Binding to the open conformation of HIV-1 protease

Fragment-Based Screen against HIV Protease

(2010) Alexander L. Perryman et al.   Chemical Biology & Drug Design

Darunavir

(2009) Kate McKeage et al.   DRUGS

Twenty-Six Years of Anti-HIV Drug Discovery: Where Do We Stand and Where Do We Go?

(2009) Youcef Mehellou et al.   JOURNAL OF MEDICINAL CHEMISTRY

A poke in the eye: Inhibiting HIV-1 protease through its flap-recognition pocket

(2008) Kelly L. Damm et al.   BIOPOLYMERS

Targeting the Open-Flap Conformation of HIV-1 Protease with Pyrrolidine-Based Inhibitors

(2008) Jark Böttcher et al.   ChemMedChem

Rapid structural fluctuations of the free HIV protease flaps in solution: Relationship to crystal structures and comparison with predictions of dynamics calculations

(2002) Darón I. Freedberg et al.   PROTEIN SCIENCE