Moving beyond in silico tools to in silico science in support of drug development research

A computational approach to resolve cell level contributions to early glandular epithelial cancer progression

(2010) Sean HJ Kim et al.   BMC Systems Biology

Simulation of lung alveolar epithelial wound healing in vitro

(2010) S. H. J. Kim et al.   Journal of the Royal Society Interface

Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity

(2010) Shahab Sheikh-Bahaei et al.   JOURNAL OF THEORETICAL BIOLOGY

Identifying the Rules of Engagement Enabling Leukocyte Rolling, Activation, and Adhesion

(2010) Jonathan Tang et al.   PLoS Computational Biology

Mechanistic Insight from In Silico Pharmacokinetic Experiments: Roles of P-glycoprotein, Cyp3A4 Enzymes, and Microenvironments

(2009) T. N. Lam et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

At the Biological Modeling and Simulation Frontier

(2009) C. Anthony Hunt et al.   PHARMACEUTICAL RESEARCH

A Computational Approach to Understand In Vitro Alveolar Morphogenesis

(2009) Sean H. J. Kim et al.   PLoS One

Computational investigation of epithelial cell dynamic phenotype in vitro

(2009) Sean HJ Kim et al.   Theoretical Biology and Medical Modelling

Essential operating principles for tumor spheroid growth

(2008) Jesse A Engelberg et al.   BMC Systems Biology

Computational Strategies Unravel and Trace How Liver Disease Changes Hepatic Drug Disposition

(2008) S. Park et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS