Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity
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Title
Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity
Authors
Keywords
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Journal
Wiley Interdisciplinary Reviews-Systems Biology and Medicine
Volume 5, Issue 4, Pages 461-480
Publisher
Wiley
Online
2013-06-04
DOI
10.1002/wsbm.1222
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Note: Only part of the references are listed.- Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?
- (2012) François Bouzom et al. BIOPHARMACEUTICS & DRUG DISPOSITION
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- (2012) C. Glenn Begley et al. NATURE
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- (2012) Karen E. Joyce et al. NEURAL NETWORKS
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- (2012) R. Iyengar et al. Science Translational Medicine
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- (2012) Sean HJ Kim et al. Theoretical Biology and Medical Modelling
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- (2011) Paul D. Grosman et al. ECOLOGICAL MODELLING
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- (2011) Andrea N Edginton et al. Expert Opinion on Drug Metabolism & Toxicology
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- Systems Pharmacology: Bridging Systems Biology and Pharmacokinetics-Pharmacodynamics (PKPD) in Drug Discovery and Development
- (2011) Piet H. van der Graaf et al. PHARMACEUTICAL RESEARCH
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- (2008) Antoon Goderis et al. Future Generation Computer Systems-The International Journal of eScience
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- Introducing Spatial Information into Predictive NF-κB Modelling – An Agent-Based Approach
- (2008) Mark Pogson et al. PLoS One
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- (2008) Gary An Theoretical Biology and Medical Modelling
- Symmetric competition causes population oscillations in an individual-based model of forest dynamics
- (2007) Paul Caplat et al. ECOLOGICAL MODELLING
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