Nutraceutical Strategies for Suppressing NLRP3 Inflammasome Activation: Pertinence to the Management of COVID-19 and Beyond
出版年份 2020 全文链接
标题
Nutraceutical Strategies for Suppressing NLRP3 Inflammasome Activation: Pertinence to the Management of COVID-19 and Beyond
作者
关键词
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出版物
Nutrients
Volume 13, Issue 1, Pages 47
出版商
MDPI AG
发表日期
2020-12-25
DOI
10.3390/nu13010047
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance
- (2020) Ming He et al. Cell Metabolism
- Inflammasomes contributing to inflammation in arthritis
- (2020) Lotte Spel et al. IMMUNOLOGICAL REVIEWS
- Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration
- (2020) Yun Gao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of NLRP3 Inflammasome in Infection-related, Immune-mediated and Autoimmune Skin Diseases
- (2020) Dan Wang et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Melatonin protects the retina from experimental non‐exudative age‐relatd macular degeneration in mice
- (2020) Hernán H. Diéguez et al. JOURNAL OF PINEAL RESEARCH
- Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus
- (2020) Mark F. McCarty et al. PROGRESS IN CARDIOVASCULAR DISEASES
- Reactive oxygen species play a role in P2X7 receptor-mediated IL-6 production in spinal astrocytes
- (2020) Frances M. Munoz et al. Purinergic Signalling
- Spirulina maxima extract prevents activation of the NLRP3 inflammasome by inhibiting ERK signaling
- (2020) Sungwoo Chei et al. Scientific Reports
- Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis
- (2020) Weijian Mai et al. Frontiers in Pharmacology
- The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions
- (2020) Rameez Hassan Pirzada et al. Genes
- Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis
- (2020) Pan Luo et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- C‐phycocyanin protects against ethanol‐induced gastric ulcers in rats: Role of HMGB1/NLRP3/NF‐κB pathway
- (2020) Amany Abdel‐mageed Alzokaky et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Sulforaphane ameliorates serum starvation‐induced muscle atrophy via activation of the Nrf2 pathway in cultured C2C12 cells
- (2020) Jae Yun Moon et al. CELL BIOLOGY INTERNATIONAL
- Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
- (2020) Antonio Abbate et al. CIRCULATION RESEARCH
- Hydrogen sulfide alleviates liver injury via S-sulfhydrated-Keap1/Nrf2/LRP1 pathway
- (2020) Shuang Zhao et al. HEPATOLOGY
- Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice
- (2020) Jiaji Lei et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)
- (2020) Anatoly Skalny et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- COVID-19 and the role of chronic inflammation in patients with obesity
- (2020) Sonja Chiappetta et al. INTERNATIONAL JOURNAL OF OBESITY
- Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS
- (2020) Hui Liu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Association of zinc administration with growth suppression of intracranial aneurysms via induction of A20
- (2020) Kosuke Hayashi et al. JOURNAL OF NEUROSURGERY
- N-Acetylcysteine: a potential therapeutic agent for SARS-CoV-2
- (2020) Francis L. Poe et al. MEDICAL HYPOTHESES
- Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Coronavirusxs
- (2020) Georgios Renieris et al. SHOCK
- Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19
- (2020) Adnan Shah Frontiers in Immunology
- SIRT1 Alleviates LPS-Induced IL-1β Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts
- (2020) Sumi Park et al. Cells
- Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction
- (2020) Angélique Chevriaux et al. Frontiers in Cell and Developmental Biology
- Association between treatment with colchicine and improved survival in a single-centre cohort of adult hospitalised patients with COVID-19 pneumonia and acute respiratory distress syndrome
- (2020) Mirko Scarsi et al. ANNALS OF THE RHEUMATIC DISEASES
- Antiviral activity of berberine
- (2020) Alicja Warowicka et al. ARCHIVES OF VIROLOGY
- The Minimal Effect of Zinc on the Survival of Hospitalized Patients With COVID-19
- (2020) Jasper Seth Yao et al. CHEST
- Aging, Male Sex, Obesity, and Metabolic Inflammation Create the Perfect Storm for COVID-19
- (2020) Franck Mauvais-Jarvis DIABETES
- N-acetylcysteine as a potential treatment for novel coronavirus disease 2019
- (2020) Rangel-Méndez Jorge-Aarón et al. Future Microbiology
- Successful Treatment of Covid-19 Associated Cytokine Release Syndrome with Colchicine. A Case Report and Review of Literature
- (2020) Nahal Mansouri et al. IMMUNOLOGICAL INVESTIGATIONS
- Melatonin prevents endothelial dysfunction in SLE by activating the nuclear receptor retinoic acid-related orphan receptor-α
- (2020) Huijing Huang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Physiological concentrations of bilirubin control inflammatory response by inhibiting NF-κB and inflammasome activation
- (2020) Yufei Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Treatment of SARS-CoV-2 with high dose oral zinc salts: A report on four patients
- (2020) Eric Finzi INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Nutraceutical Compounds Targeting Inflammasomes in Human Diseases
- (2020) Beatriz Castejón-Vega et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Increasing complexity of NLRP3 inflammasome regulation
- (2020) Julien Moretti et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Visceral Adiposity and High Intramuscular Fat Deposition Independently Predict Critical Illness in Patients with Sars‐COV‐2
- (2020) Yang Yang et al. Obesity
- Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19
- (2020) Raphaël Cauchois et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis
- (2020) Jean-Christophe Lagier et al. Travel Medicine and Infectious Disease
- KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease
- (2020) Sharadha Dayalan Naidu et al. Open Biology
- Use of Anakinra to Prevent Mechanical Ventilation in Severe COVID‐19: A Case Series
- (2020) Iris Navarro‐Millán et al. Arthritis & Rheumatology
- Severe COVID-19: NLRP3 Inflammasome Dysregulated
- (2020) Daan F. van den Berg et al. Frontiers in Immunology
- Targeting the NLRP3 Inflammasome in Severe COVID-19
- (2020) Tracey L. Freeman et al. Frontiers in Immunology
- SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion
- (2020) Ying Han et al. Redox Biology
- Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6
- (2020) Bhavana Chhunchha et al. Cells
- The Integrative Role of Sulforaphane in Preventing Inflammation, Oxidative Stress and Fatigue: A Review of a Potential Protective Phytochemical
- (2020) Ruheea Taskin Ruhee et al. Antioxidants
- Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections
- (2020) Frank A. D. T. G. Wagener et al. Antioxidants
- Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019
- (2020) Spyridon G. Deftereos et al. JAMA Network Open
- The development of a targeted and more potent, anti-Inflammatory derivative of colchicine: Implications for gout
- (2020) Guillaume Paré et al. BIOCHEMICAL PHARMACOLOGY
- Identification of potential inhibitors against SARS-CoV-2 by targeting proteins responsible for envelope formation and virion assembly using docking based virtual screening, and pharmacokinetics approaches
- (2020) Deep Bhowmik et al. INFECTION GENETICS AND EVOLUTION
- The role of visceral adiposity in the severity of COVID-19: Highlights from a unicenter cross-sectional pilot study in Germany
- (2020) Antonia Petersen et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The Protective Effects of Melatonin on Aluminum-Induced Hepatotoxicity and Nephrotoxicity in Rats
- (2020) Mohamed S. Othman et al. Oxidative Medicine and Cellular Longevity
- Plasma Membrane Pores Drive Inflammatory Cell Death
- (2020) Benedikt Kolbrink et al. Frontiers in Cell and Developmental Biology
- Recent insights into the regulatory networks of NLRP3 inflammasome activation
- (2020) Alexander N. R. Weber et al. JOURNAL OF CELL SCIENCE
- Inhibiting the NLRP3 Inflammasome
- (2020) Lina Y. El-Sharkawy et al. MOLECULES
- Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
- (2019) Li-Shuang Zhang et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina
- (2019) Alireza Badiei et al. EXPERIMENTAL EYE RESEARCH
- Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells
- (2019) Li Hongxia et al. JOURNAL OF AFFECTIVE DISORDERS
- Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome
- (2019) Ming Qin et al. FREE RADICAL BIOLOGY AND MEDICINE
- The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms
- (2019) Jan Korbecki et al. INFLAMMATION RESEARCH
- Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome
- (2019) Hsiao-Wen Chiu et al. Scientific Reports
- Recent Strategies in Resveratrol Delivery Systems
- (2019) Noelia D. Machado et al. ChemPlusChem
- Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell
- (2019) Mingjiang Yao et al. BMC Complementary and Alternative Medicine
- MAVS O-GlcNAcylation Is Essential for Host Antiviral Immunity against Lethal RNA Viruses
- (2019) Nan Song et al. Cell Reports
- The effects of phycocyanin on bleomycin-induced pulmonary fibrosis and the intestinal microbiota in C57BL/6 mice
- (2019) Yuanyuan Xie et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Control of the inflammasome by the ubiquitin system
- (2019) Gloria Lopez‐Castejon FEBS Journal
- Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-κB signaling in acute pancreatitis
- (2019) Hong-zhong Jin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A diet rich in taurine, cysteine, folate, B12 and betaine may lessen risk for Alzheimer’s disease by boosting brain synthesis of hydrogen sulfide
- (2019) Mark F. McCarty et al. MEDICAL HYPOTHESES
- NLRP3 inflammasome activation drives tau pathology
- (2019) Christina Ising et al. NATURE
- Emerging Activators and Regulators of Inflammasomes and Pyroptosis
- (2019) Yansong Xue et al. TRENDS IN IMMUNOLOGY
- Dietary Curcumin: Correlation between Bioavailability and Health Potential
- (2019) Michele Dei Cas et al. Nutrients
- Association between Metformin and a Lower Risk of Age-Related Macular Degeneration in Patients with Type 2 Diabetes
- (2019) Yu-Yen Chen et al. Journal of Ophthalmology
- Melatonin Target Proteins: Too Many or Not Enough?
- (2019) Lei Liu et al. Frontiers in Endocrinology
- Targeting NLRP3 Inflammasome Activation in Severe Asthma
- (2019) Efthymia Theofani et al. Journal of Clinical Medicine
- Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats
- (2019) Ayman M. Mahmoud et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- A new research hot spot: The role of NLRP3 inflammasome activation, a key step in pyroptosis, in diabetes and diabetic complications
- (2019) Zi-Wei Yu et al. LIFE SCIENCES
- Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights
- (2018) Tadayoshi Karasawa et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- O-Linked β-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-κB (Nuclear Factor-κB) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial InjuryHighlights
- (2018) Dan Yao et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats
- (2018) Ahmed M. Fayez et al. BIOMEDICINE & PHARMACOTHERAPY
- Apocynin inhibited NLRP3/XIAP signalling to alleviate renal fibrotic injury in rat diabetic nephropathy
- (2018) Rui Xin et al. BIOMEDICINE & PHARMACOTHERAPY
- MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration
- (2018) Eunju Lee et al. CELL DEATH AND DIFFERENTIATION
- Assessments of cellular melatonin receptor signaling pathways: β-arrestin recruitment, receptor internalization, and impedance variations
- (2018) Clémence Dupré et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- ATP/P2X7-NLRP3 axis of dendritic cells participates in the regulation of airway inflammation and hyper-responsiveness in asthma by mediating HMGB1 expression and secretion
- (2018) Ruiting Li et al. EXPERIMENTAL CELL RESEARCH
- Ferulic acid protects against heat stress-induced intestinal epithelial barrier dysfunction in IEC-6 cells via the PI3K/Akt-mediated Nrf2/HO-1 signaling pathway
- (2018) Shasha He et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease
- (2018) Michal Hershfinkel INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients
- (2018) Lisa G. Wood et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome
- (2018) Haipeng Yin et al. JOURNAL OF IMMUNOLOGY
- Inhibition of the hepatic Nlrp3 protects dopaminergic neurons via attenuating systemic inflammation in a MPTP/p mouse model of Parkinson’s disease
- (2018) Chen Qiao et al. Journal of Neuroinflammation
- Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB
- (2018) Jakob Voelkl et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Ferulic acid may target MyD88-mediated pro-inflammatory signaling – Implications for the health protection afforded by whole grains, anthocyanins, and coffee
- (2018) Mark F. McCarty et al. MEDICAL HYPOTHESES
- Circadian modification network of a core clock driver BMAL1 to harmonize physiology from brain to peripheral tissues
- (2018) Teruya Tamaru et al. NEUROCHEMISTRY INTERNATIONAL
- A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation
- (2018) Sofie Voet et al. Nature Communications
- Ferulic Acid Supplementation Improves Lipid Profiles, Oxidative Stress, and Inflammatory Status in Hyperlipidemic Subjects: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
- (2018) Akkarach Bumrungpert et al. Nutrients
- Evaluation on the effect of hydrogen sulfide on the NLRP3 signaling pathway and its involvement in the pathogenesis of atherosclerosis
- (2018) Li-Ming Yue et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Ferulic Acid Rescues LPS-Induced Neurotoxicity via Modulation of the TLR4 Receptor in the Mouse Hippocampus
- (2018) Shafiq Ur Rehman et al. MOLECULAR NEUROBIOLOGY
- Efficacy and safety of berberine for dyslipidaemias: a systematic review and meta-analysis of randomized clinical trials
- (2018) Jianqing Ju et al. PHYTOMEDICINE
- Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2
- (2018) James O. Early et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NLRP3 inflammasome activation in inflammaging
- (2018) Eicke Latz et al. SEMINARS IN IMMUNOLOGY
- Selenium Attenuates Staphylococcus aureus Mastitis in Mice by Inhibiting the Activation of the NALP3 Inflammasome and NF-κB/MAPK Pathway
- (2018) Junkun Ma et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Glucosamine improves survival in a mouse model of sepsis and attenuates sepsis-induced lung injury and inflammation
- (2018) Ji-Sun Hwang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- β-arrestin2 regulates the anti-inflammatory effects of Salmeterol in lipopolysaccharide-stimulated BV2 cells
- (2018) Monika Sharma et al. JOURNAL OF NEUROIMMUNOLOGY
- Periodontal ligament fibroblasts migration injury via ROS/TXNIP/Nlrp3 inflammasome pathway with Porphyromonas gingivalis lipopolysaccharide
- (2018) Dawei Lian et al. MOLECULAR IMMUNOLOGY
- Upregulation of proteins of the NLRP3 inflammasome in patients with periodontitis and uncontrolled type 2 diabetes
- (2018) Ana Lilia García‐Hernández et al. ORAL DISEASES
- Berberine ameliorates lipopolysaccharide-induced acute lung injury via the PERK-mediated Nrf2/HO-1 signaling axis
- (2018) Yuan Liang et al. PHYTOTHERAPY RESEARCH
- The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease
- (2018) Shuo Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Nitric oxide protected against NADPH oxidase-derived superoxide generation in vascular endothelium: Critical role for heme oxygenase-1
- (2018) Mengjuan Luo et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Negative regulation of NLRP3 inflammasome by SIRT1 in vascular endothelial cells
- (2017) Yanxiang Li et al. IMMUNOBIOLOGY
- Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress
- (2017) Ya-Min Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo
- (2017) Zhongkun Ren et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production bothin vitroand in a mouse model of inflammation
- (2017) Mariela Castelblanco et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endogenous hydrogen sulphide attenuates NLRP3 inflammasome-mediated neuroinflammation by suppressing the P2X7 receptor after intracerebral haemorrhage in rats
- (2017) Hengli Zhao et al. Journal of Neuroinflammation
- Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome
- (2017) Zhengwang Cao et al. JOURNAL OF PINEAL RESEARCH
- Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1
- (2017) Peng Zou et al. Molecular Medicine Reports
- cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
- (2017) Nagaraj Kerur et al. NATURE MEDICINE
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury
- (2017) Merry W. Ma et al. Oxidative Medicine and Cellular Longevity
- Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats
- (2017) Yingying Hu et al. Oncotarget
- Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
- (2017) Miaomiao Lu et al. Biomed Research International
- The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways
- (2017) Xubo Chen et al. Redox Biology
- Hydrogen Sulphide Treatment Increases Insulin Sensitivity and Improves Oxidant Metabolism through the CaMKKbeta-AMPK Pathway in PA-Induced IR C2C12 Cells
- (2017) Xubo Chen et al. Scientific Reports
- Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled trial
- (2016) Junaidah B Barnett et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx
- (2016) Michael A. Katsnelson et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- RORα is not a receptor for melatonin (response to DOI 10.1002/bies.201600018)
- (2016) Andrzej T. Slominski et al. BIOESSAYS
- NLRP3 inflammasome as a target of berberine in experimental murine liver injury: interference with P2X7 signalling
- (2016) E. Vivoli et al. CLINICAL SCIENCE
- Hydrogen Sulfide Induces Keap1 S-sulfhydration and Suppresses Diabetes-Accelerated Atherosclerosis via Nrf2 Activation
- (2016) Liping Xie et al. DIABETES
- Medical Application ofSpirulina platensisDerived C-Phycocyanin
- (2016) Qian Liu et al. Evidence-based Complementary and Alternative Medicine
- Angiotensin(1–7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H 2 O 2 -activated NLRP3 inflammasome/IL-1β/Smad circuit
- (2016) Li-Li Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension
- (2016) Qianqian Sun et al. HYPERTENSION
- Inhibitory effects of omega-3 fatty acids on early brain injury after subarachnoid hemorrhage in rats: Possible involvement of G protein-coupled receptor 120/β-arrestin2/TGF-β activated kinase-1 binding protein-1 signaling pathway
- (2016) Jia Yin et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase- and mitochondria-dependent ROS production
- (2016) Ke Wang et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling
- (2016) Yushu Dong et al. JOURNAL OF PINEAL RESEARCH
- Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome
- (2016) Yong Zhang et al. JOURNAL OF PINEAL RESEARCH
- Palmitic acid induces interleukin-1β secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells
- (2016) Koumei Shirasuna et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Targeting inflammatory mediators with ferulic acid, a dietary polyphenol, for the suppression of monosodium urate crystal-induced inflammation in rats
- (2016) Hari Madhuri Doss et al. LIFE SCIENCES
- Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1βAxis in Microglia
- (2016) Da-ming Sui et al. MEDIATORS OF INFLAMMATION
- Colchicine to decrease NLRP3-activated inflammation and improve obesity-related metabolic dysregulation
- (2016) Andrew P. Demidowich et al. MEDICAL HYPOTHESES
- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration
- (2016) Janusz Blasiak et al. Oxidative Medicine and Cellular Longevity
- Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
- (2016) Mausita Karmakar et al. Nature Communications
- Cytoprotective mechanism of ferulic acid against high glucose-induced oxidative stress in cardiomyocytes and hepatocytes
- (2016) Yuan Song et al. Food & Nutrition Research
- Curcumin Represses NLRP3 Inflammasome Activation via TLR4/MyD88/NF-κB and P2X7R Signaling in PMA-Induced Macrophages
- (2016) Fanqi Kong et al. Frontiers in Pharmacology
- Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice
- (2015) José A. García et al. FASEB JOURNAL
- Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics
- (2015) Ang Li et al. Future Medicinal Chemistry
- A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity
- (2015) Bao H. Duong et al. IMMUNITY
- Resveratrol inhibits the acetylated α-tubulin-mediated assembly of the NLRP3-inflammasome
- (2015) Takuma Misawa et al. INTERNATIONAL IMMUNOLOGY
- Complement Component C5a Primes Retinal Pigment Epithelial Cells for Inflammasome Activation by Lipofuscin-mediated Photooxidative Damage
- (2015) Carolina Brandstetter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy
- (2015) Ya-Ping Chang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- K+Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+Signaling
- (2015) Michael A. Katsnelson et al. JOURNAL OF IMMUNOLOGY
- The pathogenic role of the inflammasome in neurodegenerative diseases
- (2015) Leslie C. Freeman et al. JOURNAL OF NEUROCHEMISTRY
- P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite
- (2015) Liang Feng et al. Journal of Neuroinflammation
- Maternal high-zinc diet attenuates intestinal inflammation by reducing DNA methylation and elevating H3K9 acetylation in the A20 promoter of offspring chicks
- (2015) Changwu Li et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable
- (2015) Lucien C. Manchester et al. JOURNAL OF PINEAL RESEARCH
- The Keap1-Nrf2-antioxidant response element pathway: A review of its regulation by melatonin and the proteasome
- (2015) Jerry Vriend et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
- (2015) Zizhen Gong et al. MOLECULAR NUTRITION & FOOD RESEARCH
- NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes
- (2015) Bingbing Sun et al. Small
- Cofactor-independent antiphospholipid antibodies activate the NLRP3-inflammasome via endosomal NADPH-oxidase: implications for the antiphospholipid syndrome
- (2015) Nadine Müller-Calleja et al. THROMBOSIS AND HAEMOSTASIS
- Homocysteine and the risk of age-related macular degeneration: a systematic review and meta-analysis
- (2015) Peirong Huang et al. Scientific Reports
- NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia
- (2015) Pan Gao et al. Journal of Diabetes Research
- CaMKKβ-Dependent Activation of AMP-Activated Protein Kinase Is Critical to Suppressive Effects of Hydrogen Sulfide on Neuroinflammation
- (2014) Xiaomei Zhou et al. ANTIOXIDANTS & REDOX SIGNALING
- CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1
- (2014) Ben Zhou et al. HEPATOLOGY
- A Key Role for Redox Signaling in Rapid P2X7 Receptor-Induced IL-1 Processing in Human Monocytes
- (2014) J. Hewinson et al. JOURNAL OF IMMUNOLOGY
- New Insights into Acne Pathogenesis: Propionibacterium Acnes Activates the Inflammasome
- (2014) Emmanuel Contassot et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Zinc: An antioxidant and anti-inflammatory agent: Role of zinc in degenerative disorders of aging
- (2014) Ananda S. Prasad JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation
- (2014) Soo Jin Yang et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
- (2014) Lieselotte Vande Walle et al. NATURE
- Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase byS-adenosylmethionine
- (2014) June Ereño-Orbea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DICER1/AluRNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration
- (2014) Younghee Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NLRP3 inflammasome activation by mitochondrial ROS in bronchial epithelial cells is required for allergic inflammation
- (2014) S R Kim et al. Cell Death & Disease
- The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
- (2014) Jungwon Hwang et al. Nature Communications
- Cytoprotective Effect of Alpha-Lipoic Acid on Paraquat-Exposed Human Bronchial Epithelial Cells via Activation of Nuclear Factor Erythroid Related Factor-2 Pathway
- (2013) Yong-Sik Kim et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline
- (2013) Yoshiki Koriyama et al. BRAIN RESEARCH
- β-arrestin protects neurons by mediating endogenous opioid arrest of inflammatory microglia
- (2013) X Feng et al. CELL DEATH AND DIFFERENTIATION
- Therapeutic Effect of C-Phycocyanin Extracted from Blue Green Algae in a Rat Model of Acute Lung Injury Induced by Lipopolysaccharide
- (2013) Pak-on Leung et al. Evidence-based Complementary and Alternative Medicine
- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
- (2013) Takuma Misawa et al. NATURE IMMUNOLOGY
- Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress
- (2012) Jing Zheng et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Curcumin uptake and metabolism
- (2012) Manfred Metzler et al. BIOFACTORS
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- (2012) Valeria Tarallo et al. CELL
- Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome
- (2012) Christine M. Oslowski et al. Cell Metabolism
- Genetic support for the role of the NLRP3 inflammasome in psoriasis susceptibility
- (2012) Maria Carlström et al. EXPERIMENTAL DERMATOLOGY
- Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells—Implications for age-related macular degeneration (AMD)
- (2012) Anu Kauppinen et al. IMMUNOLOGY LETTERS
- Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells
- (2012) Mi-Zhen Xia et al. JOURNAL OF PINEAL RESEARCH
- Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling
- (2012) Dingbo Shi et al. JOURNAL OF PINEAL RESEARCH
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Hydrogen Sulfide Lowers Proliferation and Induces Protective Autophagy in Colon Epithelial Cells
- (2012) Ya C. Wu et al. PLoS One
- Bioavailability of resveratrol
- (2011) Thomas Walle Annals of the New York Academy of Sciences
- The inflammasome: an integrated view
- (2011) Olaf Gross et al. IMMUNOLOGICAL REVIEWS
- Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells
- (2011) Hak Joo Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Smoking, Dietary Betaine, Methionine, and Vitamin D in Monozygotic Twins with Discordant Macular Degeneration: Epigenetic Implications
- (2011) Johanna M. Seddon et al. OPHTHALMOLOGY
- GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
- (2010) Da Young Oh et al. CELL
- Glucosamine regulation of LPS-mediated inflammation in human bronchial epithelial cells
- (2010) Yuh-Lin Wu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes
- (2010) N. Shembade et al. SCIENCE
- Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture
- (2010) Aartjan J. W. te Velthuis et al. PLoS Pathogens
- Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells
- (2009) Shyamali Basuroy et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
- (2009) R Terkeltaub et al. ANNALS OF THE RHEUMATIC DISEASES
- Folic Acid, Pyridoxine, and Cyanocobalamin Combination Treatment and Age-Related Macular Degeneration in Women
- (2009) William G. Christen et al. ARCHIVES OF INTERNAL MEDICINE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- Endosomal Nox2 Facilitates Redox-Dependent Induction of NF-κB by TNF-α
- (2008) Qiang Li et al. ANTIOXIDANTS & REDOX SIGNALING
- SIRT1 longevity factor suppresses NF-κB -driven immune responses: regulation of aging via NF-κB acetylation?
- (2008) Antero Salminen et al. BIOESSAYS
- Unknown
- (2008) Ananda Prasad MOLECULAR MEDICINE
- Direct and indirect antioxidant properties of inducers of cytoprotective proteins
- (2008) Albena T. Dinkova-Kostova et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20
- (2007) Su-Chang Lin et al. JOURNAL OF MOLECULAR BIOLOGY
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