标题
Regulation and repurposing of nutrient sensing and autophagy in innate immunity
作者
关键词
-
出版物
Autophagy
Volume -, Issue -, Pages 1-21
出版商
Informa UK Limited
发表日期
2020-07-06
DOI
10.1080/15548627.2020.1783119
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- Intersections between Regulated Cell Death and Autophagy
- (2019) Francesco Napoletano et al. TRENDS IN CELL BIOLOGY
- The Human Cytomegalovirus UL38 protein drives mTOR-independent metabolic flux reprogramming by inhibiting TSC2
- (2019) Irene Rodríguez-Sánchez et al. PLoS Pathogens
- AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles
- (2019) Truc T. Losier et al. Cell Reports
- Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing
- (2019) Yifan Zhang et al. NATURE IMMUNOLOGY
- Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification
- (2019) Mümine Şentürk et al. NATURE CELL BIOLOGY
- Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
- (2019) Xiang Gui et al. NATURE
- FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates
- (2019) Eleonora Turco et al. MOLECULAR CELL
- Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy
- (2019) Jose Norberto S. Vargas et al. MOLECULAR CELL
- The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria
- (2019) Benjamin J. Ravenhill et al. MOLECULAR CELL
- O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
- (2019) Xinghui Li et al. IMMUNITY
- A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy
- (2019) Yue Xu et al. CELL
- Dendritic cells are what they eat: how their metabolism shapes T helper cell polarization
- (2019) Thiago A Patente et al. CURRENT OPINION IN IMMUNOLOGY
- A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy
- (2019) Qiyao Chai et al. Nature Communications
- SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole
- (2019) Nicole Lau et al. PLoS Pathogens
- Autophagy balances inflammation in innate immunity
- (2018) Vojo Deretic et al. Autophagy
- De novo mutations of the ATP6V1A gene cause developmental encephalopathy with epilepsy
- (2018) Anna Fassio et al. BRAIN
- Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1
- (2018) Ik-Jung Kim et al. Cell Host & Microbe
- Too sweet to resist: Control of immune cell function by O-GlcNAcylation
- (2018) Tristan de Jesus et al. CELLULAR IMMUNOLOGY
- GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion
- (2018) Xiaoyan Zhang et al. DEVELOPMENTAL CELL
- Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1
- (2018) Thaneas Prabakaran et al. EMBO JOURNAL
- The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes
- (2018) Katherine Fletcher et al. EMBO JOURNAL
- FLCN : The causative gene for Birt-Hogg-Dubé syndrome
- (2018) Laura S. Schmidt et al. GENE
- LC3-associated phagocytosis in microbial pathogenesis
- (2018) Stefan Schille et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Galectins at a glance
- (2018) Ludger Johannes et al. JOURNAL OF CELL SCIENCE
- Second-hit mosaic mutation in mTORC1 repressor DEPDC5 causes focal cortical dysplasia–associated epilepsy
- (2018) Théo Ribierre et al. JOURNAL OF CLINICAL INVESTIGATION
- Mechanisms of Gasdermin Family Members in Inflammasome Signaling and Cell Death
- (2018) Shouya Feng et al. JOURNAL OF MOLECULAR BIOLOGY
- Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation
- (2018) Iliana Georgana et al. JOURNAL OF VIROLOGY
- Galectins Control mTOR in Response to Endomembrane Damage
- (2018) Jingyue Jia et al. MOLECULAR CELL
- Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans
- (2018) Thomas Gstrein et al. NATURE NEUROSCIENCE
- Liver X receptors in lipid signalling and membrane homeostasis
- (2018) Bo Wang et al. Nature Reviews Endocrinology
- Autophagy during viral infection — a double-edged sword
- (2018) Younho Choi et al. NATURE REVIEWS MICROBIOLOGY
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells
- (2018) Ricardo J. Antonia et al. Science Signaling
- Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy
- (2018) Wei Liu et al. Cell Death & Disease
- IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells
- (2018) Ricardo J. Antonia et al. Science Signaling
- Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit
- (2018) Nathan Meade et al. CELL
- Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
- (2018) Sung Min Son et al. Cell Metabolism
- The landscape of epilepsy-related GATOR1 variants
- (2018) Sara Baldassari et al. GENETICS IN MEDICINE
- Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation
- (2018) Marianne de la Roche et al. JOURNAL OF CELL BIOLOGY
- BCAP links IL-1R to the PI3K–mTOR pathway and regulates pathogenic Th17 cell differentiation
- (2018) Krystin Deason et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation
- (2018) Mark D. Singh et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Combating herpesvirus encephalitis by potentiating a TLR3–mTORC2 axis
- (2018) Ryota Sato et al. NATURE IMMUNOLOGY
- Activation of RIG-I-Mediated Antiviral Signaling Triggers Autophagy Through the MAVS-TRAF6-Beclin-1 Signaling Axis
- (2018) Na-Rae Lee et al. Frontiers in Immunology
- O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
- (2018) Tianliang Li et al. Cell Host & Microbe
- LAP it up, fuzz ball: a short history of LC3-associated phagocytosis
- (2018) Jennifer Martinez CURRENT OPINION IN IMMUNOLOGY
- Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency
- (2018) Anna S. Lehle et al. GASTROENTEROLOGY
- Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
- (2018) Chuansheng Guo et al. IMMUNITY
- p62/SQSTM1 – steering the cell through health and disease
- (2018) Pablo Sánchez-Martín et al. JOURNAL OF CELL SCIENCE
- mTOR as a central hub of nutrient signalling and cell growth
- (2018) Joungmok Kim et al. NATURE CELL BIOLOGY
- LAMP-2B regulates human cardiomyocyte function by mediating autophagosome–lysosome fusion
- (2018) Congwu Chi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulated proteolysis of p62/SQSTM1 enables differential control of autophagy and nutrient sensing
- (2018) Julia Sanchez-Garrido et al. Science Signaling
- An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread
- (2018) Joel M. J. Tan et al. Nature Microbiology
- Emerging insights into bacterial deubiquitinases
- (2018) Tomoko Kubori et al. CURRENT OPINION IN MICROBIOLOGY
- Clinical Implications for Germline PTEN Spectrum Disorders
- (2017) Joanne Ngeow et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- The mammalian ULK1 complex and autophagy initiation
- (2017) Maria Zachari et al. Essays in Biochemistry
- Host–pathogen interactions and subversion of autophagy
- (2017) David G. McEwan Essays in Biochemistry
- mTORC1 as the main gateway to autophagy
- (2017) Yoana Rabanal-Ruiz et al. Essays in Biochemistry
- TSC1 and TSC2 gene mutations and their implications for treatment in Tuberous Sclerosis Complex: a review
- (2017) Clévia Rosset et al. GENETICS AND MOLECULAR BIOLOGY
- The coccidian parasites Toxoplasma and Neospora dysregulate mammalian lipid droplet biogenesis
- (2017) Xiaoyu Hu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia
- (2017) Marina Minic et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17
- (2017) Xiawei Cheng et al. MOLECULAR CELL
- AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance
- (2017) Daniel Garcia et al. MOLECULAR CELL
- Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence
- (2017) Peng Li et al. NATURE
- Germline hypomorphic CARD11 mutations in severe atopic disease
- (2017) Chi A Ma et al. NATURE GENETICS
- SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology
- (2017) Hitoshi Shimano et al. Nature Reviews Endocrinology
- Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism
- (2017) Maroof Hasan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mycobacterium tuberculosisis protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA
- (2017) Stefan Köster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine
- (2017) Shai Bel et al. SCIENCE
- Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
- (2017) Kohei Arasaki et al. Nature Communications
- Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
- (2017) Hayden Weng Siong Tan et al. Nature Communications
- Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
- (2017) S. Dallari et al. Nature Communications
- TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells
- (2017) Shin-Ichiroh Saitoh et al. Nature Communications
- Positive and Negative Regulation of the Master Metabolic Regulator mTORC1 by Two Families of Legionella pneumophila Effectors
- (2017) Justin A. De Leon et al. Cell Reports
- Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology
- (2017) Patience T. Brace et al. PLoS Pathogens
- Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication
- (2017) Sharon K. Kuss-Duerkop et al. PLoS Pathogens
- Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy
- (2017) Raja Ganesan et al. PLoS Pathogens
- TRIM23 mediates virus-induced autophagy via activation of TBK1
- (2017) Konstantin M. J. Sparrer et al. Nature Microbiology
- Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes
- (2017) Eliana Real et al. Nature Microbiology
- Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
- (2017) Sjoerd J. L. van Wijk et al. Nature Microbiology
- LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB
- (2017) Jessica Noad et al. Nature Microbiology
- Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy
- (2016) Tobias B. Haack et al. AMERICAN JOURNAL OF HUMAN GENETICS
- TRIM-directed selective autophagy regulates immune activation
- (2016) Tomonori Kimura et al. Autophagy
- Metabolism meets immunity: The role of free fatty acid receptors in the immune system
- (2016) Elisa Alvarez-Curto et al. BIOCHEMICAL PHARMACOLOGY
- Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism
- (2016) Andreas Puschmann et al. BRAIN
- TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis
- (2016) Santosh Chauhan et al. DEVELOPMENTAL CELL
- Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy
- (2016) Tomonori Kimura et al. EMBO JOURNAL
- USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin‐1
- (2016) Shouheng Jin et al. EMBO JOURNAL
- Human Monocytes Engage an Alternative Inflammasome Pathway
- (2016) Moritz M. Gaidt et al. IMMUNITY
- Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome
- (2016) Samer Halabi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Physiological Expression ofAMPKγ2RGMutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice
- (2016) Xiaodong Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
- (2016) Thanh Ngoc Nguyen et al. JOURNAL OF CELL BIOLOGY
- Parkin and mitophagy in cancer
- (2016) J P Bernardini et al. ONCOGENE
- Coxiella burnetiieffector CvpB modulates phosphoinositide metabolism for optimal vacuole development
- (2016) Eric Martinez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
- (2016) Kotaro Tsuboyama et al. SCIENCE
- Human TBK1: A Gatekeeper of Neuroinflammation
- (2016) Liyana Ahmad et al. TRENDS IN MOLECULAR MEDICINE
- Bacterial Pathogens versus Autophagy: Implications for Therapeutic Interventions
- (2016) Jacqueline M. Kimmey et al. TRENDS IN MOLECULAR MEDICINE
- MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis
- (2016) Camille F. Abshire et al. PLoS Pathogens
- Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay
- (2016) Myungjin Kim et al. eLife
- A Cap-to-Tail Guide to mRNA Translation Strategies in Virus-Infected Cells
- (2016) Eric Jan et al. Annual Review of Virology
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection
- (2015) David G. McEwan et al. Cell Host & Microbe
- The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
- (2015) Robert O. Watson et al. Cell Host & Microbe
- Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
- (2015) Ruth Wassermann et al. Cell Host & Microbe
- Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis
- (2015) Angela C. Collins et al. Cell Host & Microbe
- PLEKHM2mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction
- (2015) Emad Muhammad et al. HUMAN MOLECULAR GENETICS
- A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity
- (2015) Bao H. Duong et al. IMMUNITY
- Lipopolysaccharides PromoteS-Nitrosylation and Proteasomal Degradation of Liver Kinase B1 (LKB1) in Macrophagesin Vivo
- (2015) Zhaoyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses
- (2015) Barbara Kroczynska et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Exocyst at a Glance
- (2015) B. Wu et al. JOURNAL OF CELL SCIENCE
- Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
- (2015) Philip J. Kranzusch et al. MOLECULAR CELL
- Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection
- (2015) Jacqueline M. Kimmey et al. NATURE
- Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins
- (2015) Jennifer Martinez et al. NATURE CELL BIOLOGY
- Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
- (2015) Xiaodi Su et al. NATURE IMMUNOLOGY
- Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
- (2015) Jae Seok Lim et al. NATURE MEDICINE
- A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis
- (2015) Bappaditya Dey et al. NATURE MEDICINE
- SQSTM1splice site mutation in distal myopathy with rimmed vacuoles
- (2015) Robert C. Bucelli et al. NEUROLOGY
- Differential regulation of mTORC1 by leucine and glutamine
- (2015) J. L. Jewell et al. SCIENCE
- Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation
- (2015) Richard Lu et al. PLoS Pathogens
- Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis
- (2015) Diana Moreira et al. PLoS Pathogens
- Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion
- (2015) Min Zhang et al. eLife
- Clinical delineation and natural history of thePIK3CA-related overgrowth spectrum
- (2014) Kim M. Keppler-Noreuil et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis
- (2014) Bernadette Carroll et al. AMINO ACIDS
- AMP-activated protein kinase activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis
- (2014) Guoqiang Lv et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Metabolic Control of Autophagy
- (2014) Lorenzo Galluzzi et al. CELL
- Phosphoprotein of Human Parainfluenza Virus Type 3 Blocks Autophagosome-Lysosome Fusion to Increase Virus Production
- (2014) Binbin Ding et al. Cell Host & Microbe
- The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense
- (2014) Michiel van der Vaart et al. Cell Host & Microbe
- Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses
- (2014) Qiming Liang et al. Cell Host & Microbe
- TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition
- (2014) Michael A. Mandell et al. DEVELOPMENTAL CELL
- SQSTM1 mutations – Bridging Paget disease of bone and ALS/FTLD
- (2014) Sarah L. Rea et al. EXPERIMENTAL CELL RESEARCH
- Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation
- (2014) Mako Nakaya et al. IMMUNITY
- Liver Kinase B1 Suppresses Lipopolysaccharide-induced Nuclear Factor κB (NF-κB) Activation in Macrophages
- (2014) Zhaoyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis
- (2014) Sayaka Inokuchi-Shimizu et al. JOURNAL OF CLINICAL INVESTIGATION
- A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3
- (2014) Aditya Murthy et al. NATURE
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T Cell Receptor-Dependent Activation of mTOR Signaling in T Cells Is Mediated by Carma1 and MALT1, But Not Bcl10
- (2014) K. S. Hamilton et al. Science Signaling
- Activation of Focal Adhesion Kinase by Salmonella Suppresses Autophagy via an Akt/mTOR Signaling Pathway and Promotes Bacterial Survival in Macrophages
- (2014) Katherine A. Owen et al. PLoS Pathogens
- A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis
- (2014) Hayley J. Newton et al. PLoS Pathogens
- TBK1Gene Duplication and Normal-Tension Glaucoma
- (2014) Robert Ritch et al. JAMA Ophthalmology
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
- (2013) Hiroyasu Konno et al. CELL
- Arp2/3-Mediated Actin-Based Motility: A Tail of Pathogen Abuse
- (2013) Matthew D. Welch et al. Cell Host & Microbe
- AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
- (2013) Graeme J. Gowans et al. Cell Metabolism
- Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies
- (2013) David Ellinghaus et al. GASTROENTEROLOGY
- Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation
- (2013) Yiqing Yan et al. IMMUNITY
- AKT1 Gene Mutation Levels Are Correlated with the Type of Dermatologic Lesions in Patients with Proteus Syndrome
- (2013) Marjorie J. Lindhurst et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells
- (2013) Juan F. Linares et al. MOLECULAR CELL
- The ubiquitin ligase parkin mediates resistance to intracellular pathogens
- (2013) Paolo S. Manzanillo et al. NATURE
- The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response
- (2013) Michal Simicek et al. NATURE CELL BIOLOGY
- Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR
- (2013) Stanimir S Ivanov et al. NATURE IMMUNOLOGY
- Germline PIK3CA and AKT1 Mutations in Cowden and Cowden-like Syndromes
- (2012) Mohammed S. Orloff et al. AMERICAN JOURNAL OF HUMAN GENETICS
- IFN-Inducible GTPases in Host Cell Defense
- (2012) Bae-Hoon Kim et al. Cell Host & Microbe
- The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium
- (2012) Alan Huett et al. Cell Host & Microbe
- Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program
- (2012) Ivan Tattoli et al. Cell Host & Microbe
- Vacuolating Cytotoxin and Variants in Atg16L1 That Disrupt Autophagy Promote Helicobacter pylori Infection in Humans
- (2012) Deepa Raju et al. GASTROENTEROLOGY
- Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes
- (2012) Jill Henault et al. IMMUNITY
- IFN- Elicits Macrophage Autophagy via the p38 MAPK Signaling Pathway
- (2012) T. Matsuzawa et al. JOURNAL OF IMMUNOLOGY
- Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
- (2012) Teresa L. M. Thurston et al. NATURE
- De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes
- (2012) Jean-Baptiste Rivière et al. NATURE GENETICS
- De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly
- (2012) Jeong Ho Lee et al. NATURE GENETICS
- Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
- (2012) Maroof Hasan et al. NATURE IMMUNOLOGY
- Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses
- (2012) S. Kaur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation
- (2012) A. Choy et al. SCIENCE
- PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
- (2011) Tamas Varga et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly
- (2011) Brian O. Bodemann et al. CELL
- Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection
- (2011) Maritza Jaramillo et al. Cell Host & Microbe
- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
- (2011) Nicolas Dupont et al. EMBO JOURNAL
- Autophagy in immunity and cell-autonomous defense against intracellular microbes
- (2011) Vojo Deretic IMMUNOLOGICAL REVIEWS
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor
- (2011) Miguel A Mata et al. Nature Chemical Biology
- Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers
- (2011) Daiki Miki et al. NATURE GENETICS
- Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt
- (2011) T. D. Troutman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
- (2010) Sven Geisler et al. Autophagy
- AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts
- (2010) Young-Sun Lee et al. BONE
- Peutz-Jeghers syndrome: a systematic review and recommendations for management
- (2010) A. D. Beggs et al. GUT
- Pro-autophagic signal induction by bacterial pore-forming toxins
- (2010) Nicole Kloft et al. MEDICAL MICROBIOLOGY AND IMMUNOLOGY
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy
- (2010) C. S. Shi et al. Science Signaling
- Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes
- (2009) Monique Gannagé et al. Cell Host & Microbe
- TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells
- (2009) Griselda Herrero-Martín et al. EMBO JOURNAL
- The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
- (2009) Teresa L M Thurston et al. NATURE IMMUNOLOGY
- CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior
- (2009) R. L. Silverstein et al. Science Signaling
- Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells
- (2008) Frank Schmitz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
- (2008) Weiping Cao et al. NATURE IMMUNOLOGY
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