Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation

Title
Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation
Authors
Keywords
apoptosis, Caspase-8, cell death, cytokines, death receptors, FADDosome, NF-κB, Inflammation, RIPK1, TRAIL
Journal
MOLECULAR CELL
Volume 65, Issue 4, Pages 715-729.e5
Publisher
Elsevier BV
Online
2017-02-17
DOI
10.1016/j.molcel.2017.01.022

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