Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise
出版年份 2022 全文链接
标题
Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise
作者
关键词
-
出版物
FEBS Journal
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2022-01-08
DOI
10.1111/febs.16344
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Restoring metabolism of myeloid cells reverses cognitive decline in ageing
- (2021) Paras S. Minhas et al. NATURE
- Blood–Brain Barrier Dynamics to Maintain Brain Homeostasis
- (2021) Marta Segarra et al. TRENDS IN NEUROSCIENCES
- ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism
- (2021) Guoyuan Qi et al. Cell Reports
- Accumulation of Cerebrospinal Fluid Glycerophospholipids and Sphingolipids in Cognitively Healthy Participants With Alzheimer’s Biomarkers Precedes Lipolysis in the Dementia Stage
- (2021) Alfred N. Fonteh et al. Frontiers in Neuroscience
- APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia
- (2021) Grzegorz Sienski et al. Science Translational Medicine
- Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
- (2021) Shaowei Wang et al. Molecular Neurodegeneration
- How the brain fights fatty acids’ toxicity
- (2021) Peter Schönfeld et al. NEUROCHEMISTRY INTERNATIONAL
- Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
- (2021) Raja Bhattacharyya et al. Cell Reports
- Alzheimer disease
- (2021) David S. Knopman et al. Nature Reviews Disease Primers
- Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model
- (2021) Sandra I. Mota et al. ARCHIVES OF TOXICOLOGY
- Diabetes mellitus contributes to higher cerebrospinal fluid tau levels selectively in Alzheimer's disease patients with the APOE4 genotype
- (2021) Caterina Motta et al. EUROPEAN JOURNAL OF NEUROLOGY
- Lipid droplets in the nervous system
- (2021) Isha Ralhan et al. JOURNAL OF CELL BIOLOGY
- TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination
- (2021) Garyfallia Gouna et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A contentious FDA ruling for Alzheimer's disease
- (2021) The Lancet Neurology LANCET NEUROLOGY
- Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial
- (2021) Daniel K Burns et al. LANCET NEUROLOGY
- Cholesterol and Alzheimer’s Disease; From Risk Genes to Pathological Effects
- (2021) Femke M. Feringa et al. Frontiers in Aging Neuroscience
- Neurotoxic reactive astrocytes induce cell death via saturated lipids
- (2021) Kevin A. Guttenplan et al. NATURE
- Aβ–ganglioside interactions in the pathogenesis of Alzheimer's disease
- (2020) Katsumi Matsuzaki BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Receptors for pro‐resolving mediators are increased in Alzheimer's disease brain
- (2020) Ceren Emre et al. BRAIN PATHOLOGY
- Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
- (2020) Julia Marschallinger et al. NATURE NEUROSCIENCE
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
- (2020) Eric M. Reiman et al. Nature Communications
- Cellular Specificity and Inter-cellular Coordination in the Brain Bioenergetic System: Implications for Aging and Neurodegeneration
- (2020) Guoyuan Qi et al. Frontiers in Physiology
- Polyunsaturated Fatty Acid Composition of Cerebrospinal Fluid Fractions Shows Their Contribution to Cognitive Resilience of a Pre-symptomatic Alzheimer’s Disease Cohort
- (2020) Alfred N. Fonteh et al. Frontiers in Physiology
- Mitochondria-Targeted Therapeutics for Alzheimer's Disease: The Good, the Bad, the Potential
- (2020) Yashi Mi et al. ANTIOXIDANTS & REDOX SIGNALING
- Midlife Chronological and Endocrinological Transitions in Brain Metabolism: System Biology Basis for Increased Alzheimer’s Risk in Female Brain
- (2020) Yiwei Wang et al. Scientific Reports
- Longitudinal trajectories of Alzheimer’s ATN biomarkers in elderly persons without dementia
- (2020) Meng-Shan Tan et al. Alzheimers Research & Therapy
- Higher risk of dementia in English older individuals who are overweight or obese
- (2020) Yixuan Ma et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
- (2020) Gill Livingston et al. LANCET
- Brain insulin resistance in Alzheimer's disease and related disorders: mechanisms and therapeutic approaches
- (2020) Derek Kellar et al. LANCET NEUROLOGY
- Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
- (2020) Stephen C. Cunnane et al. NATURE REVIEWS DRUG DISCOVERY
- Lipid Droplets in Neurodegenerative Disorders
- (2020) Brandon C. Farmer et al. Frontiers in Neuroscience
- Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism
- (2020) Esteban Gutierrez et al. Life Science Alliance
- ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease
- (2020) Maria Fe Lanfranco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The search for Alzheimer disease therapeutics — same targets, better trials?
- (2020) Michael S. Rafii et al. Nature Reviews Neurology
- CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease
- (2020) Gamze Ates et al. Redox Biology
- Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
- (2020) Fangda Leng et al. Nature Reviews Neurology
- Oxysterols and nuclear receptors
- (2019) Liqian Ma et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Apolipoprotein E4 Alters Astrocyte Fatty Acid Metabolism and Lipid Droplet Formation
- (2019) Brandon Farmer et al. Cells
- ApoE attenuates unresolvable inflammation by complex formation with activated C1q
- (2019) Changjun Yin et al. NATURE MEDICINE
- Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits
- (2019) Lien Beckers et al. Journal of Neuroinflammation
- Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model
- (2019) Rongcan Luo et al. Autophagy
- The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics
- (2019) Arne De Roeck et al. ACTA NEUROPATHOLOGICA
- Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease
- (2019) Nicholas F. Fitz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease
- (2019) Dawling A. Dionisio-Santos et al. Journal of Neuroinflammation
- Palmitic Acid-Induced NAD+ Depletion is Associated with the Reduced Function of SIRT1 and Increased Expression of BACE1 in Hippocampal Neurons
- (2019) Manuel Flores-León et al. NEUROCHEMICAL RESEARCH
- Lowering of Amyloid-Beta by β-Secretase Inhibitors — Some Informative Failures
- (2019) David S. Knopman NEW ENGLAND JOURNAL OF MEDICINE
- CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
- (2019) Penelope Dimas et al. eLife
- Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype
- (2019) Lisa Vermunt et al. Alzheimers & Dementia
- CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice
- (2019) Alexey M. Petrov et al. Neurotherapeutics
- Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms
- (2019) Huajun Yang et al. Frontiers in Neurology
- Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia
- (2019) Keenan A. Walker et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population
- (2019) Silvan Licher et al. NATURE MEDICINE
- Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
- (2019) Caroline Fecher et al. NATURE NEUROSCIENCE
- Modified Ketogenic Diet Is Associated With Improved Cerebrospinal Fluid Biomarker Profile, Cerebral Perfusion, And Cerebral Ketone Body Uptake In Older Adults At-Risk For Alzheimer’s Disease: A Pilot Study
- (2019) Bryan J. Neth et al. NEUROBIOLOGY OF AGING
- Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study
- (2019) Séverine Sabia et al. BMJ-British Medical Journal
- Elevated serum TC and LDL-C levels in Alzheimer’s disease and mild cognitive impairment: A meta-analysis study
- (2019) Yang Liu et al. BRAIN RESEARCH
- Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
- (2019) Justin M. Long et al. CELL
- Lipid rafts in glial cells: Role in neuroinflammation and pain processing
- (2019) Yury I. Miller et al. JOURNAL OF LIPID RESEARCH
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization
- (2018) Yunjie Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension
- (2018) Jessica G Abell et al. EUROPEAN HEART JOURNAL
- Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease
- (2018) Alpdogan Kantarci et al. EXPERIMENTAL NEUROLOGY
- GSEA of mouse and human mitochondriomes reveals fatty acid oxidation in astrocytes
- (2018) Abel Eraso-Pichot et al. GLIA
- Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease
- (2018) Russell H. Swerdlow JOURNAL OF ALZHEIMERS DISEASE
- Decreased content, rate of synthesis and export of cholesterol in the brain of apoE knockout mice
- (2018) Valéria Sutti Nunes et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes
- (2018) Lauren K. Fong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation
- (2018) Fan Liao et al. JOURNAL OF CLINICAL INVESTIGATION
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector
- (2018) Chengzhong Wang et al. NATURE MEDICINE
- Intermittent metabolic switching, neuroplasticity and brain health
- (2018) Mark P. Mattson et al. NATURE REVIEWS NEUROSCIENCE
- Alterations in cholesterol metabolism–related genes in sporadic Alzheimer's disease
- (2018) Cynthia Picard et al. NEUROBIOLOGY OF AGING
- Midlife insulin resistance,APOEgenotype, and late-life brain amyloid accumulation
- (2018) Laura L. Ekblad et al. NEUROLOGY
- A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease
- (2018) Estela Area-Gomez et al. Cell Death & Disease
- NSAID Exposure and Risk of Alzheimer's Disease: An Updated Meta-Analysis From Cohort Studies
- (2018) Caixia Zhang et al. Frontiers in Aging Neuroscience
- Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease
- (2018) Timothy J. Tracey et al. Frontiers in Molecular Neuroscience
- The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms
- (2018) Bob G. Schultz et al. Translational Neurodegeneration
- White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes
- (2018) Sara E. Nasrabady et al. Acta Neuropathologica Communications
- Alzheimer's disease and Type 2 Diabetes mellitus are distinct diseases with potential overlapping metabolic dysfunction upstream of observed cognitive decline
- (2018) Yevgen Chornenkyy et al. BRAIN PATHOLOGY
- Plasma and Brain Fatty Acid Profiles in Mild Cognitive Impairment and Alzheimer's Disease
- (2018) Stephen C. Cunnane et al. JOURNAL OF ALZHEIMERS DISEASE
- Increased Ceramide in Brains with Alzheimer's and Other Neurodegenerative Diseases
- (2018) Valery Filippov et al. JOURNAL OF ALZHEIMERS DISEASE
- Peroxisome Proliferators Reduce Spatial Memory Impairment, Synaptic Failure, and Neurodegeneration in Brains of a Double Transgenic Mice Model of Alzheimer's Disease
- (2018) Nibaldo C. Inestrosa et al. JOURNAL OF ALZHEIMERS DISEASE
- Restoration of Lipoxin A4 Signaling Reduces Alzheimer's Disease-Like Pathology in the 3xTg-AD Mouse Model
- (2018) Haley C. Dunn et al. JOURNAL OF ALZHEIMERS DISEASE
- Decreased Cerebrospinal Fluid Levels of L-Carnitine in Non-Apolipoprotein E4 Carriers at Early Stages of Alzheimer's Disease
- (2018) María Lodeiro et al. JOURNAL OF ALZHEIMERS DISEASE
- TREM2 — a key player in microglial biology and Alzheimer disease
- (2018) Tyler K. Ulland et al. Nature Reviews Neurology
- The sterol regulatory element-binding protein 2 is likely dysregulated by tau alterations in Alzheimer disease
- (2018) Chunyu Wang et al. BRAIN PATHOLOGY
- Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer’s disease
- (2018) Miho Ota et al. NEUROSCIENCE LETTERS
- Increased intermediate M1-M2 macrophage polarization and improved cognition in mild cognitive impairment patients on ω-3 supplementation
- (2017) Sam Famenini et al. FASEB JOURNAL
- APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes
- (2017) Jing Zhao et al. HUMAN MOLECULAR GENETICS
- Microglia in Alzheimer’s disease
- (2017) Heela Sarlus et al. JOURNAL OF CLINICAL INVESTIGATION
- Alzheimer’s disease: A matter of blood–brain barrier dysfunction?
- (2017) Axel Montagne et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer’s disease: a rationale for multi-nutrient dementia prevention
- (2017) Marcus O. W. Grimm et al. JOURNAL OF LIPID RESEARCH
- TREM2-Ligand Interactions in Health and Disease
- (2017) Daniel L. Kober et al. JOURNAL OF MOLECULAR BIOLOGY
- Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets
- (2017) Yijun Pan et al. JOURNAL OF NEUROCHEMISTRY
- TREM2 in Neurodegenerative Diseases
- (2017) Taylor R. Jay et al. Molecular Neurodegeneration
- SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology
- (2017) Hitoshi Shimano et al. Nature Reviews Endocrinology
- The mystery of membrane organization: composition, regulation and roles of lipid rafts
- (2017) Erdinc Sezgin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration
- (2017) Peter Schönfeld et al. NEUROCHEMISTRY INTERNATIONAL
- Effect of simvastatin on CSF Alzheimer disease biomarkers in cognitively normal adults
- (2017) Ge Li et al. NEUROLOGY
- Sex differences in Alzheimer risk
- (2017) Lisa Mosconi et al. NEUROLOGY
- Blood pressure from mid‐ to late life and risk of incident dementia
- (2017) Emer R. McGrath et al. NEUROLOGY
- Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism
- (2017) Heather A. Ferris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Medium-chain triglycerides given in the early stage of mild-to-moderate Alzheimer's disease enhance memory function
- (2017) Ayako Kimoto et al. Psychogeriatrics
- A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism
- (2017) Daniel Daugherty et al. Alzheimers Research & Therapy
- Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer’s disease
- (2017) Nophar Geifman et al. Alzheimers Research & Therapy
- Editorial: The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration
- (2017) Fei Yin et al. Frontiers in Aging Neuroscience
- Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain
- (2017) Ramasamy Thangavel et al. Frontiers in Aging Neuroscience
- Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases
- (2017) Gyun Jee Song et al. Frontiers in Aging Neuroscience
- Oligodendroglial myelination requires astrocyte-derived lipids
- (2017) Nutabi Camargo et al. PLOS BIOLOGY
- Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study
- (2017) Stuart G. Snowden et al. PLOS MEDICINE
- Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease
- (2017) Scott C. Neu et al. JAMA Neurology
- Medium-chain triglycerides given in the early stage of mild-to-moderate Alzheimer's disease enhance memory function
- (2017) Ayako Kimoto et al. Psychogeriatrics
- Impaired Resolution of Inflammation in Alzheimer’s Disease: A Review
- (2017) Robert A. Whittington et al. Frontiers in Immunology
- Altered Cholesterol Ester Cycle in Skin Fibroblasts from Patients with Alzheimer's Disease
- (2017) Alessandra Pani et al. JOURNAL OF ALZHEIMERS DISEASE
- Lipid Alterations in Lipid Rafts from Alzheimer's Disease Human Brain Cortex
- (2017) Virginia Martín et al. JOURNAL OF ALZHEIMERS DISEASE
- A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease
- (2017) Sofia Tzimopoulou et al. JOURNAL OF ALZHEIMERS DISEASE
- Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology
- (2016) Erin L. Abner et al. Alzheimers & Dementia
- White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network
- (2016) Seonjoo Lee et al. ANNALS OF NEUROLOGY
- Central Nervous System LipoproteinsHighlights
- (2016) Robert W. Mahley ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Eicosapentaenoic acid and docosahexaenoic acid increase the degradation of amyloid-β by affecting insulin-degrading enzyme
- (2016) Marcus O.W. Grimm et al. Biochemistry and Cell Biology
- Macrophage fatty acid oxidation and its roles in macrophage polarization and fatty acid-induced inflammation
- (2016) Dmitry Namgaladze et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lipid Raft Alterations in Aged-Associated Neuropathologies
- (2016) Raquel Marin et al. Current Alzheimer Research
- Identification and modification of amyloid-independent phenotypes of APOE4 mice
- (2016) Amanda M. DiBattista et al. EXPERIMENTAL NEUROLOGY
- Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes
- (2016) Paul S. Baxter et al. FREE RADICAL BIOLOGY AND MEDICINE
- Energy metabolism and inflammation in brain aging and Alzheimer’s disease
- (2016) Fei Yin et al. FREE RADICAL BIOLOGY AND MEDICINE
- ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies
- (2016) Anat Boehm-Cagan et al. JOURNAL OF ALZHEIMERS DISEASE
- Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice
- (2016) Kathryn E. Hopperton et al. Journal of Neuroinflammation
- Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid
- (2016) Nicolette Mary Heinsinger et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse
- (2016) Michael B. Dinkins et al. JOURNAL OF NEUROSCIENCE
- The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease
- (2016) Mounir Belkouch et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Identification and characterization of PPARα ligands in the hippocampus
- (2016) Avik Roy et al. Nature Chemical Biology
- Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects
- (2016) Domenico Ciavardelli et al. NEUROBIOLOGY OF AGING
- Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease
- (2016) Timothy A. Couttas et al. NEUROBIOLOGY OF AGING
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia
- (2016) Matthew P. Pase et al. STROKE
- Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer’s disease
- (2016) Jeffrey L. Cummings et al. Alzheimers Research & Therapy
- Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia
- (2016) Adriana Cristofano et al. PLoS One
- Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects
- (2015) Paul L. Wood et al. ACTA NEUROPSYCHIATRICA
- The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment
- (2015) Giuseppe Tosto et al. Alzheimers & Dementia
- Insulin resistance predicts brain amyloid deposition in late middle-aged adults
- (2015) Auriel A. Willette et al. Alzheimers & Dementia
- Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
- (2015) Liv Tybjærg Nordestgaard et al. Alzheimers & Dementia
- Intakes of fish and polyunsaturated fatty acids and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies1–3
- (2015) Yu Zhang et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mitochondria: The Cellular Hub of the Dynamic Coordinated Network
- (2015) Fei Yin et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications
- (2015) Carlotta Giorgi et al. ANTIOXIDANTS & REDOX SIGNALING
- Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzymatic activity through changes in oligomeric state
- (2015) P. Patrick Dotson et al. BIOCHEMICAL JOURNAL
- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study
- (2015) Renée FAG de Bruijn et al. BMC Medicine
- Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration
- (2015) Lucy Liu et al. CELL
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease
- (2015) Laura K. Hamilton et al. Cell Stem Cell
- Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics
- (2015) Angelika S. Rambold et al. DEVELOPMENTAL CELL
- ApoE4 upregulates the activity of mitochondria-associated ER membranes
- (2015) M. D. Tambini et al. EMBO REPORTS
- ω-3 Supplementation increases amyloid-β phagocytosis and resolvin D1 in patients with minor cognitive impairment
- (2015) Milan Fiala et al. FASEB JOURNAL
- ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease
- (2015) Yohei Shibuya et al. Future Medicinal Chemistry
- Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegenerationin vivo
- (2015) Mohammad A. Esmaeili et al. HUMAN MOLECULAR GENETICS
- Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease
- (2015) B. T. Casali et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial function in ageing: coordination with signalling and transcriptional pathways
- (2015) Fei Yin et al. JOURNAL OF PHYSIOLOGY-LONDON
- PPAR-α agonist regulates amyloid-β generation via inhibiting BACE-1 activity in human neuroblastoma SH-SY5Y cells transfected with APPswe gene
- (2015) Hua Zhang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis
- (2015) Mingqin Zhu et al. MOLECULAR NEUROBIOLOGY
- Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice
- (2015) Jin Hu et al. Molecular Neurodegeneration
- Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance
- (2015) Zhen Zhao et al. NATURE NEUROSCIENCE
- Perimenopause as a neurological transition state
- (2015) Roberta D. Brinton et al. Nature Reviews Endocrinology
- The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity
- (2015) Fei Yin et al. NEUROBIOLOGY OF AGING
- Oxidized Docosahexaenoic Acid Species and Lipid Peroxidation Products Increase Amyloidogenic Amyloid Precursor Protein Processing
- (2015) Marcus O.W. Grimm et al. Neurodegenerative Diseases
- Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and AβAccumulation
- (2015) Maja Jazvinšćak Jembrek et al. Oxidative Medicine and Cellular Longevity
- High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity
- (2015) Zhigang Liu et al. PLoS One
- Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP
- (2015) Grant T. Corbett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glial β-Oxidation regulates Drosophila Energy Metabolism
- (2015) Joachim G. Schulz et al. Scientific Reports
- Cholesterol metabolism and homeostasis in the brain
- (2015) Juan Zhang et al. Protein & Cell
- Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects
- (2015) Paul L. Wood et al. ACTA NEUROPSYCHIATRICA
- Alzheimer's disease
- (2015) Colin L. Masters et al. Nature Reviews Disease Primers
- White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease
- (2015) Lauren P. Klosinski et al. EBioMedicine
- Microspectroscopy (μFTIR) Reveals Co-localization of Lipid Oxidation and Amyloid Plaques in Human Alzheimer Disease Brains
- (2014) Núria Benseny-Cases et al. ANALYTICAL CHEMISTRY
- Myelination of the Nervous System: Mechanisms and Functions
- (2014) Klaus-Armin Nave et al. Annual Review of Cell and Developmental Biology
- Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease
- (2014) Raúl González-Domínguez et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses
- (2014) Dmitry Namgaladze et al. DIABETOLOGIA
- Myelination at a glance
- (2014) N. Snaidero et al. JOURNAL OF CELL SCIENCE
- Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease models
- (2014) Jenny U. Johansson et al. JOURNAL OF CLINICAL INVESTIGATION
- Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer’s disease
- (2014) Jong Kil Lee et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
- (2014) Yang Yu et al. JOURNAL OF NEURAL TRANSMISSION
- Tau Pathology Induces Intraneuronal Cholesterol Accumulation
- (2014) Frauke Glöckner et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Reversal of apoE4-Driven Brain Pathology and Behavioral Deficits by Bexarotene
- (2014) A. Boehm-Cagan et al. JOURNAL OF NEUROSCIENCE
- The Role of PICALM in Alzheimer’s Disease
- (2014) Wei Xu et al. MOLECULAR NEUROBIOLOGY
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
- (2014) Elysse M. Knight et al. NEUROBIOLOGY OF AGING
- Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer's disease and facilitates APP/BACE1 interactions
- (2014) Noemí Fabelo et al. NEUROBIOLOGY OF AGING
- Ceramides and sphingomyelinases in senile plaques
- (2014) Maï Panchal et al. NEUROBIOLOGY OF DISEASE
- Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
- (2014) Yadong Huang et al. NEUROBIOLOGY OF DISEASE
- ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?
- (2014) Takahisa Kanekiyo et al. NEURON
- Human Cerebrospinal Fluid Fatty Acid Levels Differ between Supernatant Fluid and Brain-Derived Nanoparticle Fractions, and Are Altered in Alzheimer's Disease
- (2014) Alfred N. Fonteh et al. PLoS One
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis
- (2014) Petroula Proitsi et al. PLOS MEDICINE
- Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease
- (2013) Julius Popp et al. BIOCHEMICAL PHARMACOLOGY
- MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond
- (2013) Jean E. Vance BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Amyloid precursor protein controls cholesterol turnover needed for neuronal activity
- (2013) Nathalie Pierrot et al. EMBO Molecular Medicine
- APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease
- (2013) Elisabet Barbero-Camps et al. HUMAN MOLECULAR GENETICS
- Diet-Induced Obesity Suppresses Expression of Many Proteins at the Blood–Brain Barrier
- (2013) Suidong Ouyang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis
- (2013) Hua Cheng et al. JOURNAL OF NEUROCHEMISTRY
- Palmitoylation of Amyloid Precursor Protein Regulates Amyloidogenic Processing in Lipid Rafts
- (2013) R. Bhattacharyya et al. JOURNAL OF NEUROSCIENCE
- Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease
- (2013) Yoko Tajima et al. Lipids in Health and Disease
- Acat1 Knockdown Gene Therapy Decreases Amyloid-β in a Mouse Model of Alzheimer's Disease
- (2013) Stephanie R Murphy et al. MOLECULAR THERAPY
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and Alzheimer's Mouse Brain: Implication for Bioenergetic Intervention
- (2013) Fan Ding et al. PLoS One
- ApoE influences amyloid- (A ) clearance despite minimal apoE/A association in physiological conditions
- (2013) P. B. Verghese et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Cyclic AMP Response Element Binding and Hippocampal Plasticity-Related Genes by Peroxisome Proliferator-Activated Receptor α
- (2013) Avik Roy et al. Cell Reports
- Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides
- (2013) Angela J. Hanson et al. JAMA Neurology
- Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions
- (2013) Geert Jan Biessels et al. Lancet Diabetes & Endocrinology
- Inflammatory prostaglandin E2signaling in a mouse model of Alzheimer disease
- (2012) Ju Shi et al. ANNALS OF NEUROLOGY
- Mitochondrial Thiols in the Regulation of Cell Death Pathways
- (2012) Fei Yin et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondrial Energy Metabolism and Redox Signaling in Brain Aging and Neurodegeneration
- (2012) Fei Yin et al. ANTIOXIDANTS & REDOX SIGNALING
- Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
- (2012) Estela Area-Gomez et al. EMBO JOURNAL
- Lipid Metabolism and Neuroinflammation in Alzheimer's Disease: A Role for Liver X Receptors
- (2012) Jihong Kang et al. ENDOCRINE REVIEWS
- Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain
- (2012) Rukhsana Sultana et al. FREE RADICAL BIOLOGY AND MEDICINE
- Small-Molecule Structure Correctors Target Abnormal Protein Structure and Function: Structure Corrector Rescue of Apolipoprotein E4–Associated Neuropathology
- (2012) Robert W. Mahley et al. JOURNAL OF MEDICINAL CHEMISTRY
- PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid- Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
- (2012) M. Yamanaka et al. JOURNAL OF NEUROSCIENCE
- Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease
- (2012) S. Mandrekar-Colucci et al. JOURNAL OF NEUROSCIENCE
- Lipid rafts, synaptic transmission and plasticity: Impact in age-related neurodegenerative diseases
- (2012) Ana M. Sebastião et al. NEUROPHARMACOLOGY
- Elevated cerebrospinal fluid sphingomyelin levels in prodromal Alzheimer's disease
- (2012) M. Kosicek et al. NEUROSCIENCE LETTERS
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Peroxisomal alterations in Alzheimer’s disease
- (2011) Jianqiu Kou et al. ACTA NEUROPATHOLOGICA
- Prostaglandins and Inflammation
- (2011) Emanuela Ricciotti et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Pharmacogenetic analysis of the effects of polymorphisms in APOE, IDE and IL1B on a ketone body based therapeutic on cognition in mild to moderate Alzheimer's disease; a randomized, double-blind, placebo-controlled study
- (2011) Samuel T Henderson et al. BMC Medical Genetics
- Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimers Disease: Two Phase 3 Studies
- (2011) C. Harrington et al. Current Alzheimer Research
- Impact and Therapeutic Potential of PPARs in Alzheimers Disease
- (2011) Michael T. Heneka et al. Current Neuropharmacology
- Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease
- (2011) Robin B. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms
- (2011) Marcus O. W. Grimm et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rosiglitazone Improves Spatial Memory and Decreases Insoluble Aβ1–42 in APP/PS1 Mice
- (2011) Julie-Ann O’Reilly et al. Journal of Neuroimmune Pharmacology
- Dietary Cholesterol and Its Effect on Tau Protein: A Study in Apolipoprotein E-Deficient and P301L Human Tau Mice
- (2011) Frauke Glöckner et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Structures, Biosynthesis, and Functions of Gangliosides-an Overview
- (2011) Robert K. Yu et al. Journal of Oleo Science
- Epidemiology of Alzheimer disease
- (2011) Christiane Reitz et al. Nature Reviews Neurology
- Linking lipids to Alzheimer's disease: cholesterol and beyond
- (2011) Gilbert Di Paolo et al. NATURE REVIEWS NEUROSCIENCE
- A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease
- (2011) M. Sano et al. NEUROLOGY
- Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies
- (2011) K. J. Anstey et al. Obesity Reviews
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- Higher Incidence of Mild Cognitive Impairment in Familial Hypercholesterolemia
- (2010) Daniel Zambón et al. AMERICAN JOURNAL OF MEDICINE
- PPARs: diverse regulators in energy metabolism and metabolic diseases
- (2010) Yong-Xu Wang CELL RESEARCH
- Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study
- (2010) Michael Gold et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease
- (2010) Joseph F. Quinn et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models
- (2010) Roman Chrast et al. JOURNAL OF LIPID RESEARCH
- Neuronal LRP1 Knockout in Adult Mice Leads to Impaired Brain Lipid Metabolism and Progressive, Age-Dependent Synapse Loss and Neurodegeneration
- (2010) Q. Liu et al. JOURNAL OF NEUROSCIENCE
- Age-Varying Association Between Statin Use and Incident Alzheimer's Disease
- (2010) Ge Li et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Wnt signaling activation reduces neuropathological markers in a mouse model of Alzheimer's disease
- (2010) E M Toledo et al. MOLECULAR PSYCHIATRY
- Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe
- (2010) H. H. Feldman et al. NEUROLOGY
- Brain fuel metabolism, aging, and Alzheimer’s disease
- (2010) Stephen Cunnane et al. NUTRITION
- ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
- (2010) E. Y. Bryleva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Apolipoprotein E: From lipid transport to neurobiology
- (2010) Paul S. Hauser et al. PROGRESS IN LIPID RESEARCH
- Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria
- (2009) Estela Area-Gomez et al. AMERICAN JOURNAL OF PATHOLOGY
- Acyl-CoA synthesis, lipid metabolism and lipotoxicity
- (2009) Lei O. Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Accumulation of neutral lipids in peripheral blood mononuclear cells as a distinctive trait of Alzheimer patients and asymptomatic subjects at risk of disease
- (2009) Alessandra Pani et al. BMC Medicine
- Clusterin: A forgotten player in Alzheimer's disease
- (2009) Tapio Nuutinen et al. BRAIN RESEARCH REVIEWS
- Overweight in midlife and risk of dementia: a 40-year follow-up study
- (2009) L B Hassing et al. INTERNATIONAL JOURNAL OF OBESITY
- Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1
- (2009) Jacob R. Hascalovici et al. JOURNAL OF NEUROCHEMISTRY
- Increased Association Between Rough Endoplasmic Reticulum Membranes and Mitochondria in Transgenic Mice That Express P301L Tau
- (2009) Sébastien Perreault et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS
- (2009) Haruo Hanyu et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Adeno-associated Virus Gene Therapy With Cholesterol 24-Hydroxylase Reduces the Amyloid Pathology Before or After the Onset of Amyloid Plaques in Mouse Models of Alzheimer's Disease
- (2009) Eloise Hudry et al. MOLECULAR THERAPY
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
- (2009) Tomohiko Sato et al. NEUROBIOLOGY OF AGING
- Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial
- (2009) Samuel T Henderson et al. Nutrition & Metabolism
- Lipid-Induced ER Stress: Synergistic Effects of Sterols and Saturated Fatty Acids
- (2009) Ludovic Pineau et al. TRAFFIC
- Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)
- (2008) ARCHIVES OF NEUROLOGY
- Starving Neurons Show Sex Difference in Autophagy
- (2008) Lina Du et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
- (2008) Rene O Sanchez-Mejia et al. NATURE NEUROSCIENCE
- Deregulation of sphingolipid metabolism in Alzheimer's disease
- (2008) Xingxuan He et al. NEUROBIOLOGY OF AGING
- Ceramide elevates 12-hydroxyeicosatetraenoic acid levels and upregulates 12-lipoxygenase in rat primary hippocampal cell cultures containing predominantly astrocytes
- (2008) Vidudala V.T.S. Prasad et al. NEUROCHEMISTRY INTERNATIONAL
- Central obesity and increased risk of dementia more than three decades later
- (2008) R. A. Whitmer et al. NEUROLOGY
- Protective effects of NSAIDs on the development of Alzheimer disease
- (2008) Steven C. Vlad et al. NEUROLOGY
- Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease
- (2008) Maria-Paz Marzolo et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started