Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP

K+Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+Signaling

(2015) Michael A. Katsnelson et al.   JOURNAL OF IMMUNOLOGY

Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+Efflux

(2015) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

Localization and Functionality of the Inflammasome in Neutrophils

(2014) Martina Bakele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

(2014) Neil Romberg et al.   NATURE GENETICS

Extracellular ATP drives systemic inflammation, tissue damage and mortality

(2014) A Cauwels et al.   Cell Death & Disease

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

(2014) Kaiwen W. Chen et al.   Cell Reports

Extracellular ATP mediates the late phase of neutrophil recruitment to the lung in murine models of acute lung injury

(2013) Dilip Shah et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NADPH oxidase derived reactive oxygen species are involved in human neutrophil IL-1β secretion but not in inflammasome activation

(2013) María Laura Gabelloni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1

(2012) X. J. Xu et al.   JOURNAL OF CELL SCIENCE

Fungal antioxidant pathways promote survival against neutrophils during infection

(2012) Sixto M. Leal et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1

(2012) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockouts

(2011) Marianela Masin et al.   BRITISH JOURNAL OF PHARMACOLOGY

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils

(2011) Arun K. Mankan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

The human P2X7 receptor and its role in innate immunity

(2011) J. S. Wiley et al.   TISSUE ANTIGENS

Extracellular ATP Is a Danger Signal Activating P2X7Receptor in Lung Inflammation and Fibrosis

(2010) Nicolas Riteau et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Metaanalysis of P2X7  gene polymorphisms and tuberculosis susceptibility

(2010) Jing Xiao et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Evidence for associations between the purinergic receptor P2X7 (P2RX7) and toxoplasmosis

(2010) S E Jamieson et al.   GENES AND IMMUNITY

Human neutrophils do not express purinergic P2X7 receptors

(2010) Guadalupe Martel-Gallegos et al.   Purinergic Signalling

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Caspase 1–independent activation of interleukin-1β in neutrophil-predominant inflammation

(2009) Monica Guma et al.   ARTHRITIS AND RHEUMATISM

Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors

(2009) Diana L Donnelly-Roberts et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Functional P2X7 Splice Variant with an Alternative Transmembrane Domain 1 Escapes Gene Inactivation in P2X7 Knock-out Mice

(2009) Annette Nicke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lymphocytes from P2X7 -deficient mice exhibit enhanced P2X7 responses

(2009) Simon R. J. Taylor et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The P2X7 receptor and intracellular pathogens: a continuing struggle

(2009) Robson Coutinho-Silva et al.   Purinergic Signalling

Extracellular ATP in the Immune System: More Than Just a "Danger Signal"

(2009) A. Trautmann   Science Signaling

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology