SorLA Complement-type Repeat Domains Protect the Amyloid Precursor Protein against Processing

Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease

(2013) T. E. Willnow et al.   JOURNAL OF CELL SCIENCE

Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein

(2013) C. Gustafsen et al.   JOURNAL OF NEUROSCIENCE

Protein Sorting Motifs in the Cytoplasmic Tail of SorCS1 Control Generation of Alzheimer's Amyloid-  Peptide

(2013) R. F. Lane et al.   JOURNAL OF NEUROSCIENCE

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

(2013) C Reitz et al.   Translational Psychiatry

Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

(2012) A. W. Fjorback et al.   JOURNAL OF NEUROSCIENCE

High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease

(2012) C Pottier et al.   MOLECULAR PSYCHIATRY

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

(2012) Akhil Bhalla et al.   NEUROBIOLOGY OF DISEASE

Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease

(2011) Christiane Reitz   ARCHIVES OF NEUROLOGY

Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate

(2011) Yi Xue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1

(2011) Rachel F Lane et al.   Molecular Neurodegeneration

Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid  -peptides in human cerebrospinal fluid

(2011) A. Halim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

(2010) Christiane Reitz et al.   ANNALS OF NEUROLOGY

The Novel Membrane Protein TMEM59 Modulates Complex Glycosylation, Cell Surface Expression, and Secretion of the Amyloid Precursor Protein

(2010) Sylvia Ullrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Minimal Interface Between ApoE and LRP

(2010) Miklos Guttman et al.   JOURNAL OF MOLECULAR BIOLOGY

Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-  Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex

(2010) R. F. Lane et al.   JOURNAL OF NEUROSCIENCE

Structural Basis for Specific Recognition of Reelin by Its Receptors

(2010) Norihisa Yasui et al.   STRUCTURE

Mode of Interaction between β2GPI and Lipoprotein Receptors Suggests Mutually Exclusive Binding of β2GPI to the Receptors and Anionic Phospholipids

(2010) Chang-Jin Lee et al.   STRUCTURE

Decoding of Lipoprotein−Receptor Interactions: Properties of Ligand Binding Modules Governing Interactions with Apolipoprotein E

(2009) Miklos Guttman et al.   BIOCHEMISTRY

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2

(2009) D. Kaden et al.   JOURNAL OF CELL SCIENCE

Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor

(2009) Sha Huang et al.   JOURNAL OF LIPID RESEARCH

Sensors and regulators of intracellular pH

(2009) Joseph R. Casey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of β-Secretase (BACE1) Substrates Using Quantitative Proteomics

(2009) Matthew L. Hemming et al.   PLoS One

Structural insights into recognition of β2-glycoprotein I by the lipoprotein receptors

(2009) Dmitri Beglov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Sortilin-related Receptor with A-type Repeats (SORLA) Affects the Amyloid Precursor Protein-dependent Stimulation of ERK Signaling and Adult Neurogenesis

(2008) Michael Rohe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease

(2008) S. E. Dodson et al.   JOURNAL OF NEUROSCIENCE

Elucidation of O-Glycosylation Structures of the β-Amyloid Precursor Protein by Liquid Chromatography−Mass Spectrometry Using Electron Transfer Dissociation and Collision Induced Dissociation

(2008) Irina Perdivara et al.   JOURNAL OF PROTEOME RESEARCH

Trafficking, a key player in regulated intramembrane proteolysis

(2008) Ragna Sannerud et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY