Food-Derived Bioactive Peptides in Human Health: Challenges and Opportunities

Nutraceuticals: opening the debate for a regulatory framework

(2018) Antonello Santini et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Exploration of collagen recovered from animal by-products as a precursor of bioactive peptides: Successes and challenges

(2018) Yu Fu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Structural characteristics of low bitter and high umami protein hydrolysates prepared from bovine muscle and porcine plasma

(2018) Yu Fu et al.   FOOD CHEMISTRY

Bioactive properties of fermented donkey milk, before and after in vitro simulated gastrointestinal digestion

(2018) Maria Aspri et al.   FOOD CHEMISTRY

Hydrolyzed Formula Compared With Standard Formula for Preterm Infants

(2018) Derek H. C. Ng et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Beef Protein-Derived Peptides as Bitter Taste Receptor T2R4 Blockers

(2018) Chunlei Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Egg proteins: fractionation, bioactive peptides and allergenicity

(2018) Chang Chang et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Dietary Supplements: Regulatory Challenges and Research Resources

(2018) Johanna Dwyer et al.   Nutrients

Health Claims on Foods in Canada

(2018) Mary R. L'Abbé et al.   JOURNAL OF NUTRITION

Evidence for Health Claims: A Perspective from the Australia–New Zealand Region

(2018) Linda C. Tapsell   JOURNAL OF NUTRITION

GRAS from the ground up: Review of the Interim Pilot Program for GRAS notification

(2017) Paul R. Hanlon et al.   FOOD AND CHEMICAL TOXICOLOGY

Improving the antioxidant properties of quinoa flour through fermentation with selected autochthonous lactic acid bacteria

(2017) Carlo Giuseppe Rizzello et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Assessment of multifunctional activity of bioactive peptides derived from fermented milk by specific Lactobacillus plantarum strains

(2017) J.E. Aguilar-Toalá et al.   JOURNAL OF DAIRY SCIENCE

Reactivity of peptides within the food matrix

(2017) Jean Paul Kamdem et al.   JOURNAL OF FOOD BIOCHEMISTRY

Effect of deamidation-induced modification on umami and bitter taste of wheat gluten hydrolysates

(2017) Bo-Ye Liu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Functional foods and dietary supplements for the management of dyslipidaemia

(2017) Paola M. Hunter et al.   Nature Reviews Endocrinology

Potential Use of Food Protein-Derived Peptides in the Treatment of Inflammatory Diseases

(2017) Lourdes Santiago-Lopez et al.   PROTEIN AND PEPTIDE LETTERS

Regulation profile of the intestinal peptide transporter 1 (PepT1)

(2017) Chun-Yang Wang et al.   Drug Design Development and Therapy

Effect of cooking and simulated gastrointestinal digestion on the activity of generated bioactive peptides in aged beef meat

(2017) Leticia Mora et al.   Food & Function

Microalgae as healthy ingredients for functional food: a review

(2017) J. Matos et al.   Food & Function

Prevention and Management of Cow’s Milk Allergy in Non-Exclusively Breastfed Infants

(2017) Yvan Vandenplas   Nutrients

Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management

(2017) Arun Chaudhury et al.   Frontiers in Endocrinology

Peptide Fractions Obtained from Rice By-Products by Means of an Environment-Friendly Process Show In Vitro Health-Related Bioactivities

(2017) Maura Ferri et al.   PLoS One

Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

(2016) P. Lundquist et al.   ADVANCED DRUG DELIVERY REVIEWS

Myosin light chain kinase mediates intestinal barrier dysfunction via occludin endocytosis during anoxia/reoxygenation injury

(2016) Younggeon Jin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Defining ‘nutraceuticals’: neither nutritious nor pharmaceutical

(2016) Jeffrey K. Aronson   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pathways of protein and lipid receptor-mediated transcytosis in drug delivery

(2016) Roland Thuenauer et al.   Expert Opinion on Drug Delivery

Production of an antimicrobial peptide derived from slaughterhouse by-product and its potential application on meat as preservative

(2016) Rémi Przybylski et al.   FOOD CHEMISTRY

Bioactive peptides with ACE-I and antioxidant activity produced from milk proteolysis

(2016) Alaa Mohamed Abd El-Fattah et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

Impact of in Vitro Gastrointestinal Digestion and Transepithelial Transport on Antioxidant and ACE-Inhibitory Activities of Brewer’s Spent Yeast Autolysate

(2016) Elsa F. Vieira et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives

(2016) Abdul Muheem et al.   SAUDI PHARMACEUTICAL JOURNAL

Functional Food and Nutraceutical Registration Processes in Japan and China: A Diffusion of Innovation Perspective

(2016) Darshika Patel et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

The Structure and Enzyme Characteristics of a Recombinant Leucine Aminopeptidase rLap1 from Aspergillus sojae and Its Application in Debittering

(2015) Wei-Qian Huang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Antioxidant and ACE Inhibitory Bioactive Peptides Purified from Egg Yolk Proteins

(2015) Marwa Yousr et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Enhanced stability of oral insulin in targeted peptide ligand trimethyl chitosan nanoparticles against trypsin

(2015) Jiexiu Chen et al.   JOURNAL OF MICROENCAPSULATION

Role of intestinal brush border peptidases in the simulated digestion of milk proteins

(2015) Gianluca Picariello et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Twenty years of theMEROPSdatabase of proteolytic enzymes, their substrates and inhibitors

(2015) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Bioactive peptides released by in vitro digestion of standard and hydrolyzed infant formulas

(2015) Yasuaki Wada et al.   PEPTIDES

Breaking the intestinal barrier to deliver drugs

(2015) P. Artursson et al.   SCIENCE

Enhancement of antioxidant properties of two soybean varieties of Sikkim Himalayan region by proteolytic Bacillus subtilis fermentation

(2015) Samurailatpam Sanjukta et al.   Journal of Functional Foods

Bioactive peptides and protein hydrolysates: research trends and challenges for application as nutraceuticals and functional food ingredients

(2015) Eunice CY Li-Chan   Current Opinion in Food Science

Are intact peptides absorbed from the healthy gut in the adult human?

(2015) Warren M. Miner-Williams et al.   NUTRITION RESEARCH REVIEWS

Bioactive dietary peptides and amino acids in inflammatory bowel disease

(2014) Hua Zhang et al.   AMINO ACIDS

Regulatory Frameworks for Functional Food and Supplements

(2014) Jill E. Hobbs et al.   CANADIAN JOURNAL OF AGRICULTURAL ECONOMICS-REVUE CANADIENNE D AGROECONOMIE

Fermented food in the context of a healthy diet

(2014) Frédéric Leroy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Hydrolysate from Eggshell Membrane Ameliorates Intestinal Inflammation in Mice

(2014) Yaning Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Beneficial Effects of Simulated Gastro-Intestinal Digests of Fried Egg and Its Fractions on Blood Pressure, Plasma Lipids and Oxidative Stress in Spontaneously Hypertensive Rats

(2014) Forough Jahandideh et al.   PLoS One

Purifying biopharmaceuticals: knowledge-based chromatographic process development

(2014) Alexander T. Hanke et al.   TRENDS IN BIOTECHNOLOGY

Angiotensin I Converting Enzyme Inhibitory Peptides Obtained afterIn VitroHydrolysis of Pea (Pisum sativumvar. Bajka) Globulins

(2014) Anna Jakubczyk et al.   Biomed Research International

Food-Derived Bioactive Peptides on Inflammation and Oxidative Stress

(2014) Subhadeep Chakrabarti et al.   Biomed Research International

Impact of milk processing on the generation of peptides during digestion

(2013) Katrin A. Kopf-Bolanz et al.   INTERNATIONAL DAIRY JOURNAL

Transport of IRW, an Ovotransferrin-Derived Antihypertensive Peptide, in Human Intestinal Epithelial Caco-2 Cells

(2013) Satyanarayana Bejjani et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oral Delivery of Bioencapsulated Proteins Across Blood–Brain and Blood–Retinal Barriers

(2013) Neha Kohli et al.   MOLECULAR THERAPY

Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery

(2013) E. M. Pridgen et al.   Science Translational Medicine

Bioinformatics: Current perspectives and future directions for food and nutritional research facilitated by a Food-Wiki database

(2013) Thérèse A. Holton et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Food proteins as a source of bioactive peptides with diverse functions

(2012) Kay J. Rutherfurd-Markwick   BRITISH JOURNAL OF NUTRITION

Bioactive Peptides: Synthesis, Properties, and Applications in the Packaging and Preservation of Food

(2012) Paula Judith Perez Espitia et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Bitter Taste Inhibiting Agents for Whey Protein Hydrolysate and Whey Protein Hydrolysate Beverages

(2012) Pattarin Leksrisompong et al.   JOURNAL OF FOOD SCIENCE

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

Specificity of Carboxypeptidases from Actinomucor elegans and Their Debittering Effect on Soybean Protein Hydrolysates

(2011) Jing Fu et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides

(2011) Dominic Agyei et al.   BIOTECHNOLOGY ADVANCES

QSAR-aided in silico approach in evaluation of food proteins as precursors of ACE inhibitory peptides

(2011) Yuchen Gu et al.   FOOD RESEARCH INTERNATIONAL

The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters

(2010) Stefanie Geissler et al.   FEBS Journal

Angiotensin-I-converting enzyme inhibitory activity and bitterness of enzymatically-produced hydrolysates of shrimp (Pandalopsis dispar) processing byproducts investigated by Taguchi design

(2010) Imelda W.Y. Cheung et al.   FOOD CHEMISTRY

Purification and characterisation of angiotensin I converting enzyme (ACE) inhibitory peptides derived from enzymatic hydrolysate of ovotransferrin

(2010) Kaustav Majumder et al.   FOOD CHEMISTRY

How the US Food and Drug Administration evaluates the scientific evidence for health claims

(2010) Kathleen C Ellwood et al.   NUTRITION REVIEWS

New insights into the immunological effects of food bioactive peptides in animal models of intestinal inflammation

(2010) Fermín Sánchez de Medina et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Role of regulatory agencies

(2009) Jay Epstein et al.   BIOLOGICALS

Bitter peptides and bitter taste receptors

(2009) K. Maehashi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae

(2009) Sam Maher et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Biofunctional Properties of Bioactive Peptides of Milk Origin

(2009) E. Haque et al.   FOOD REVIEWS INTERNATIONAL

ANGIOTENSIN I-CONVERTING ENZYME (ACE) INHIBITORY PEPTIDES FROM WHEY FERMENTED BY LACTOBACILLUS SPECIES

(2009) J.E. AHN et al.   JOURNAL OF FOOD BIOCHEMISTRY

Bioactive peptides: signaling the future

(2009) K Fields et al.   Journal of Cosmetic Dermatology

Bioactive peptides and proteins from foods: indication for health effects

(2008) Niels Peter Möller et al.   EUROPEAN JOURNAL OF NUTRITION

The possible roles of food-derived bioactive peptides in reducing the risk of cardiovascular disease

(2008) Kati Erdmann et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY