Model-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity

Sensitivity of Older Patients to Antipsychotic Motor Side Effects: A PET Study Examining Potential Mechanisms

(2009) Hiroyuki Uchida et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Quetiapine Extended-Release Versus Immediate-Release Formulation

(2009) David C. Mamo et al.   JOURNAL OF CLINICAL PSYCHIATRY

Monthly Administration of Long-Acting Injectable Risperidone and Striatal Dopamine D2 Receptor Occupancy for the Management of Schizophrenia

(2009) Hiroyuki Uchida et al.   JOURNAL OF CLINICAL PSYCHIATRY

Brain and Plasma Pharmacokinetics of Aripiprazole in Patients With Schizophrenia: An [18F]Fallypride PET Study

(2008) Gerhard Gründer et al.   AMERICAN JOURNAL OF PSYCHIATRY

Quantitative Disease, Drug, and Trial Models

(2008) Jogarao V.S. Gobburu et al.   Annual Review of Pharmacology and Toxicology

An Agonist–Antagonist Interaction Model for Prolactin Release Following Risperidone and Paliperidone Treatment

(2008) LE Friberg et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Dose–Response of Ritonavir on Hepatic CYP3A Activity and Elvitegravir Oral Exposure

(2008) AA Mathias et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Modelling placebo response in depression trials using a longitudinal model with informative dropout

(2008) Roberto Gomeni et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Using pharmacokinetic–pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics

(2008) Christina Kurre Olsen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pharmacokinetics and time-course of D2 receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients

(2008) AM Catafau et al.   JOURNAL OF PSYCHOPHARMACOLOGY

A review of the association between antipsychotic use and hyperprolactinaemia

(2008) Chris Bushe et al.   JOURNAL OF PSYCHOPHARMACOLOGY

What drives success for specialty pharmaceuticals?

(2008) Mark Gudiksen et al.   NATURE REVIEWS DRUG DISCOVERY

Dose–Occupancy Study of Striatal and Extrastriatal Dopamine D2 Receptors by Aripiprazole in Schizophrenia with PET and [18F]Fallypride

(2008) Lawrence S Kegeles et al.   NEUROPSYCHOPHARMACOLOGY

The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development

(2008) Dean F Wong et al.   NEUROPSYCHOPHARMACOLOGY

Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects

(2008) Katrin M. Kirschbaum et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Effects of aripiprazole/OPC-14597 on motor activity, pharmacological models of psychosis, and brain activity in rats

(2007) R.E. Nordquist et al.   NEUROPHARMACOLOGY