Squaramide-catalysed asymmetric cascade aza-Michael/Michael addition reaction for the synthesis of chiral trisubstituted pyrrolidines

Bifunctional Amine-Squaramides: Powerful Hydrogen-Bonding Organocatalysts for Asymmetric Domino/Cascade Reactions

(2015) Pankaj Chauhan et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Enantioselective Cascade Aza-Michael/Michael Addition Sequence for Asymmetric Synthesis of Chiral Spiro[pyrrolidine-3,3′-oxindole]s

(2015) Bo-Liang Zhao et al.   Asian Journal of Organic Chemistry

Chiral Fullerenes from Asymmetric Catalysis

(2014) Enrique E. Maroto et al.   ACCOUNTS OF CHEMICAL RESEARCH

PyBidine-Cu(OTf)2-Catalyzed Asymmetric [3+2] Cycloaddition with Imino Esters: Harmony of Cu-Lewis Acid and Imidazolidine-NH Hydrogen Bonding in Concerto Catalysis

(2014) Takayoshi Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-catalyzed dynamic systemic resolution of α-iminonitriles in a 1,3-dipolar cycloaddition process

(2014) Lei Hu et al.   CHEMICAL COMMUNICATIONS

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

(2014) Javier Adrio et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Construction of Polycyclic Spirooxindoles by Organocatalytic 1,3-Dipolar Cycloaddition of 2-Cyclohexenone Catalyzed by Proline-Sulfonamide

(2014) Jun-An Xiao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Control of the Dual Reactivity (Iminium-Dienamine) of β-Arylmethyl α,β-Unsaturated Aldehydes in Organocatalytic 1,3-Dipolar Cycloadditions with N-Benzoyl C,N-Cyclic Azomethine Imines

(2014) Cristina Izquierdo et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of α-Heteroarylpyrrolidines by Copper-Catalyzed 1,3-Dipolar Cycloaddition of α-Silylimines

(2014) Ana Pascual-Escudero et al.   ORGANIC LETTERS

Chiral phosphoric acid catalyzed 1,3-dipolar cycloadditions of aldehydes, diethyl α-aminomalonate, and nitroalkenes

(2014) Wenqiang Luo et al.   TETRAHEDRON-ASYMMETRY

Chiral diphenylperhydroindolinol silyl ether catalyzed domino oxa-Michael–aldol condensations for the asymmetric synthesis of benzopyrans

(2014) Ya-Hui Feng et al.   TETRAHEDRON-ASYMMETRY

Catalytic asymmetric conjugate addition of various α-mercaptoketones to α,β-unsaturated N-acylated oxazolidin-2-ones with bifunctional organocatalyst

(2014) Bo-Liang Zhao et al.   RSC Advances

Synthesis of Optically Active 2H-Thiopyrano[2,3-b]quinolines with Three Contiguous Stereocentersviaan Organocatalytic Asymmetric Tandem Michael-Henry Reaction

(2013) Lulu Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Enantioselective Cascade Aza-Michael/Michael Addition for the Synthesis of Highly Functionalized Tetrahydroquinolines and Tetrahydrochromanoquinolines

(2013) Wen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Asymmetric Synthesis of Tetracyclic Pyridocarbazole Derivatives by Using a Diels-Alder/aza-Michael/Aldol Condensation Domino Reaction

(2013) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of Chiral Pyrrolizine-Based Triheterocycles by Organocatalytic Cascade Aza-Michael-Aldol Reactions

(2013) Hyo-Jun Lee et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cinchona-Based Primary Amine-Catalyzed Asymmetric Cascade Aza-Michael–Aldol Reactions of Enones with 2-(1H-Pyrrol-2-yl)-2-oxoacetates: Synthesis of Chiral Pyrrolizines with Multistereocenters

(2013) Hyo-Jun Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Cascade Sulfa-Michael/Aldol Reaction of β,β-Disubstituted Enones: Enantioselective Synthesis of Tetrahydrothiophenes with a Trifluoromethylated Quaternary Center

(2013) Yu Su et al.   JOURNAL OF ORGANIC CHEMISTRY

What Controls Regiochemistry in 1,3-Dipolar Cycloadditions of Münchnones with Nitrostyrenes?

(2013) Justin M. Lopchuk et al.   ORGANIC LETTERS

Biomimetic Asymmetric 1,3-Dioplar Cycloaddition: Amino Acid Precursors in Biosynthesis Serve as Latent Azomethine Ylides

(2013) Chang Guo et al.   ORGANIC LETTERS

Organocatalytic Enantioselective Dipolar [3+2] Cycloadditions of Acetylenic Aldehydes with Nitrones for the Formation of Chiral 4-Isoxazolines

(2012) Xianrong Cai et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Synthesis of 4-Isoxazolines by 1,3-Dipolar Cycloadditions of Nitrones to Alkynals Catalyzed by Fluorodiphenylmethylpyrrolidines

(2012) José Alemán et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent Developments in Asymmetric Organocatalytic Domino Reactions

(2012) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

An Organocatalytic Cascade Approach toward Polysubstituted Quinolines and Chiral 1,4-Dihydroquinolines-Unanticipated Effect of N-Protecting Groups

(2012) Xinshuai Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of α-Quaternary Proline Derivatives by 1,3-Dipolar Cycloaddition of α-Silylimines

(2012) Jorge Hernández-Toribio et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu-catalyzed asymmetric [3+2] cycloaddition of α-iminoamides with activated olefins

(2012) María González-Esguevillas et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric domino sulfa-Michael–aldol reactions of 2-mercaptobenzaldehyde with α,β-unsaturated N-acylpyrazoles for the construction of thiochromane

(2012) Xiu-Qin Dong et al.   CHEMICAL COMMUNICATIONS

Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

(2012) Hui Qian et al.   CHEMICAL COMMUNICATIONS

Enantioselective Organocatalytic One-Pot Amination/aza-Michael/Aldol Condensation Reaction Sequence: Synthesis of 3-Pyrrolines with a Quaternary Stereocenter

(2012) Alaric Desmarchelier et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Amine-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides and α,β-Unsaturated Aldehydes: Applications and Mechanistic Implications

(2012) Silvia Reboredo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Scaffold-Inspired Enantioselective Synthesis of Biologically Important Spiro[pyrrolidin-3,2′-oxindoles] with Structural Diversity through Catalytic Isatin-Derived 1,3-Dipolar Cycloadditions

(2012) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Organo-SOMO Cycloadditions: A Catalytic Approach to Complex Pyrrolidines from Olefins and Aldehydes

(2012) Nathan T. Jui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Asymmetric Synthesis of Enantiopure Dihydro-1,2-oxazines: Dual-Organocatalyst-Promoted Asymmetric Cascade Reaction

(2012) Hua Lin et al.   ORGANIC LETTERS

Silver/ThioClickFerrophos-Catalyzed Enantioselective Conjugate Addition and Cycloaddition of Glycine Imino Ester with Nitroalkenes

(2012) Kazumi Imae et al.   ORGANIC LETTERS

Organocatalytic asymmetric synthesis of trisubstituted pyrrolidines via a cascade reaction

(2012) Artur Noole et al.   TETRAHEDRON-ASYMMETRY

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Organocatalytic Enantioselective Michael-Addition of Malonic Acid Half-Thioesters to β-Nitroolefins: From Mimicry of Polyketide Synthases to Scalable Synthesis of γ-Amino Acids

(2011) Han Yong Bae et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes

(2011) Wen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

Dynamic One-Pot Three-Component Catalytic Asymmetric Transformation by Combination of Hydrogen-Bond-Donating and Amine Catalysts

(2011) Shuangzheng Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Simple Recipe for Sophisticated Cocktails: Organocatalytic One-Pot Reactions-Concept, Nomenclature, and Future Perspectives

(2011) Łukasz Albrecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

(2011) Javier Adrio et al.   CHEMICAL COMMUNICATIONS

Organocatalytic enantioselective synthesis of 2,3-dihydropyridazines

(2011) Maitane Fernández et al.   CHEMICAL COMMUNICATIONS

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Squaramides: physical properties, synthesis and applications

(2011) R. Ian Storer et al.   CHEMICAL SOCIETY REVIEWS

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pyrrolinone–Pyrrolidine Oligomers as Universal Peptidomimetics

(2011) Arjun Raghuraman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design, Synthesis, and Validation of a β-Turn Mimetic Library Targeting Protein–Protein and Peptide–Receptor Interactions

(2011) Landon R. Whitby et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Binaphthol-Derived Bisphosphoric Acids Serve as Efficient Organocatalysts for Highly Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides to Electron-Deficient Olefins

(2011) Long He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A

(2011) Mou-Nuo Cheng et al.   ORGANIC LETTERS

Binding to the open conformation of HIV-1 protease

(2011) Katrina W. Lexa et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Enantioselective heterocyclic synthesis of spiro chromanone–thiochroman complexes catalyzed by a bifunctional indane catalyst

(2010) Yaojun Gao et al.   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric 1,3-Dipolar Cycloaddition of α-Iminonitriles

(2010) Rocío Robles-Machín et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Silver Amide-Catalyzed Enantioselective [3 + 2] Cycloaddition of α-Aminophosphonates with Olefins

(2010) Yasuhiro Yamashita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in the Development of MMPIs and APNIs Based on the Pyrrolidine Platforms

(2010) X. Li et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Highly Enantioselective Michael Addition of Nitroalkanes to Chalcones Using Chiral Squaramides as Hydrogen Bonding Organocatalysts

(2010) Wen Yang et al.   ORGANIC LETTERS

N-(2-Pyridylmethyl)imines as Azomethine Precursors in Catalytic Asymmetric [3 + 2] Cycloadditions

(2010) Silvia Padilla et al.   ORGANIC LETTERS

Kinetic Resolution of Racemic 2,3-Allenoates by Organocatalytic Asymmetric 1,3-Dipolar Cycloaddition

(2010) Jie Yu et al.   ORGANIC LETTERS

Domino reaction of arylaldehydes and 1-acetylcyclopropanecarboxamides: one-pot access to highly functionalized spiropiperidine-2,4-diones

(2010) Jing Liu et al.   TETRAHEDRON LETTERS

Enantioselective Organocatalytic Domino Oxa-Michael/Aldol/Hemiacetalization: Synthesis of Polysubstituted Furofuranes Containing Four Stereocenters

(2009) Efraím Reyes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Four-Component Quadruple Domino Reaction Initiated by Oxa-Michael Addition of Alcohols to Acrolein

(2009) Fang-Lin Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Domino Reactions

(2009) Andrea-Nekane Alba et al.   CURRENT ORGANIC CHEMISTRY

1,3-Dipolar cycloadditions: applications to the synthesis of antiviral agents

(2009) Carmen Nájera et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral amine/chiral acid as an excellent organocatalytic system for the enantioselective tandem oxa-Michael-aldol reaction

(2009) Shu-Ping Luo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Catalytic 1,3-Dipolar Cycloaddition Involving 2,3-Allenoate Dipolarophiles

(2009) Jie Yu et al.   ORGANIC LETTERS

A Novel Enantioselective Catalytic Tandem Oxa-Michael-Henry Reaction: One-Pot Organocatalytic Asymmetric Synthesis of 3-Nitro-2H-chromenes

(2008) Dan-Qian Xu et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly enantio- and diastereoselective organocatalytic cascade aza-Michael–Michael reactions: a direct method for the synthesis of trisubstituted chiral pyrrolidines

(2008) Hao Li et al.   CHEMICAL COMMUNICATIONS

One-Pot Catalytic Asymmetric Cascade Synthesis of Cycloheptane Derivatives

(2008) Jan Vesely et al.   CHEMISTRY-A EUROPEAN JOURNAL

Reaction Control in the Organocatalytic Asymmetric One-Pot, Three-Component Reaction of Aldehydes, Diethyl α-Aminomalonate and Nitroalkenes: Toward Diversity-Oriented Synthesis

(2008) Yan-Kai Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of anN-Acylpyrrolidine for Inhibition of HCV Polymerase

(2008) Armel A. Agbodjan et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Organocatalytic Three-Component 1,3-Dipolar Cycloaddition: Control of Stereochemistry via a Chiral Brønsted Acid Activated Dipole

(2008) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines

(2008) Xinhong Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides with α,β-Unsaturated Ketones

(2008) Jorge Hernández-Toribio et al.   ORGANIC LETTERS

Thiourea-catalyzed asymmetric formal [3+2] cycloaddition of azomethine ylides with nitroolefins

(2008) Jianwu Xie et al.   TETRAHEDRON LETTERS