“Sweet Flavonoids”: Glycosidase-Catalyzed Modifications

A novel Aspergillus oryzae diglycosidase that hydrolyzes 6-O-α-L-rhamnosyl-β-D-glucoside from flavonoids

(2018) Mai Ishikawa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bioavailability of Quercetin in Humans with a Focus on Interindividual Variation

(2018) A. Filipa Almeida et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Isoquercetin enzymatic production: A true story

(2018) Vladimír Křen et al.   Molecular Catalysis

Purification and characterization of a naringinase from a newly isolated strain of Bacillus amyloliquefaciens 11568 suitable for the transformation of flavonoids

(2017) Yunping Zhu et al.   FOOD CHEMISTRY

One-Pot Synthesis of Hyperoside by a Three-Enzyme Cascade Using a UDP-Galactose Regeneration System

(2017) Jianjun Pei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biochemical characterization of Aspergillus oryzae recombinant α- l -rhamnosidase expressed in Pichia pastoris

(2017) Mai Ishikawa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Exploiting the aglycon promiscuity of glycosyltransferase Bs-YjiC from Bacillus subtilis and its application in synthesis of glycosides

(2017) Longhai Dai et al.   JOURNAL OF BIOTECHNOLOGY

Potential of Icariin Metabolites from Epimedium koreanum Nakai as Antidiabetic Therapeutic Agents

(2017) Da Hye Kim et al.   MOLECULES

Quercetin and its analogues: optical and acido–basic properties

(2017) Michal Biler et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Simultaneous quantification of hyperin, reynoutrin and guaijaverin in mice plasma by LC-MS/MS: application to a pharmacokinetic study

(2016) Z. Li et al.   BIOMEDICAL CHROMATOGRAPHY

Effect of high hydrostatic pressure treatment on isoquercetin production from rutin by commercial α-l-rhamnosidase

(2016) Do-Yeon Kim et al.   BIOTECHNOLOGY LETTERS

Expression and biochemical characterization of recombinant α-l-rhamnosidase r-Rha1 from Aspergillus niger JMU-TS528

(2016) Lijun Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Recent progress in the enzymatic glycosylation of phenolic compounds

(2016) Lijuan Xu et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

RHA-P: Isolation, expression and characterization of a bacterial α- l -rhamnosidase from Novosphingobium sp. PP1Y

(2016) Federica De Lise et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Isoquercitrin production from rutin catalyzed by naringinase under ultrasound irradiation

(2016) Dan Zhu et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Synthesis of Derivatized Chitooligomers using Transglycosidases Engineered from the Fungal GH20 β-N -Acetylhexosaminidase

(2015) Kristýna Slámová et al.   ADVANCED SYNTHESIS & CATALYSIS

Bacteria as source of diglycosidase activity: Actinoplanes missouriensis produces 6-O-α-l-rhamnosyl-β-d-glucosidase active on flavonoids

(2015) Bárbara D. Neher et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Health-promoting effects of the citrus flavanone hesperidin

(2015) Chaoyun Li et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Dietary Flavonoid Aglycones and Their Glycosides: Which Show Better Biological Significance?

(2015) Jianbo Xiao   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Enzymatic Glycosylation of Phenolic Antioxidants: Phosphorylase-Mediated Synthesis and Characterization

(2015) Karel De Winter et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Metabolism of Rutin and Poncirin by Human Intestinal Microbiota and Cloning of Their Metabolizing ��-L-Rhamnosidase from Bifidobacterium dentium

(2015) Seo-Hyeon Bang et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Hydrolysis of the Rutinose-Conjugates Flavonoids Rutin and Hesperidin by the Gut Microbiota and Bifidobacteria

(2015) Alberto Amaretti et al.   Nutrients

Upscale of recombinant α-L-rhamnosidase production by Pichia pastoris MutS strain

(2015) Kristína Markošová et al.   Frontiers in Microbiology

An effective biphase system accelerates hesperidinase-catalyzed conversion of rutin to isoquercitrin

(2015) Jun Wang et al.   Scientific Reports

α-L-Rhamnosyl-β-D-glucosidase (Rutinosidase) fromAspergillus niger: Characterization and Synthetic Potential of a Novel Diglycosidase

(2014) Daniela Šimčíková et al.   ADVANCED SYNTHESIS & CATALYSIS

Advances in the biotechnological glycosylation of valuable flavonoids

(2014) Jianbo Xiao et al.   BIOTECHNOLOGY ADVANCES

Isoquercitrin: Pharmacology, toxicology, and metabolism

(2014) Kateřina Valentová et al.   FOOD AND CHEMICAL TOXICOLOGY

Substituent Effects on in Vitro Antioxidizing Properties, Stability, and Solubility in Flavonoids

(2014) Merichel Plaza et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

α-Rhamnosidase activity in the marine isolate Novosphingobium sp. PP1Y and its use in the bioconversion of flavonoids

(2014) Viviana Izzo et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Glycosynthases from Thermotoga neapolitana β-glucosidase 1A: A comparison of α-glucosyl fluoride and in situ-generated α-glycosyl formate donors

(2014) Tania Pozzo et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Preclinical Evidence for the Pharmacological Actions of Naringin: A Review

(2014) Saurabh Bharti et al.   PLANTA MEDICA

Regioselective synthesis of flavonoid bisglycosides using Escherichia coli harboring two glycosyltransferases

(2013) Hyeon Jeong Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Recombinant α-L-rhamnosidase ofAspergillus terreusimmobilization in polyvinylalcohol hydrogel and its application in rutin derhamnosylation

(2013) Martin Rebroš et al.   BIOCATALYSIS AND BIOTRANSFORMATION

Synthesis of Glycans and Glycopolymers Through Engineered Enzymes

(2013) Zachary Armstrong et al.   BIOPOLYMERS

Chemoenzymatic synthesis of α-l-rhamnosides using recombinant α-l-rhamnosidase from Aspergillus terreus

(2013) Karel De Winter et al.   BIORESOURCE TECHNOLOGY

Enzymatic glycosylation of multivalent scaffolds

(2013) Pavla Bojarová et al.   CHEMICAL SOCIETY REVIEWS

Recent development of phosphorylases possessing large potential for oligosaccharide synthesis

(2013) Hiroyuki Nakai et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A novel α-l-rhamnosidase with potential applications in citrus juice industry and in winemaking

(2013) Adriana E. Alvarenga et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Rutin: therapeutic potential and recent advances in drug delivery

(2013) Shrestha Sharma et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Enzymatic de-glycosylation of rutin improves its antioxidant and antiproliferative activities

(2013) Maria Elisa Melo Branco de Araújo et al.   FOOD CHEMISTRY

Production of Hesperetin Using a Covalently Multipoint Immobilized Diglycosidase from Acremonium sp. DSM24697

(2013) Lucrecia Piñuel et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

A sensitive LC–MS/MS method for simultaneous determination of six flavonoids in rat plasma: Application to a pharmacokinetic study of total flavonoids from mulberry leaves

(2013) Jun He et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

Chemistry and Biological Activities of Flavonoids: An Overview

(2013) Shashank Kumar et al.   TheScientificWorldJOURNAL

Aspergillus niger DLFCC-90 Rhamnoside Hydrolase, a New Type of Flavonoid Glycoside Hydrolase

(2012) Tingqiang Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Production of 3-O-xylosyl quercetin in Escherichia coli

(2012) Ramesh Prasad Pandey et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cell surface engineering of α-l-rhamnosidase for naringin hydrolysis

(2012) Qian Liu et al.   BIORESOURCE TECHNOLOGY

An efficient novel glycosylation of flavonoid by β-fructosidase resistant to hydrophilic organic solvents

(2012) Xueming Wu et al.   BIORESOURCE TECHNOLOGY

Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts

(2012) Tom Desmet et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enzymatic bioconversion of citrus hesperidin by Aspergillus sojae naringinase: Enhanced solubility of hesperetin-7-O-glucoside with in vitro inhibition of human intestinal maltase, HMG-CoA reductase, and growth of Helicobacter pylori

(2012) Young-Su Lee et al.   FOOD CHEMISTRY

Quantification of hesperidin in citrus-based foods using a fungal diglycosidase

(2012) Laura S. Mazzaferro et al.   FOOD CHEMISTRY

Elucidation of the Kinetic Behavior of Quercetin, Isoquercitrin, and Rutin Solubility by Physicochemical and Thermodynamic Investigations

(2012) Latifa Chebil et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Selective hydrolysis by commercially available hesperidinase for isoquercitrin production

(2012) Jun Wang et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Recombinant α-l-rhamnosidase from Aspergillus terreus in selective trimming of rutin

(2012) Daniela Gerstorferová et al.   PROCESS BIOCHEMISTRY

Charged Hexosaminides as New Substrates for β-N-Acetylhexosaminidase-Catalyzed Synthesis of Immunomodulatory Disaccharides

(2011) Pavla Bojarová et al.   ADVANCED SYNTHESIS & CATALYSIS

Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis

(2011) Stéphane Quideau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Naringinases: occurrence, characteristics, and applications

(2011) Maria H. Ribeiro   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The flavonoid quercetin in disease prevention and therapy: Facts and fancies

(2011) Maria Russo et al.   BIOCHEMICAL PHARMACOLOGY

Preparatory production of quercetin-3-β-d-glucopyranoside using alkali-tolerant thermostable α-l-rhamnosidase from Aspergillus terreus

(2011) Lenka Weignerová et al.   BIORESOURCE TECHNOLOGY

Quercetin production from rutin by a thermostable β-rutinosidase from Pyrococcus furiosus

(2011) Hyun-Koo Nam et al.   BIOTECHNOLOGY LETTERS

Transglycosylation specificity of Acremonium sp. α-rhamnosyl-β-glucosidase and its application to the synthesis of the new fluorogenic substrate 4-methylumbelliferyl-rutinoside

(2011) Laura S. Mazzaferro et al.   CARBOHYDRATE RESEARCH

Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short

(2011) Pavla Bojarová et al.   CHIMIA

A Sensitive LC–MS–MS Method for Simultaneous Quantification of Two Structural Isomers, Hyperoside and Isoquercitrin: Application to Pharmacokinetic Studies

(2011) Chunling Zhou et al.   CHROMATOGRAPHIA

Biosynthesis of (+)-catechin glycosides using recombinant amylosucrase from Deinococcus geothermalis DSM 11300

(2011) Hyun-Kug Cho et al.   ENZYME AND MICROBIAL TECHNOLOGY

Microwave Accelerated Transglycosylation of Rutin by Cyclodextrin Glucanotransferase from Bacillus sp. SK13.002

(2011) Tao Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

α-Rhamnosyl-β-glucosidase-Catalyzed Reactions for Analysis and Biotransformations of Plant-Based Foods

(2011) Marisol Minig et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Operational stabilization of fungal α-rhamnosyl-β-glucosidase by immobilization on chitosan composites

(2011) Lucrecia Piñuel et al.   PROCESS BIOCHEMISTRY

α-Oligoglucosylation of a sugar moiety enhances the bioavailability of quercetin glucosides in humans

(2010) Kaeko Murota et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Extracellular monoenzyme deglycosylation system of 7-O-linked flavonoid β-rutinosides and its disaccharide transglycosylation activity from Stilbella fimetaria

(2010) Laura Mazzaferro et al.   ARCHIVES OF MICROBIOLOGY

Enzyme-assisted extraction of flavonoids from Ginkgo biloba leaves: Improvement effect of flavonol transglycosylation catalyzed by Penicillium decumbens cellulase

(2010) Shuo Chen et al.   ENZYME AND MICROBIAL TECHNOLOGY

Identification and antioxidative properties of transglycosylated puerarins synthesised by an archaeal maltogenic amylase

(2010) Xiaolei Li et al.   FOOD CHEMISTRY

Purification and characterisation of Aspergillus sojae naringinase: The production of prunin exhibiting markedly enhanced solubility with in vitro inhibition of HMG-CoA reductase

(2010) Hye-Young Chang et al.   FOOD CHEMISTRY

4-Deoxy-substrates for β-N-acetylhexosaminidases: How to make use of their loose specificity

(2010) Kristýna Slámová et al.   GLYCOBIOLOGY

Improvement of activity and stability of soluble and sol–gel immobilized naringinase in co-solvent systems

(2010) Helder Vila-Real et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

α-l-Rhamnosidase: A review

(2010) Vinita Yadav et al.   PROCESS BIOCHEMISTRY

Enzymatically Modified Isoquercitrin, α-Oligoglucosyl Quercetin 3-O-Glucoside, Is Absorbed More Easily than Other Quercetin Glycosides or Aglycone after Oral Administration in Rats

(2009) Toshiaki Makino et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Preparation of icariside II from icariin by enzymatic hydrolysis method

(2009) Quan Xia et al.   FITOTERAPIA

One-step purification and immobilization of His-tagged rhamnosidase for naringin hydrolysis

(2009) Munish Puri et al.   PROCESS BIOCHEMISTRY

Probing the Aglycon Promiscuity of an Engineered Glycosyltransferase

(2008) Richard W. Gantt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic insights into glycosidase chemistry

(2008) David J Vocadlo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Influence of l-rhamnosyl-d-glucosyl derivatives on properties and biological interaction of flavonoids

(2008) Ersilia Bellocco et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glycosyltransferases: Structures, Functions, and Mechanisms

(2007) L.L. Lairson et al.   Annual Review of Biochemistry

HPLC analysis and pharmacokinetic study of quercitrin and isoquercitrin in rat plasma after administration ofHypericum japonicum thunb. extract

(2007) Juan Li et al.   BIOMEDICAL CHROMATOGRAPHY

N-Acetylhexosamine triad in one molecule: Chemoenzymatic introduction of 2-acetamido-2-deoxy-β-d-galactopyranosyluronic acid residue into a complex oligosaccharide

(2007) Pavla Bojarová et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC