Organocatalytic Enantioselective Cascade Aza-Michael/Michael Addition for the Synthesis of Highly Functionalized Tetrahydroquinolines and Tetrahydrochromanoquinolines

Synthesis of Optically Active 2H-Thiopyrano[2,3-b]quinolines with Three Contiguous Stereocentersviaan Organocatalytic Asymmetric Tandem Michael-Henry Reaction

(2013) Lulu Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Aza-Henry Reaction of Imines Bearing a Benzothiazole Moiety Catalyzed by aCinchona-Based Squaramide

(2013) Hai-Xiao He et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of Functionalized Tetrahydronaphthalenesviaan Organocatalytic Nitroalkane-Michael/Henry Domino Reaction

(2013) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic asymmetric multicomponent cascade reaction via 1,3-proton shift and [3+2] cycloaddition: an efficient strategy for the synthesis of oxindole derivatives

(2013) Li Tian et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Organocatalytic Michael Addition/Cyclization Cascade Reaction of Ylideneoxindoles with Isothiocyanato Oxindoles: A Formal [3+2] Cycloaddition Approach to Optically Active Bispirooxindole Derivatives

(2013) Fen Tan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Squaramide–Tertiary Amine Catalyzed Asymmetric Cascade Sulfa-Michael/Michael Addition via Dynamic Kinetic Resolution: Access to Highly Functionalized Chromans with Three Contiguous Stereocenters

(2013) Wen Yang et al.   ORGANIC LETTERS

Recent Developments in Asymmetric Organocatalytic Domino Reactions

(2012) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives

(2012) Shu-Wen Duan et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Aza-Michael-Michael Cascade Reactions: A Flexible Approach to 2,3,4-Trisubstituted Tetrahydroquinolines

(2012) Zhen-Xin Jia et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Organocatalytic Cascade Strategy for the Enantioselective Construction of Spirocyclopentane Bioxindoles Containing Three Contiguous Stereocenters and Two Spiro Quaternary Centers

(2012) Wangsheng Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Quadruple Domino Organocatalysis: An Asymmetric Aza-Michael/Michael/Michael/Aldol Reaction Sequence Leading to Tetracyclic Indole Structures with Six Stereocenters

(2012) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Assembly of Functionalized Tetrahydroquinolines with Creation of an All-Carbon Quaternary Center

(2012) Hao Rui Tan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bifuctional Amino-Squaramides Catalyzed Asymmetric Spiroannulation Cascades with Aliphatic β,γ-Unsaturated α-Keto Esters: Controlling an Aldehyde Enolate

(2012) Xiaoqin Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Squaramide-catalysed enantio- and diastereoselective sulfa-Michael addition of thioacetic acid to α,β-disubstituted nitroalkenes

(2012) Wen Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Hydrogen-Bond-Mediated Cascade Reaction Involving Chalcones: Facile Synthesis of Enantioenriched Trisubstituted Tetrahydrothiophenes

(2012) Jun-Bing Ling et al.   ORGANIC LETTERS

Asymmetric synthesis of highly functionalized γ-lactams through an organocatalytic aza-Michael–Michael reaction cascade using fumaric acid amide esters as multi-reactive substrates

(2012) Takuya Yokosaka et al.   TETRAHEDRON LETTERS

Squaramide-catalyzed diastereo- and enantioselective Michael addition of 3-substituted oxindoles to nitroalkenes

(2012) Wen Yang et al.   TETRAHEDRON-ASYMMETRY

Organocatalytic Enantioselective Michael-Addition of Malonic Acid Half-Thioesters to β-Nitroolefins: From Mimicry of Polyketide Synthases to Scalable Synthesis of γ-Amino Acids

(2011) Han Yong Bae et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes

(2011) Wen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

C3-Symmetrical Cinchonine-Squaramide as New Highly Efficient, and Recyclable Organocatalyst for Enantioselective Michael Addition

(2011) Chang Min et al.   ADVANCED SYNTHESIS & CATALYSIS

Step-Economical Synthesis of Tetrahydroquinolines by Asymmetric Relay Catalytic Friedländer Condensation/Transfer Hydrogenation

(2011) Lei Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral squaramide-catalyzed highly diastereo- and enantioselective direct Michael addition of nitroalkanes to nitroalkenes

(2011) Wen Yang et al.   CHEMICAL COMMUNICATIONS

Advances in the Chemistry of Tetrahydroquinolines

(2011) Vellaisamy Sridharan et al.   CHEMICAL REVIEWS

Squaramides: physical properties, synthesis and applications

(2011) R. Ian Storer et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Synthesis of Tetrahydroquinolines with Quaternary Stereocenters through the Povarov Reaction

(2011) Mingsheng Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Enecarbamates as Dienophiles: Highly Diastereo- and Enantioselective Synthesis of Substituted 4-Aminotetrahydroquinolines

(2011) Guillaume Dagousset et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Activation of Enantiotopic C(sp3)−Hydrogen by Means of Chiral Phosphoric Acid: Asymmetric Synthesis of Tetrahydroquinoline Derivatives

(2011) Keiji Mori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Squaramide-catalyzed enantioselective Michael addition of malononitrile to chalcones

(2011) Wen Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Asymmetric Aza-Michael−Michael Addition Cascade: Enantioselective Synthesis of Polysubstituted 4-Aminobenzopyrans

(2011) Xu-Fan Wang et al.   ORGANIC LETTERS

Highly Enantioselective Synthesis of Polysubstituted TetrahydroquinolinesviaOrganocatalytic Michael/Aza-Henry Tandem Reactions

(2011) Zhen-Xin Jia et al.   ORGANIC LETTERS

Asymmetric Three-Component Inverse Electron-Demand Aza-Diels-Alder Reaction: Efficient Synthesis of Ring-Fused Tetrahydroquinolines

(2010) Mingsheng Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of new cis-fused tetrahydrochromeno[4,3-b]quinolines and their antiproliferative activity studies against MDA-MB-231 and MCF-7 breast cancer cell lines

(2010) K. Nagaiah et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Squaramide-catalyzed enantioselective Friedel–Crafts reaction of indoles with imines

(2010) Yong Qian et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric direct vinylogous aldol reactions of γ-crotonolactone with aromatic aldehydes

(2010) Sunil V. Pansare et al.   CHEMICAL COMMUNICATIONS

Quinaphos and Dihydro-Quinaphos Phosphine-Phosphoramidite Ligands for Asymmetric Hydrogenation

(2010) Thomas Pullmann et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Squaramides as Highly Enantioselective Catalysts for Michael Addition Reactions of 4-Hydroxycoumarins and 4-Hydroxypyrone to β,γ-Unsaturated α-Keto Esters

(2010) Dan-Qian Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Organocatalytic C−H Bond Functionalization via Tandem 1,5-Hydride Transfer/Ring Closure: Asymmetric Synthesis of Tetrahydroquinolines

(2010) Young Ku Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Highly Enantioselective Michael Addition of Nitroalkanes to Chalcones Using Chiral Squaramides as Hydrogen Bonding Organocatalysts

(2010) Wen Yang et al.   ORGANIC LETTERS

Enantioselective α-Amination of 1,3-Dicarbonyl Compounds Using Squaramide Derivatives as Hydrogen Bonding Catalysts

(2010) Hideyuki Konishi et al.   ORGANIC LETTERS

One-pot synthesis of the naturally occurring dimeric carbazole alkaloid murranimbine and its analogue

(2010) Mumu Chakraborty et al.   TETRAHEDRON LETTERS

Squaramide-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroalkenes

(2009) Ye Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Intramolecular Hydroarylations of ω-Aryloxy- and Arylamino-Tethered α,β-Unsaturated Aldehydes

(2009) Hai-Hua Lu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Domino Reactions

(2009) Andrea-Nekane Alba et al.   CURRENT ORGANIC CHEMISTRY

Chiral Brønsted Acid-Catalyzed Enantioselective Three-Component Povarov Reaction

(2009) Hua Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Consecutive Intramolecular Hydroamination/Asymmetric Transfer Hydrogenation under Relay Catalysis of an Achiral Gold Complex/Chiral Brønsted Acid Binary System

(2009) Zhi-Yong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Development of Double Axially Chiral Phosphoric Acids and Their Catalytic Transfer Hydrogenation of Quinolines

(2008) Qun-Sheng Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantio- and diastereoselective organocatalytic cascade aza-Michael–Michael reactions: a direct method for the synthesis of trisubstituted chiral pyrrolidines

(2008) Hao Li et al.   CHEMICAL COMMUNICATIONS

Ruthenium-Catalyzed Enantioselective Carbon−Carbon Bond Forming Reaction via Allenylidene-Ene Process: Synthetic Approach to Chiral Heterocycles Such As Chromane, Thiochromane, and 1,2,3,4-Tetrahydroquinoline Derivatives

(2008) Koji Fukamizu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cycloadditions of Palladium-Polarized Aza-o-xylylenes

(2008) Chao Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

(2008) Jeremiah P. Malerich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalysis: asymmetric cascade reactions catalysed by chiral secondary amines

(2008) Xinhong Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY