response to inflammation
- (2014) M. Leppkes et al. INTERNATIONAL IMMUNOLOGY
- Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis
- (2014) R. Kajino-Sakamoto et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
- (2014) S. B. Berger et al. JOURNAL OF IMMUNOLOGY
- RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
- (2014) Nozomi Takahashi et al. NATURE
- RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
- (2014) Marius Dannappel et al. NATURE
- Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis
- (2014) K. Newton et al. SCIENCE
- TNF and MAP kinase signalling pathways
- (2014) Guadalupe Sabio et al. SEMINARS IN IMMUNOLOGY
- Epithelial Cell Shedding and Barrier Function
- (2014) J. M. Williams et al. VETERINARY PATHOLOGY
- Immunopathology of inflammatory bowel disease
- (2014) Kori L Wallace WORLD JOURNAL OF GASTROENTEROLOGY
- Necroptosis Is Active in Children With Inflammatory Bowel Disease and Contributes to Heighten Intestinal Inflammation
- (2013) Maria Pierdomenico et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- The TWEAK-Fn14 system as a potential drug target
- (2013) Harald Wajant BRITISH JOURNAL OF PHARMACOLOGY
- RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
- (2013) Y Dondelinger et al. CELL DEATH AND DIFFERENTIATION
- TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis
- (2013) Liping Su et al. GASTROENTEROLOGY
- Circulating CD4+and CD8+T cells are activated in inflammatory bowel disease and are associated with plasma markers of inflammation
- (2013) Nicholas T. Funderburg et al. IMMUNOLOGY
- ERK controls epithelial cell death receptor signalling and cellular FLICE-like inhibitory protein (c-FLIP) in ulcerative colitis
- (2013) Jakob Benedict Seidelin et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine
- (2013) Denise L. Faustman et al. Frontiers in Immunology
- Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
- (2012) Claudia Günther et al. GUT
- Role of NF-κB in epithelial biology
- (2012) Manolis Pasparakis IMMUNOLOGICAL REVIEWS
- Regulation of NF-κB by deubiquitinases
- (2012) Edward W. Harhaj et al. IMMUNOLOGICAL REVIEWS
- Neutralization of Membrane TNF, but Not Soluble TNF, Is Crucial for the Treatment of Experimental Colitis
- (2012) Clémentine Perrier et al. INFLAMMATORY BOWEL DISEASES
- Opposite Role of Tumor Necrosis Factor Receptors in Dextran Sulfate Sodium-Induced Colitis in Mice
- (2012) Ke Wang et al. PLoS One
- c-FLIP Maintains Tissue Homeostasis by Preventing Apoptosis and Programmed Necrosis
- (2012) X. Piao et al. Science Signaling
- Extra-adrenal glucocorticoids and mineralocorticoids: evidence for local synthesis, regulation, and function
- (2011) Matthew D. Taves et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis
- (2011) Steven J. McElroy et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Regulation of CD95/Fas signaling at the DISC
- (2011) I N Lavrik et al. CELL DEATH AND DIFFERENTIATION
- Tumor necrosis factor receptor cross-talk
- (2011) Petrus J. W. Naudé et al. FEBS Journal
- TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8
- (2011) Aminah Ikner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cellular FLICE-inhibitory Protein (cFLIP) Isoforms Block CD95- and TRAIL Death Receptor-induced Gene Induction Irrespective of Processing of Caspase-8 or cFLIP in the Death-inducing Signaling Complex
- (2011) Shyam M. Kavuri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TNF -induced noncanonical NF- B activation is attenuated by RIP1 through stabilization of TRAF2
- (2011) J.-Y. Kim et al. JOURNAL OF CELL SCIENCE
- FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
- (2011) Patrick-Simon Welz et al. NATURE
- Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
- (2011) Claudia Günther et al. NATURE
- A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
- (2011) Jae Man Lee et al. NATURE
- Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
- (2011) Andrew Oberst et al. NATURE
- Caspase 8 inhibits programmed necrosis by processing CYLD
- (2011) Marie Anne O’Donnell et al. NATURE CELL BIOLOGY
- Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
- (2011) M. Roulis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
- (2010) N Vanlangenakker et al. CELL DEATH AND DIFFERENTIATION
- Lipopolysaccharide induces intestinal glucocorticoid synthesis in a TNFα-dependent manner
- (2010) Mario Noti et al. FASEB JOURNAL
- Golimumab as the first monthly subcutaneous fully human anti-TNF-α antibody in the treatment of inflammatory arthropathies
- (2010) Gabor Hutas Immunotherapy
- Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL
- (2010) Nicolai Fricker et al. JOURNAL OF CELL BIOLOGY
- TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis
- (2010) Mario Noti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis
- (2010) Lars Vereecke et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dynamics within the CD95 death-inducing signaling complex decide life and death of cells
- (2010) Leo Neumann et al. Molecular Systems Biology
- New insights into apoptosis signaling by Apo2L/TRAIL
- (2010) F Gonzalvez et al. ONCOGENE
- The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis
- (2010) P. Vandenabeele et al. Science Signaling
- Intestinal epithelial cells in inflammatory bowel diseases
- (2010) Giulia Roda WORLD JOURNAL OF GASTROENTEROLOGY
- Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
- (2009) Andrea Haegebarth et al. AMERICAN JOURNAL OF PATHOLOGY
- NEMO/IKKγ regulates an early NF-κB-independent cell-death checkpoint during TNF signaling
- (2009) D Legarda-Addison et al. CELL DEATH AND DIFFERENTIATION
- The epidemiology of glucocorticoid-associated adverse events
- (2009) Allyson K McDonough et al. CURRENT OPINION IN RHEUMATOLOGY
- Lack of TNFR2 expression by CD4+T cells exacerbates experimental colitis
- (2009) Johanna Dayer Schneider et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Soluble TNF-α but not transmembrane TNF-α sensitizes T cells for enhanced activation-induced cell death
- (2009) Stefan Müller et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Membrane Tumor Necrosis Factor (TNF) Induces p100 Processing via TNF Receptor-2 (TNFR2)
- (2009) Hilka Rauert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation
- (2009) J. C. Hoffmann et al. MOLECULAR AND CELLULAR BIOLOGY
- Anti-TNF therapies: a comprehensive analysis of adverse effects associated with immunosuppression
- (2009) Victoria Connor RHEUMATOLOGY INTERNATIONAL
- Extra-adrenal glucocorticoid synthesis in the intestinal epithelium: more than a drop in the ocean?
- (2009) Mario Noti et al. Seminars in Immunopathology
- RIP Kinases Initiate Programmed Necrosis
- (2009) L. Galluzzi et al. Journal of Molecular Cell Biology
- Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium
- (2008) Laurens G. van der Flier et al. Annual Review of Physiology
- The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation
- (2008) Lianyun Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- TNF-α Induces Two Distinct Caspase-8 Activation Pathways
- (2008) Lai Wang et al. CELL
- Cell cycle-dependent regulation of extra-adrenal glucocorticoid synthesis in murine intestinal epithelial cells
- (2008) Atanas G. Atanasov et al. FASEB JOURNAL
- Transcriptional and post-translational regulation of Flip, an inhibitor of Fas-mediated apoptosis, in human gut inflammation
- (2008) F Caprioli et al. GUT
- CD95 Stimulation Results in the Formation of a Novel Death Effector Domain Protein-containing Complex
- (2008) Inna N. Lavrik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα
- (2008) James E. Vince et al. JOURNAL OF CELL BIOLOGY
- Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
- (2008) Brian J Zarnegar et al. NATURE IMMUNOLOGY
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