Breaking the intestinal barrier to deliver drugs

Model for the Architecture of Claudin-Based Paracellular Ion Channels through Tight Junctions

(2015) Hiroshi Suzuki et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin

(2015) Y. Saitoh et al.   SCIENCE

A claudin 3 and claudin 4-targeted Clostridium perfringens protoxin is selectively cytotoxic to PSA-producing prostate cancer cells

(2014) Victor Romanov et al.   CANCER LETTERS

A Synthetic Peptide Corresponding to the Extracellular Loop 2 Region of Claudin-4 Protects against Clostridium perfringens EnterotoxinIn VitroandIn Vivo

(2014) Archana Shrestha et al.   INFECTION AND IMMUNITY

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

The role of molecular remodeling in differential regulation of tight junction permeability

(2014) Jerrold R. Turner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Paracellular barrier and channel functions of TJ claudins in organizing biological systems: Advances in the field of barriology revealed in knockout mice

(2014) Atsushi Tamura et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tissue distribution and safety evaluation of a claudin-targeting molecule, the C-terminal fragment of Clostridium perfringens enterotoxin

(2013) Xiangru Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition

(2012) Masami Wada et al.   GASTROENTEROLOGY

Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury

(2012) Matthew Campbell et al.   Nature Communications