Catalytic asymmetric conjugate addition of various α-mercaptoketones to α,β-unsaturated N-acylated oxazolidin-2-ones with bifunctional organocatalyst

Enantioselective synthesis of enol lactones from tandem Michael addition/lactonization catalyzed by a chiral squaramide catalyst

(2014) Bo-Liang Zhao et al.   TETRAHEDRON-ASYMMETRY

Synthesis of Optically Active 2H-Thiopyrano[2,3-b]quinolines with Three Contiguous Stereocentersviaan Organocatalytic Asymmetric Tandem Michael-Henry Reaction

(2013) Lulu Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Enantioselective Cascade Aza-Michael/Michael Addition for the Synthesis of Highly Functionalized Tetrahydroquinolines and Tetrahydrochromanoquinolines

(2013) Wen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Aza-Henry Reaction of Imines Bearing a Benzothiazole Moiety Catalyzed by aCinchona-Based Squaramide

(2013) Hai-Xiao He et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective synthesis of α-nitro-δ-ketosulfones via a quinine–squaramide catalyzed conjugate addition of α-nitrosulfones to enones

(2013) Kalisankar Bera et al.   CHEMICAL COMMUNICATIONS

Cinchona-based squaramide-catalysed cascade aza-Michael–Michael addition: enantioselective construction of functionalized spirooxindole tetrahydroquinolines

(2013) Wen Yang et al.   CHEMICAL COMMUNICATIONS

Asymmetric synthesis of trans-dihydroarylfurans in a Friedel–Crafts/substitution domino reaction under squaramide catalysis

(2013) Carlos Jarava-Barrera et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Cascade Sulfa-Michael/Aldol Reaction of β,β-Disubstituted Enones: Enantioselective Synthesis of Tetrahydrothiophenes with a Trifluoromethylated Quaternary Center

(2013) Yu Su et al.   JOURNAL OF ORGANIC CHEMISTRY

Cinchona Alkaloid Squaramide Catalyzed Enantioselective Hydrazination/Cyclization Cascade Reaction of α-Isocyanoacetates and Azodicarboxylates: Synthesis of Optically Active 1,2,4-Triazolines

(2013) Mei-Xin Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Squaramide-Catalyzed Enantioselective Michael Addition of Masked Acyl Cyanides to Substituted Enones

(2013) Kin S. Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral squaramide-catalysed one-pot enantioselective sulfa-Michael addition/thioesterification of thiols with α,β-unsaturated N-acylated succinimides

(2013) Bo-Liang Zhao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Squaramide–Tertiary Amine Catalyzed Asymmetric Cascade Sulfa-Michael/Michael Addition via Dynamic Kinetic Resolution: Access to Highly Functionalized Chromans with Three Contiguous Stereocenters

(2013) Wen Yang et al.   ORGANIC LETTERS

Highly Efficient Catalytic Asymmetric Sulfa-Michael Addition of Thiols to trans-4,4,4-Trifluorocrotonoylpyrazole

(2012) Xiu-Qin Dong et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic asymmetric domino sulfa-Michael–aldol reactions of 2-mercaptobenzaldehyde with α,β-unsaturated N-acylpyrazoles for the construction of thiochromane

(2012) Xiu-Qin Dong et al.   CHEMICAL COMMUNICATIONS

An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives

(2012) Shu-Wen Duan et al.   CHEMICAL COMMUNICATIONS

Applications of asymmetric organocatalysis in medicinal chemistry

(2012) José Alemán et al.   CHEMICAL SOCIETY REVIEWS

Squaramide-catalysed enantio- and diastereoselective sulfa-Michael addition of thioacetic acid to α,β-disubstituted nitroalkenes

(2012) Wen Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Hydrogen-Bond-Mediated Cascade Reaction Involving Chalcones: Facile Synthesis of Enantioenriched Trisubstituted Tetrahydrothiophenes

(2012) Jun-Bing Ling et al.   ORGANIC LETTERS

An expedient approach to highly enantioenriched cyclic nitrones mediated by robust and recoverable C3-symmetric cinchonine-squaramide catalysts

(2012) Xin Han et al.   RSC Advances

Organocatalytic Enantioselective Michael-Addition of Malonic Acid Half-Thioesters to β-Nitroolefins: From Mimicry of Polyketide Synthases to Scalable Synthesis of γ-Amino Acids

(2011) Han Yong Bae et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes

(2011) Wen Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

C3-Symmetrical Cinchonine-Squaramide as New Highly Efficient, and Recyclable Organocatalyst for Enantioselective Michael Addition

(2011) Chang Min et al.   ADVANCED SYNTHESIS & CATALYSIS

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Squaramide-Catalyzed Enantioselective Conjugate Michael Addition of Various Thiols to α,β-Unsaturated N-Acylated Oxazolidin-2-ones

(2011) Le Dai et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Enolate Protonation in Sulfa–Michael Addition to α-SubstitutedN-Acryloyloxazolidin-2-ones with Bifunctional Organocatalyst

(2011) Nirmal K. Rana et al.   ORGANIC LETTERS

Highly Enantioselective Conjugate Addition of Thioglycolate to Chalcones Catalyzed by Lanthanum: Low Catalyst Loading and Remarkable Chiral Amplification

(2010) Yonghai Hui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric organocatalysis in total synthesis – a trial by fire

(2010) Eugenia Marqués-López et al.   NATURAL PRODUCT REPORTS

Highly Enantioselective Michael Addition of Nitroalkanes to Chalcones Using Chiral Squaramides as Hydrogen Bonding Organocatalysts

(2010) Wen Yang et al.   ORGANIC LETTERS

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

(2008) Jeremiah P. Malerich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Conjugate Addition of Simple Alkyl Thiols to α,β-UnsaturatedN-Acylated Oxazolidin-2-ones with Bifunctional Catalysts

(2008) Yan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric conjugate addition of thiols to (E)-3-crotonoyloxazolidin-2-one by iron or cobalt/pybox catalyst

(2008) Motoi Kawatsura et al.   TETRAHEDRON