标题
The IL-17-Th1/Th17 pathway: an attractive target for lung cancer therapy?
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 20, Issue 11, Pages 1339-1356
出版商
Informa UK Limited
发表日期
2016-06-29
DOI
10.1080/14728222.2016.1206891
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis
- (2016) Antoine Guillon et al. EUROPEAN RESPIRATORY JOURNAL
- P-148 Discovery of Novel Oral Peptide Antagonists of IL-23 Receptor that Are Efficacious in a Rat Model of IBD
- (2016) Ashok Bhandari et al. INFLAMMATORY BOWEL DISEASES
- O-001 A Multicenter, Double-Blind, Placebo-Controlled Phase3 Study of Ustekinumab, a Human IL-12/23P40 mAB, in Moderate-Service Crohnʼs Disease Refractory to Anti-TFNα
- (2016) William Sandborn et al. INFLAMMATORY BOWEL DISEASES
- Mangiferin corrects the imbalance of Th17/Treg cells in mice with TNBS-induced colitis
- (2016) Su-Min Lim et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Efficacy of a novel phosphodiesterase inhibitor, E6005, in patients with atopic dermatitis: An investigator-blinded, vehicle-controlled study
- (2016) Fuminori Ohba et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Brodalumab and suicidal ideation in the context of a recent economic crisis in the United States
- (2016) Melissa J. Danesh et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Interleukin-22 promotes lung cancer cell proliferation and migration via the IL-22R1/STAT3 and IL-22R1/AKT signaling pathways
- (2016) Yi Bi et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer
- (2015) Bo Pan et al. BIOMARKERS
- Tildrakizumab (MK-3222), an anti-interleukin-23p19 monoclonal antibody, improves psoriasis in a phase IIb randomized placebo-controlled trial
- (2015) K. Papp et al. BRITISH JOURNAL OF DERMATOLOGY
- Association between Th17-related cytokines and risk of non-small cell lung cancer among patients with or without chronic obstructive pulmonary disease
- (2015) Chen Liao et al. CANCER
- Activated STAT3 correlates with prognosis of non-small cell lung cancer and indicates new anticancer strategies
- (2015) Yang Yu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
- (2015) Peijing Zhang et al. CELL CYCLE
- KDM6B Elicits Cell Apoptosis by Promoting Nuclear Translocation of FOXO1 in Non-Small Cell Lung Cancer
- (2015) Jun Ma et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Association of intra-tumoral tumour-infiltrating lymphocytes and neutrophil-to-lymphocyte ratio is an independent prognostic factor in non-small cell lung cancer
- (2015) Nigar Dirican et al. Clinical Respiratory Journal
- An inhaled phosphodiesterase 4 inhibitor E6005 suppresses pulmonary inflammation in mice
- (2015) Shingo Kubota et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Tumour islet Foxp3+T-cell infiltration predicts poor outcome in nonsmall cell lung cancer
- (2015) Dermot S. O'Callaghan et al. EUROPEAN RESPIRATORY JOURNAL
- Disturbed Th17/Treg Balance in Patients with Non-small Cell Lung Cancer
- (2015) Min-Chao Duan et al. INFLAMMATION
- Tildrakizumab, a novel anti-IL-23 monoclonal antibody, is unaffected by ethnic variability in Caucasian, Chinese, and Japanese subjects
- (2015) Anthe Zandvliet et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Anti–IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial
- (2015) James G. Krueger et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Retinoic acid-related orphan receptor C isoform 2 expression and its prognostic significance for non-small cell lung cancer
- (2015) Qi Huang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed
- (2015) Herbert I. Hurwitz et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety, tolerability and pharmacokinetics of a novel phosphodiesterase inhibitor, E6005 ointment, in healthy volunteers and in patients with atopic dermatitis
- (2015) Fuminori Ohba et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Effect of topical phosphodiesterase 4 inhibitor E6005 on Japanese children with atopic dermatitis: Results from a randomized, vehicle-controlled exploratory trial
- (2015) Osamu Nemoto et al. JOURNAL OF DERMATOLOGY
- Baicalin Alleviates Silica-Induced Lung Inflammation and Fibrosis by Inhibiting the Th17 Response in C57BL/6 Mice
- (2015) Tao Liu et al. JOURNAL OF NATURAL PRODUCTS
- Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial
- (2015) Diamant Thaçi et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)
- (2015) Kim Papp et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Objective Measurement and Clinical Significance of TILs in Non–Small Cell Lung Cancer
- (2015) Kurt A. Schalper et al. JNCI-Journal of the National Cancer Institute
- Effect of methotrexate on JAK/STAT pathway activation in myeloproliferative neoplasms
- (2015) Sally Thomas et al. LANCET
- Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials
- (2015) Christopher E M Griffiths et al. LANCET
- Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial
- (2015) Hervé Bachelez et al. LANCET
- Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial
- (2015) Iain B McInnes et al. LANCET
- Clinical improvement in psoriasis with specific targeting of interleukin-23
- (2015) Tamara Kopp et al. NATURE
- Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis
- (2015) Mark Lebwohl et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis
- (2015) Kenneth B. Gordon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis
- (2015) Annemarie E. M. van Nieuwenhuijze et al. ARTHRITIS RESEARCH & THERAPY
- The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation
- (2015) Zhi Liu et al. Journal of Molecular Cell Biology
- BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer
- (2015) Niki Karachaliou et al. Scientific Reports
- Objective Measurement and Clinical Significance of TILs in Non–Small Cell Lung Cancer
- (2015) Kurt A. Schalper et al. JNCI-Journal of the National Cancer Institute
- Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer
- (2015) Bo Pan et al. Scientific Reports
- Promotion of lung tumor growth by interleukin-17
- (2014) Beibei Xu et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial
- (2014) Christopher Ritchlin et al. ANNALS OF THE RHEUMATIC DISEASES
- Ustekinumab, an anti-IL-12/23 p40 monoclonal antibody, inhibits radiographic progression in patients with active psoriatic arthritis: results of an integrated analysis of radiographic data from the phase 3, multicentre, randomised, double-blind, placebo-controlled PSUMMIT-1 and PSUMMIT-2 trials
- (2014) Arthur Kavanaugh et al. ANNALS OF THE RHEUMATIC DISEASES
- Detection and significance of TregFoxP3+ and Th17 cells in peripheral blood of non-small cell lung cancer patients
- (2014) Sha Li et al. Archives of Medical Science
- Serum interleukin-17 as a diagnostic and prognostic marker for non-small cell lung cancer
- (2014) Chunhua Xu et al. BIOMARKERS
- Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects
- (2014) Hongwei Tian et al. BMC CANCER
- Tumor-specific oncolytic adenoviruses expressing granulocyte macrophage colony-stimulating factor or anti-CTLA4 antibody for the treatment of cancers
- (2014) T Du et al. CANCER GENE THERAPY
- Genetic Polymorphisms and Plasma Levels of Interleukin-22 Contribute to the Development of Nonsmall Cell Lung Cancer
- (2014) Fei Liu et al. DNA AND CELL BIOLOGY
- Inhibiting RORγt/Th17 axis for autoimmune disorders
- (2014) Fujio Isono et al. DRUG DISCOVERY TODAY
- Phosphorylated STAT3 and PD-1 regulate IL-17 production and IL-23 receptor expression inMycobacterium tuberculosisinfection
- (2014) Anuradha Bandaru et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Chemopreventive effect of phosphodieasterase-4 inhibition in benzo(a)pyrene-induced murine lung cancer model
- (2014) Chang Dong Yeo et al. EXPERIMENTAL LUNG RESEARCH
- Embelin suppresses pancreatic cancer growth by modulating tumor immune microenvironment
- (2014) Justine Marsh Frontiers in Bioscience-Landmark
- Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: Results of a randomized, vehicle-controlled, multicenter clinical trial
- (2014) Masutaka Furue et al. JOURNAL OF DERMATOLOGY
- Sulforaphane Protects from T Cell-Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells
- (2014) J. Geisel et al. JOURNAL OF IMMUNOLOGY
- The effect of proinflammatory cytokines on IL-17RA expression in NSCLC
- (2014) Qi Huang et al. MEDICAL ONCOLOGY
- IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology
- (2014) L Chen et al. Mucosal Immunology
- Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis
- (2014) Philip J. Mease et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tofacitinib versus Methotrexate in Rheumatoid Arthritis
- (2014) Eun Bong Lee et al. NEW ENGLAND JOURNAL OF MEDICINE
- Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
- (2014) Richard G. Langley et al. NEW ENGLAND JOURNAL OF MEDICINE
- T helper 17 cells play a critical pathogenic role in lung cancer
- (2014) S. H. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells
- (2014) R. Noster et al. Science Translational Medicine
- Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation
- (2014) Qingtian Li et al. Nature Communications
- Phosphodiesterase (PDE)-4 Inhibitors and COPD Correlation with Cancer
- (2014) John Organtzis et al. Journal of Cancer
- A Phase II Randomized Study of Subcutaneous Ixekizumab, an Anti-Interleukin-17 Monoclonal Antibody, in Rheumatoid Arthritis Patients Who Were Naive to Biologic Agents or Had an Inadequate Response to Tumor Necrosis Factor Inhibitors
- (2014) Mark C. Genovese et al. Arthritis & Rheumatology
- Th17 Cells in Cancer: The Ultimate Identity Crisis
- (2014) Stefanie R. Bailey et al. Frontiers in Immunology
- Current status of granulocyte–macrophage colony-stimulating factor in the immunotherapy of melanoma
- (2014) Howard L Kaufman et al. Journal for ImmunoTherapy of Cancer
- Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis
- (2013) Joel Kremer et al. ANNALS OF INTERNAL MEDICINE
- Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
- (2013) Iain B McInnes et al. ANNALS OF THE RHEUMATIC DISEASES
- Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four-month phase III randomized radiographic study
- (2013) Désirée van der Heijde et al. ARTHRITIS AND RHEUMATISM
- The safety profile of ustekinumab in the treatment of patients with psoriasis and concurrent hepatitis B or C
- (2013) H.-Y. Chiu et al. BRITISH JOURNAL OF DERMATOLOGY
- Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up
- (2013) K.A. Papp et al. BRITISH JOURNAL OF DERMATOLOGY
- PIKfyve, a Class III PI Kinase, Is the Target of the Small Molecular IL-12/IL-23 Inhibitor Apilimod and a Player in Toll-like Receptor Signaling
- (2013) Xinming Cai et al. CHEMISTRY & BIOLOGY
- Ciclosporin A inhibits production of interleukin-12/23p40 and interleukin-23 by the human monocyte cell line, THP-1
- (2013) M. Kamata et al. CLINICAL AND EXPERIMENTAL DERMATOLOGY
- Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
- (2013) J. Ferlay et al. EUROPEAN JOURNAL OF CANCER
- From the Medical Board of the National Psoriasis Foundation: Recommendations for screening for hepatitis B infection prior to initiating anti–tumor necrosis factor-alfa inhibitors or other immunosuppressive agents in patients with psoriasis
- (2013) Kiran Motaparthi et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Interleukin-22 Is Frequently Expressed in Small- and Large-Cell Lung Cancer and Promotes Growth in Chemotherapy-Resistant Cancer Cells
- (2013) Sebastian Kobold et al. Journal of Thoracic Oncology
- Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
- (2013) Iain B McInnes et al. LANCET
- Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial
- (2013) Gerd R Burmester et al. LANCET
- Therapeutic opportunities of the IL-22–IL-22R1 system
- (2013) Robert Sabat et al. NATURE REVIEWS DRUG DISCOVERY
- Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
- (2013) Y. Rui et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A balance of interleukin-12 and -23 in cancer
- (2013) Shin Foong Ngiow et al. TRENDS IN IMMUNOLOGY
- The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4+T cells
- (2013) Shamaila Munir et al. OncoImmunology
- IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer
- (2013) Anne-Marie Baird et al. Frontiers in Oncology
- Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator
- (2012) Naresh Kumar et al. ACS Chemical Biology
- Review: Nonradiographic axial spondyloarthritis: New definition of an old disease?
- (2012) Joachim Sieper et al. ARTHRITIS AND RHEUMATISM
- Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomised, double-blind, placebo-controlled, phase II regimen-finding study
- (2012) P. Rich et al. BRITISH JOURNAL OF DERMATOLOGY
- DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer
- (2012) Xavier Tekpli et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Interleukin 22-producing CD4+ T cells in malignant pleural effusion
- (2012) Zhi-Jian Ye et al. CANCER LETTERS
- Functional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populations
- (2012) Jian Zheng et al. CARCINOGENESIS
- Interleukin 23 regulates proliferation of lung cancer cells in a concentration-dependent way in association with the interleukin-23 receptor
- (2012) Jun Li et al. CARCINOGENESIS
- A Validated Regulatory Network for Th17 Cell Specification
- (2012) Maria Ciofani et al. CELL
- U.S. Food and Drug Administration Approval: Ruxolitinib for the Treatment of Patients with Intermediate and High-Risk Myelofibrosis
- (2012) A. Deisseroth et al. CLINICAL CANCER RESEARCH
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
- (2012) Wolfgang Hueber et al. GUT
- Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2
- (2012) Xiaohu Wang et al. IMMUNITY
- Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1
- (2012) Kiyoshi Hirahara et al. IMMUNITY
- Conserved Intergenic Elements and DNA Methylation Cooperate to Regulate Transcription at theil17Locus
- (2012) Rajan M. Thomas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PD-1 Blockade Augments Th1 and Th17 and Suppresses Th2 Responses in Peripheral Blood From Patients With Prostate and Advanced Melanoma Cancer
- (2012) John Dulos et al. JOURNAL OF IMMUNOTHERAPY
- Differential regulation of CD4+ T helper cell responses by curcumin in experimental autoimmune encephalomyelitis
- (2012) Saravanan Kanakasabai et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis
- (2012) Naresh Punwani et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- IL-23 is pro-proliferative, epigenetically regulated and modulated by chemotherapy in non-small cell lung cancer
- (2012) Anne-Marie Baird et al. LUNG CANCER
- Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis
- (2012) Kim A. Papp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis
- (2012) Craig Leonardi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Placebo-Controlled Trial of Tofacitinib Monotherapy in Rheumatoid Arthritis
- (2012) Roy Fleischmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF
- (2012) S S Pullamsetti et al. ONCOGENE
- STAT3 Is Activated by JAK2 Independent of Key Oncogenic Driver Mutations in Non-Small Cell Lung Carcinoma
- (2012) Brendan D. Looyenga et al. PLoS One
- Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis
- (2012) Yumiko Wada et al. PLoS One
- Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ
- (2012) Hiroyuki Kojima et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The split nature of tumor-infiltrating leukocytes
- (2012) Telma Lança et al. OncoImmunology
- Interleukin-23: A key cytokine in inflammatory diseases
- (2011) Emilie Duvallet et al. ANNALS OF MEDICINE
- Brief Report: A phase IIa, randomized, double-blind, placebo-controlled trial of apilimod mesylate, an interleukin-12/interleukin-23 inhibitor, in patients with rheumatoid arthritis
- (2011) Sarah Krausz et al. ARTHRITIS AND RHEUMATISM
- Effects of IL-17A on the occurrence of lung adenocarcinoma
- (2011) Ying Li et al. CANCER BIOLOGY & THERAPY
- IL-20 is epigenetically regulated in NSCLC and down regulates the expression of VEGF
- (2011) Anne-Marie Baird et al. EUROPEAN JOURNAL OF CANCER
- Interleukin-17-educated monocytes suppress cytotoxic T-cell function through B7-H1 in hepatocellular carcinoma patients
- (2011) Qiyi Zhao et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- IL-23/IL-23R: potential mediator of intestinal tumor progression from adenomatous polyps to colorectal carcinoma
- (2011) Feng Lan et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein
- (2011) Tao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Efficacy and safety of ustekinumab for the treatment of moderate-to-severe psoriasis: A phase III, randomized, placebo-controlled trial in Taiwanese and Korean patients (PEARL)
- (2011) Tsen-Fang Tsai et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- The Link between the PDL1 Costimulatory Pathway and Th17 in Fetomaternal Tolerance
- (2011) F. D'Addio et al. JOURNAL OF IMMUNOLOGY
- A Phase III, Randomized, Controlled Trial of the Fully Human IL-12/23 mAb Briakinumab in Moderate-to-Severe Psoriasis
- (2011) Kenneth B. Gordon et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- GM-CSF: the secret weapon in the TH17 arsenal
- (2011) Mandy J McGeachy NATURE IMMUNOLOGY
- A 52-Week Trial Comparing Briakinumab with Methotrexate in Patients with Psoriasis
- (2011) Kristian Reich et al. NEW ENGLAND JOURNAL OF MEDICINE
- A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer
- (2011) S. Reppert et al. Nature Communications
- The Role of Epigenetics in Resistance to Cisplatin Chemotherapy in Lung Cancer
- (2011) Kenneth J. O’Byrne et al. Cancers
- Differentiation of Effector CD4 T Cell Populations
- (2010) Jinfang Zhu et al. Annual Review of Immunology
- Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease
- (2010) Reiko M. Onishi et al. IMMUNOLOGY
- Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis
- (2010) G. Tonel et al. JOURNAL OF IMMUNOLOGY
- The Role of Inflammation in the Pathogenesis of Non-small Cell Lung Cancer
- (2010) Dermot S. O'Callaghan et al. Journal of Thoracic Oncology
- Comparison of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis
- (2010) Christopher E.M. Griffiths et al. NEW ENGLAND JOURNAL OF MEDICINE
- Th17 cells in ovarian cancer
- (2009) D. H. Munn BLOOD
- Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
- (2009) I. Kryczek et al. BLOOD
- Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohnʼs disease
- (2009) Bruce E. Sands et al. INFLAMMATORY BOWEL DISEASES
- Oxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy
- (2009) Matthew W. Lawless et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans
- (2009) Kellie A. Charles et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway
- (2009) Lin Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression and Activity of Phosphodiesterase Isoforms during Epithelial Mesenchymal Transition: The Role of Phosphodiesterase 4
- (2009) Ewa Kolosionek et al. MOLECULAR BIOLOGY OF THE CELL
- Properties and origin of human Th17 cells
- (2009) Sergio Romagnani et al. MOLECULAR IMMUNOLOGY
- Antiapoptotic Activity of Autocrine Interleukin-22 and Therapeutic Effects of Interleukin-22-Small Interfering RNA on Human Lung Cancer Xenografts
- (2008) W. Zhang et al. CLINICAL CANCER RESEARCH
- Targeting histone deacetylases for the treatment of disease
- (2008) M. W. Lawless et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
- (2008) Craig L Leonardi et al. LANCET
- Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
- (2008) Kim A Papp et al. LANCET
- A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
- (2008) Elisabetta Volpe et al. NATURE IMMUNOLOGY
- High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas
- (2007) S Le Gouvello et al. GUT
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started