Molecular and physiological basis of Saccharomyces cerevisiae tolerance to adverse lignocellulose-based process conditions

HAA1 and PRS3 overexpression boosts yeast tolerance towards acetic acid improving xylose or glucose consumption: unravelling the underlying mechanisms

(2018) Joana T. Cunha et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Expression of Gre2p improves tolerance of engineered xylose-fermenting Saccharomyces cerevisiae to glycolaldehyde under xylose metabolism

(2018) Lahiru N. Jayakody et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A novel hybrid first and second generation hemicellulosic bioethanol production process through steam treatment of dried sorghum biomass

(2018) Jérémie Damay et al.   BIORESOURCE TECHNOLOGY

Disruption of the transcription factors Thi2p and Nrm1p alleviates the post-glucose effect on xylose utilization in Saccharomyces cerevisiae

(2018) Shan Wei et al.   Biotechnology for Biofuels

Tolerant industrial yeast Saccharomyces cerevisiae posses a more robust cell wall integrity signaling pathway against 2-furaldehyde and 5-(hydroxymethyl)-2-furaldehyde

(2018) Z. Lewis Liu et al.   JOURNAL OF BIOTECHNOLOGY

A semi-synthetic regulon enables rapid growth of yeast on xylose

(2018) Venkatesh Endalur Gopinarayanan et al.   Nature Communications

Glucose repression can be alleviated by reducing glucose phosphorylation rate in Saccharomyces cerevisiae

(2018) Stephan Lane et al.   Scientific Reports

Pdr18 is involved in yeast response to acetic acid stress counteracting the decrease of plasma membrane ergosterol content and order

(2018) Cláudia P. Godinho et al.   Scientific Reports

Adaptive Response and Tolerance to Acetic Acid in Saccharomyces cerevisiae and Zygosaccharomyces bailii: A Physiological Genomics Perspective

(2018) Margarida Palma et al.   Frontiers in Microbiology

Integral valorization of vine pruning residue by sequential autohydrolysis stages

(2017) Meirielly S. Jesus et al.   JOURNAL OF CLEANER PRODUCTION

Metabolic engineering of a haploid strain derived from a triploid industrial yeast for producing cellulosic ethanol

(2017) Soo Rin Kim et al.   METABOLIC ENGINEERING

Profiling of Saccharomyces cerevisiae transcription factors for engineering the resistance of yeast to lignocellulose-derived inhibitors in biomass conversion

(2017) Guochao Wu et al.   Microbial Cell Factories

Msn2/4 regulate expression of glycolytic enzymes and control transition from quiescence to growth

(2017) Zheng Kuang et al.   eLife

ALD5, PAD1, ATF1 and ATF2 facilitate the catabolism of coniferyl aldehyde, ferulic acid and p-coumaric acid in Saccharomyces cerevisiae

(2017) Peter Temitope Adeboye et al.   Scientific Reports

RNA-Seq-based transcriptomic and metabolomic analysis reveal stress responses and programmed cell death induced by acetic acid in Saccharomyces cerevisiae

(2017) Yachen Dong et al.   Scientific Reports

Sphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress

(2016) J. F. Guerreiro et al.   BIOCHEMICAL JOURNAL

Simultaneous Saccharification and Fermentation of Hydrothermal Pretreated Lignocellulosic Biomass: Evaluation of Process Performance Under Multiple Stress Conditions

(2016) Maikon Kelbert et al.   BioEnergy Research

Optimization of an acetate reduction pathway for producing cellulosic ethanol by engineered yeast

(2016) Guo-Chang Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Identification and functional evaluation of the reductases and dehydrogenases from Saccharomyces cerevisiae involved in vanillin resistance

(2016) Xinning Wang et al.   BMC BIOTECHNOLOGY

Advances in mechanisms and modifications for rendering yeast thermotolerance

(2016) Liman Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Control ofSaccharomyces cerevisiaepre-tRNA processing by environmental conditions

(2016) Dominika Foretek et al.   RNA

Compounds inhibiting the bioconversion of hydrothermally pretreated lignocellulose

(2015) Ja Kyong Ko et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Contribution of PRS3, RPB4 and ZWF1 to the resistance of industrial Saccharomyces cerevisiae CCUG53310 and PE-2 strains to lignocellulosic hydrolysate-derived inhibitors

(2015) Joana T. Cunha et al.   BIORESOURCE TECHNOLOGY

Metabolic engineering of Saccharomyces cerevisiae ethanol strains PE-2 and CAT-1 for efficient lignocellulosic fermentation

(2015) Aloia Romaní et al.   BIORESOURCE TECHNOLOGY

Lignocellulosic bioethanol production with revalorization of low-cost agroindustrial by-products as nutritional supplements

(2015) Maikon Kelbert et al.   INDUSTRIAL CROPS AND PRODUCTS

Yeast Tolerance to Various Stresses Relies on the Trehalose-6P Synthase (Tps1) Protein, Not on Trehalose

(2015) Marjorie Petitjean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YNL134CfromSaccharomyces cerevisiaeencodes a novel protein with aldehyde reductase activity for detoxification of furfural derived from lignocellulosic biomass

(2015) Xianxian Zhao et al.   YEAST

Deletion ofPHO13, Encoding Haloacid Dehalogenase Type IIA Phosphatase, Results in Upregulation of the Pentose Phosphate Pathway in Saccharomyces cerevisiae

(2014) Soo Rin Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Flocculation Causes Inhibitor Tolerance in Saccharomyces cerevisiae for Second-Generation Bioethanol Production

(2014) Johan O. Westman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

High temperature stimulates acetic acid accumulation and enhances the growth inhibition and ethanol production by Saccharomyces cerevisiae under fermenting conditions

(2014) Ji-Min Woo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Industrial robust yeast isolates with great potential for fermentation of lignocellulosic biomass

(2014) Francisco B. Pereira et al.   BIORESOURCE TECHNOLOGY

Physiological response ofSaccharomyces cerevisiaeto weak acids present in lignocellulosic hydrolysate

(2014) Zhongpeng Guo et al.   FEMS YEAST RESEARCH

Integrated approach for effective bioethanol production using whole slurry from autohydrolyzed Eucalyptus globulus wood at high-solid loadings

(2014) Aloia Romaní et al.   FUEL

Importance of glucose-6-phosphate dehydrogenase (G6PDH) for vanillin tolerance in Saccharomyces cerevisiae

(2014) Trinh Thi My Nguyen et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Genome-wide screening of Saccharomyces cerevisiae genes required to foster tolerance towards industrial wheat straw hydrolysates

(2014) Francisco B. Pereira et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Phenotypic characterisation of Saccharomyces spp. yeast for tolerance to stresses encountered during fermentation of lignocellulosic residues to produce bioethanol

(2014) Tithira T Wimalasena et al.   Microbial Cell Factories

Development of a GIN11/FRT-based multiple-gene integration technique affording inhibitor-tolerant, hemicellulolytic, xylose-utilizing abilities to industrial Saccharomyces cerevisiaestrains for ethanol production from undetoxified lignocellulosic hemicelluloses

(2014) Tomohisa Hasunuma et al.   Microbial Cell Factories

The diverse role of Pdr12 in resistance to weak organic acids

(2014) Yvonne Nygård et al.   YEAST

Genomic and transcriptome analyses reveal that MAPK- and phosphatidylinositol-signaling pathways mediate tolerance to 5-hydroxymethyl-2-furaldehyde for industrial yeast Saccharomyces cerevisiae

(2014) Qian Zhou et al.   Scientific Reports

Re-assessment of YAP1 and MCR1 contributions to inhibitor tolerance in robust engineered Saccharomyces cerevisiae fermenting undetoxified lignocellulosic hydrolysate

(2014) Valeria Wallace-Salinas et al.   AMB Express

The chemical nature of phenolic compounds determines their toxicity and induces distinct physiological responses in Saccharomyces cerevisiae in lignocellulose hydrolysates

(2014) Peter Temitope Adeboye et al.   AMB Express

Stress tolerance and growth physiology of yeast strains from the Brazilian fuel ethanol industry

(2013) B. E. Della-Bianca et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Roles of the Yap1 Transcription Factor and Antioxidants in Saccharomyces cerevisiae's Tolerance to Furfural and 5-Hydroxymethylfurfural, Which Function as Thiol-Reactive Electrophiles Generating Oxidative Stress

(2013) D. Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Phenotypic selection of a wild Saccharomyces cerevisiae strain for simultaneous saccharification and co-fermentation of AFEX™ pretreated corn stover

(2013) Mingjie Jin et al.   Biotechnology for Biofuels

The influence of HMF and furfural on redox-balance and energy-state of xylose-utilizing Saccharomyces cerevisiae

(2013) Magnus Ask et al.   Biotechnology for Biofuels

Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering

(2013) Mekonnen M Demeke et al.   Biotechnology for Biofuels

Combining inhibitor tolerance and D-xylose fermentation in industrial Saccharomyces cerevisiae for efficient lignocellulose-based bioethanol production

(2013) Mekonnen M Demeke et al.   Biotechnology for Biofuels

Activation of signaling pathways related to cell wall integrity and multidrug resistance by organic solvent in Saccharomyces cerevisiae

(2013) Nao Nishida et al.   CURRENT GENETICS

A kinetic model of catabolic adaptation and protein reprofiling inSaccharomyces cerevisiaeduring temperature shifts

(2013) Femke I. C. Mensonides et al.   FEBS Journal

Bioconversion of Beetle-Killed Lodgepole Pine Using SPORL: Process Scale-up Design, Lignin Coproduct, and High Solids Fermentation without Detoxification

(2013) Haifeng Zhou et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Vanillin causes the activation of Yap1 and mitochondrial fragmentation in Saccharomyces cerevisiae

(2013) Trinh Thi My Nguyen et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Vanillin Inhibits Translation and Induces Messenger Ribonucleoprotein (mRNP) Granule Formation in Saccharomyces cerevisiae: Application and Validation of High-Content, Image-Based Profiling

(2013) Aya Iwaki et al.   PLoS One

Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid Stress

(2013) Lina Lindberg et al.   PLoS One

Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid

(2013) Sergio Giannattasio et al.   Frontiers in Microbiology

Biomass Conversion Inhibitors Furfural and 5-Hydroxymethylfurfural Induce Formation of Messenger RNP Granules and Attenuate Translation Activity in Saccharomyces cerevisiae

(2012) Aya Iwaki et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Quantitative Analysis of the Modes of Growth Inhibition by Weak Organic Acids in Saccharomyces cerevisiae

(2012) Azmat Ullah et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The use of high-solids loadings in biomass pretreatment-a review

(2012) Alicia A. Modenbach et al.   BIOTECHNOLOGY AND BIOENGINEERING

A strain of Saccharomyces cerevisiae evolved for fermentation of lignocellulosic biomass displays improved growth and fermentative ability in high solids concentrations and in the presence of inhibitory compounds

(2012) Gary M Hawkins et al.   Biotechnology for Biofuels

Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae

(2012) Thorsten Subtil et al.   Biotechnology for Biofuels

Inhibitor tolerance and flocculation of a yeast strain suitable for second generation bioethanol production

(2012) Johan O. Westman et al.   ELECTRONIC JOURNAL OF BIOTECHNOLOGY

A constraint-based model analysis of the metabolic consequences of increased NADPH oxidation in Saccharomyces cerevisiae

(2012) Magalie Celton et al.   METABOLIC ENGINEERING

Biology of the Heat Shock Response and Protein Chaperones: Budding Yeast (Saccharomyces cerevisiae) as a Model System

(2012) J. Verghese et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways

(2012) Yidi Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Decreased Xylitol Formation during Xylose Fermentation in Saccharomyces cerevisiae Due to Overexpression of Water-Forming NADH Oxidase

(2011) Guo-Chang Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Effect of endoxylanase and α-l-arabinofuranosidase supplementation on the enzymatic hydrolysis of steam exploded wheat straw

(2011) P. Alvira et al.   BIORESOURCE TECHNOLOGY

Plasmid-mediate transfer of FLO1 into industrial Saccharomyces cerevisiae PE-2 strain creates a strain useful for repeat-batch fermentations involving flocculation–sedimentation

(2011) Daniel G. Gomes et al.   BIORESOURCE TECHNOLOGY

Identification of candidate genes for yeast engineering to improve bioethanol production in very high gravity and lignocellulosic biomass industrial fermentations

(2011) Francisco B Pereira et al.   Biotechnology for Biofuels

Regulation of Cell Wall Biogenesis inSaccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway

(2011) David E. Levin   GENETICS

The Response to Heat Shock and Oxidative Stress in Saccharomyces cerevisiae

(2011) K. A. Morano et al.   GENETICS

Robust industrial Saccharomyces cerevisiae strains for very high gravity bio-ethanol fermentations

(2011) Francisco B. Pereira et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Metabolomic Study of Interactive Effects of Phenol, Furfural, and Acetic Acid on Saccharomyces cerevisiae

(2011) Ming-Zhu Ding et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae

(2011) F. M. Roelants et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimization of low-cost medium for very high gravity ethanol fermentations by Saccharomyces cerevisiae using statistical experimental designs

(2010) Francisco B. Pereira et al.   BIORESOURCE TECHNOLOGY

Furfural induces reactive oxygen species accumulation and cellular damage in Saccharomyces cerevisiae

(2010) Sandra A Allen et al.   Biotechnology for Biofuels

Selection of Saccharomyces cerevisiae strains for efficient very high gravity bio-ethanol fermentation processes

(2010) Francisco B. Pereira et al.   BIOTECHNOLOGY LETTERS

Comparative transcriptome profiling analyses during the lag phase uncover YAP1, PDR1, PDR3, RPN4, and HSF1 as key regulatory genes in genomic adaptation to the lignocellulose derived inhibitor HMF for Saccharomyces cerevisiae

(2010) Menggen Ma et al.   BMC GENOMICS

Yap1 activation by H2O2 or thiol-reactive chemicals elicits distinct adaptive gene responses

(2010) Xiaoguang Ouyang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial degradation in acetic acid-induced yeast apoptosis: the role of Pep4 and the ADP/ATP carrier

(2010) Clara Pereira et al.   MOLECULAR MICROBIOLOGY

Weak Organic Acid Stress Triggers Hyperphosphorylation of the Yeast Zinc-Finger Transcription Factor War1 and Dampens Stress Adaptation

(2010) Ingrid E. Frohner et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Genomic Expression Program Involving the Haa1p-Regulon in Saccharomyces cerevisiae Response to Acetic Acid

(2010) Nuno P. Mira et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Comparative Proteomic Analysis of Tolerance and Adaptation of Ethanologenic Saccharomyces cerevisiae to Furfural, a Lignocellulosic Inhibitory Compound

(2009) F.-M. Lin et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Resistance of Saccharomyces cerevisiae to High Concentrations of Furfural Is Based on NADPH-Dependent Reduction by at Least Two Oxireductases

(2009) D. Heer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Identification of Saccharomyces cerevisiae Genes Involved in the Resistance to Phenolic Fermentation Inhibitors

(2009) Linda Sundström et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Production of pulp from Salix viminalis energy crops using the FIRSST process

(2009) Jean-Michel Lavoie et al.   BIORESOURCE TECHNOLOGY

Effects of acetic acid on the kinetics of xylose fermentation by an engineered, xylose-isomerase-basedSaccharomyces cerevisiaestrain

(2009) Eleonora Bellissimi et al.   FEMS YEAST RESEARCH

A novel NADPH-dependent aldehyde reductase gene from Saccharomyces cerevisiae NRRL Y-12632 involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion

(2009) Z. Lewis Liu et al.   GENE

Cell membrane damage induced by phenolic acids on wine lactic acid bacteria

(2009) F.M. Campos et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Experimental evaluation of alkaline treatment as a method for enhancing the enzymatic digestibility of autohydrolysedAcacia dealbata

(2009) Remedios Yáñez et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Overexpression of Saccharomyces cerevisiae transcription factor and multidrug resistance genes conveys enhanced resistance to lignocellulose-derived fermentation inhibitors

(2009) Björn Alriksson et al.   PROCESS BIOCHEMISTRY

Effect of trehalose on protein structure

(2009) Nishant Kumar Jain et al.   PROTEIN SCIENCE

Multiple gene-mediated NAD(P)H-dependent aldehyde reduction is a mechanism of in situ detoxification of furfural and 5-hydroxymethylfurfural by Saccharomyces cerevisiae

(2008) Z. Lewis Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Redox control and oxidative stress in yeast cells

(2008) Enrique Herrero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Weak Organic Acids Trigger Conformational Changes of the Yeast Transcription Factor War1in Vivoto Elicit Stress Adaptation

(2008) Christa Gregori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY