标题
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
作者
关键词
-
出版物
NATURE MEDICINE
Volume 24, Issue 1, Pages 50-61
出版商
Springer Nature
发表日期
2017-11-28
DOI
10.1038/nm.4450
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina
- (2016) Xu Wang et al. JOURNAL OF NEUROSCIENCE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
- (2016) Valerian E Kagan et al. Nature Chemical Biology
- Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques
- (2016) Massimo Bonora et al. Nature Protocols
- GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
- (2016) Robin A. Aglietti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
- (2016) Ivan Zanoni et al. SCIENCE
- Programmed necrosis in inflammation: Toward identification of the effector molecules
- (2016) D. Wallach et al. SCIENCE
- Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock
- (2015) Dahai Yang et al. IMMUNITY
- A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines
- (2015) John J. Suschak et al. JOURNAL OF IMMUNOLOGY
- Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage
- (2015) Carolina Brandstetter et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration
- (2015) M. R. Terluk et al. JOURNAL OF NEUROSCIENCE
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression
- (2015) T. Hung et al. SCIENCE
- Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome
- (2015) Bradley D. Gelfand et al. Cell Reports
- Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB Pathway
- (2015) John Karijolich et al. PLoS Pathogens
- Mitochondrial DNA in the regulation of innate immune responses
- (2015) Chunju Fang et al. Protein & Cell
- A Critical Role for Human Caspase-4 in Endotoxin Sensitivity
- (2014) Y. Kajiwara et al. JOURNAL OF IMMUNOLOGY
- IL-18 is not therapeutic for neovascular age-related macular degeneration
- (2014) Yoshio Hirano et al. NATURE MEDICINE
- DICER1/AluRNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration
- (2014) Younghee Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity
- (2014) B. J. Fowler et al. SCIENCE
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
- (2013) John W. Schoggins et al. NATURE
- A2E Induces IL-1ß Production in Retinal Pigment Epithelial Cells via the NLRP3 Inflammasome
- (2013) Owen A. Anderson et al. PLoS One
- Dicer Expression Exhibits a Tissue-Specific Diurnal Pattern That Is Lost during Aging and in Diabetes
- (2013) Yuanqing Yan et al. PLoS One
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- NLRP3 Inflammasome Blockade Inhibits VEGF-A-Induced Age-Related Macular Degeneration
- (2013) Alexander G. Marneros Cell Reports
- Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock
- (2012) Xingmin Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria
- (2012) Vijay A.K. Rathinam et al. CELL
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- (2012) Valeria Tarallo et al. CELL
- Mitochondria: In Sickness and in Health
- (2012) Jodi Nunnari et al. CELL
- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
- (2012) Kenichi Shimada et al. IMMUNITY
- Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells—Implications for age-related macular degeneration (AMD)
- (2012) Anu Kauppinen et al. IMMUNOLOGY LETTERS
- NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
- (2012) Sarah L Doyle et al. NATURE MEDICINE
- Mechanisms of Age-Related Macular Degeneration
- (2012) Jayakrishna Ambati et al. NEURON
- ERK1/2 activation is a therapeutic target in age-related macular degeneration
- (2012) S. Dridi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids
- (2012) P. X. Shaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
- (2011) L. Jin et al. JOURNAL OF IMMUNOLOGY
- Short-interfering RNAs Induce Retinal Degeneration via TLR3 and IRF3
- (2011) Mark E Kleinman et al. MOLECULAR THERAPY
- DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
- (2011) Hiroki Kaneko et al. NATURE
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- MITOCHONDRIAL DNA IS RELEASED BY SHOCK AND ACTIVATES NEUTROPHILS VIA P38 MAP KINASE
- (2010) Qin Zhang et al. SHOCK
- Regional specular microscopy of endothelial cell loss after intracapsular cataract extraction: A preliminary report
- (2009) Masamaru Inaba et al. ACTA OPHTHALMOLOGICA
- Mitochondrial membrane permeabilization in neuronal injury
- (2009) Lorenzo Galluzzi et al. NATURE REVIEWS NEUROSCIENCE
- Active Alu retrotransposons in the human genome
- (2008) E. A. Bennett et al. GENOME RESEARCH
- Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
- (2008) Mark E. Kleinman et al. NATURE
- Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
- (2008) S. L. Fink et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started